CA2315746A1 - Vaccin a base de lipooligosaccharide destine a la prevention d'infections dues a moraxella (branhamella) catarrhalis chez les mammaliens - Google Patents
Vaccin a base de lipooligosaccharide destine a la prevention d'infections dues a moraxella (branhamella) catarrhalis chez les mammaliens Download PDFInfo
- Publication number
- CA2315746A1 CA2315746A1 CA002315746A CA2315746A CA2315746A1 CA 2315746 A1 CA2315746 A1 CA 2315746A1 CA 002315746 A CA002315746 A CA 002315746A CA 2315746 A CA2315746 A CA 2315746A CA 2315746 A1 CA2315746 A1 CA 2315746A1
- Authority
- CA
- Canada
- Prior art keywords
- dlos
- los
- catarrhalis
- isolated
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
- A61K39/1045—Moraxella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
L'invention concerne un vaccin conjugué contre Moraxella (Branhamella) catarrhalis comprenant un lipooligosaccharide isolé dont on retiré des acides gras estérifiés pour produire un lipooligosaccharide détoxiqué (dLOS), ou dont on a retiré un lipide A pour produire un oligosaccharide détoxiqué (OS), qui est lié à un excipient immunogène. Le vaccin s'utilise pour la prévention de l'otite moyenne et des infections respiratoires provoquées par M. catarrhalis chez des mammaliens, y compris des humains.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7148398P | 1998-01-13 | 1998-01-13 | |
US60