CA2317010A1 - Topical ophthalmic preparations containing immunosuppressive agents - Google Patents
Topical ophthalmic preparations containing immunosuppressive agents Download PDFInfo
- Publication number
- CA2317010A1 CA2317010A1 CA002317010A CA2317010A CA2317010A1 CA 2317010 A1 CA2317010 A1 CA 2317010A1 CA 002317010 A CA002317010 A CA 002317010A CA 2317010 A CA2317010 A CA 2317010A CA 2317010 A1 CA2317010 A1 CA 2317010A1
- Authority
- CA
- Canada
- Prior art keywords
- weight
- preparations
- immunosuppressive agents
- ciclosporin
- cornea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000011492 sheep wool Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000003637 steroidlike Effects 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ19974237A CZ287497B6 (cs) | 1997-12-30 | 1997-12-30 | Topické oční přípravky s imunosupresivními látkami |
| CZPV4237-97 | 1997-12-30 | ||
| PCT/CZ1998/000054 WO1999034830A1 (en) | 1997-12-30 | 1998-12-17 | Topical ophthalmic preparations containing immunosuppressive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2317010A1 true CA2317010A1 (en) | 1999-07-15 |
Family
ID=5467853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002317010A Abandoned CA2317010A1 (en) | 1997-12-30 | 1998-12-17 | Topical ophthalmic preparations containing immunosuppressive agents |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1058560A1 (cs) |
| JP (1) | JP2002500200A (cs) |
| AU (1) | AU1481399A (cs) |
| BG (1) | BG104558A (cs) |
| CA (1) | CA2317010A1 (cs) |
| CZ (1) | CZ287497B6 (cs) |
| HR (1) | HRP20000258A2 (cs) |
| HU (1) | HUP0004173A2 (cs) |
| NO (1) | NO20003344D0 (cs) |
| PL (1) | PL341604A1 (cs) |
| SK (1) | SK284246B6 (cs) |
| WO (1) | WO1999034830A1 (cs) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10172789B2 (en) | 2013-01-24 | 2019-01-08 | Palvella Therapeutics Llc | Compositions for transdermal delivery of mTOR inhibitors |
| US10722499B2 (en) | 2017-01-06 | 2020-07-28 | Palvella Therapeutics, Inc. | Anyhydrous compositions of mTOR inhibitors and methods of use |
| US11000513B2 (en) | 2018-07-02 | 2021-05-11 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6864232B1 (en) | 1998-12-24 | 2005-03-08 | Sucampo Ag | Agent for treating visual cell function disorder |
| CA2356382A1 (en) * | 1998-12-24 | 2000-07-06 | R-Tech Ueno, Ltd. | Agent for treating visual cell function disorder |
| TWI324925B (en) * | 2001-08-23 | 2010-05-21 | Novartis Ag | Ophthalmic composition |
| AU2003272471B2 (en) | 2002-09-18 | 2010-10-07 | Trustees Of The University Of Pennsylvania | Method of inhibiting choroidal neovascularization |
| US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| US7083802B2 (en) * | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| AU2004274026A1 (en) | 2003-09-18 | 2005-03-31 | Macusight, Inc. | Transscleral delivery |
| US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| US7083803B2 (en) | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
| WO2006086744A1 (en) | 2005-02-09 | 2006-08-17 | Macusight, Inc. | Formulations for ocular treatment |
| AU2006270041B2 (en) | 2005-07-18 | 2011-08-18 | Minu, Llc | Enhanced ocular neuroprotection/neurostimulation |
| CN101605529B (zh) | 2006-02-09 | 2013-03-13 | 参天制药株式会社 | 稳定制剂及它们的制备和使用方法 |
| CN103127100A (zh) | 2006-03-23 | 2013-06-05 | 参天制药株式会社 | 用于与血管通透性有关的疾病或病症的制剂和方法 |
| AU2013384818A1 (en) * | 2013-03-27 | 2015-11-12 | Comprehensive Drug Enterprises, Ltd. | Ophthalmic composition, method for preparing the same, and use of the same |
| JP6960937B2 (ja) | 2016-03-08 | 2021-11-05 | リビング プルーフ インコーポレイテッド | 長期持続性化粧品組成物 |
| JP7244495B2 (ja) | 2017-09-13 | 2023-03-22 | リビング プルーフ インコーポレイテッド | 長期持続性の化粧品組成物 |
| WO2019055445A2 (en) | 2017-09-13 | 2019-03-21 | Living Proof, Inc. | COLOR PROTECTION COMPOSITIONS |
| WO2019099966A1 (en) | 2017-11-20 | 2019-05-23 | Living Proof, Inc. | Properties for achieving long-lasting cosmetic performance |
| EP3784711A1 (en) | 2018-04-27 | 2021-03-03 | Living Proof, Inc. | Long lasting cosmetic compositions |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5051260A (en) * | 1987-07-16 | 1991-09-24 | The Regents Of The University Of California | Method and composition for enhancing the cutaneous penetration of pharmacologically active agents |
| US4971800A (en) * | 1988-07-08 | 1990-11-20 | The Regents Of The University Of California | Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents |
| US5045317A (en) * | 1987-07-16 | 1991-09-03 | The Regents Of The University Of California | Enhancing the cutaneous penetration of pharmacologically active agents |
-
1997
- 1997-12-30 CZ CZ19974237A patent/CZ287497B6/cs not_active IP Right Cessation
-
1998
- 1998-12-14 SK SK1717-98A patent/SK284246B6/sk not_active IP Right Cessation
- 1998-12-17 CA CA002317010A patent/CA2317010A1/en not_active Abandoned
- 1998-12-17 WO PCT/CZ1998/000054 patent/WO1999034830A1/en not_active Application Discontinuation
- 1998-12-17 AU AU14813/99A patent/AU1481399A/en not_active Abandoned
- 1998-12-17 EP EP98958793A patent/EP1058560A1/en not_active Withdrawn
- 1998-12-17 JP JP2000527277A patent/JP2002500200A/ja not_active Withdrawn
- 1998-12-17 HR HR20000258A patent/HRP20000258A2/hr not_active Application Discontinuation
- 1998-12-17 HU HU0004173A patent/HUP0004173A2/hu unknown
- 1998-12-17 PL PL98341604A patent/PL341604A1/xx unknown
-
2000
- 2000-06-27 NO NO20003344A patent/NO20003344D0/no not_active Application Discontinuation
- 2000-06-27 BG BG104558A patent/BG104558A/xx unknown
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10172789B2 (en) | 2013-01-24 | 2019-01-08 | Palvella Therapeutics Llc | Compositions for transdermal delivery of mTOR inhibitors |
| US10722499B2 (en) | 2017-01-06 | 2020-07-28 | Palvella Therapeutics, Inc. | Anyhydrous compositions of mTOR inhibitors and methods of use |
| US11135204B2 (en) | 2017-01-06 | 2021-10-05 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| US12268673B2 (en) | 2017-01-06 | 2025-04-08 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| US11000513B2 (en) | 2018-07-02 | 2021-05-11 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| US11679101B2 (en) | 2018-07-02 | 2023-06-20 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| US12329748B2 (en) | 2018-07-02 | 2025-06-17 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
Also Published As
| Publication number | Publication date |
|---|---|
| PL341604A1 (en) | 2001-04-23 |
| HRP20000258A2 (en) | 2001-04-30 |
| WO1999034830A1 (en) | 1999-07-15 |
| CZ287497B6 (cs) | 2000-12-13 |
| SK284246B6 (sk) | 2004-12-01 |
| EP1058560A1 (en) | 2000-12-13 |
| AU1481399A (en) | 1999-07-26 |
| JP2002500200A (ja) | 2002-01-08 |
| BG104558A (en) | 2001-02-28 |
| HUP0004173A2 (hu) | 2001-08-28 |
| NO20003344L (no) | 2000-06-27 |
| NO20003344D0 (no) | 2000-06-27 |
| SK171798A3 (en) | 1999-10-08 |
| CZ423797A3 (cs) | 1999-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |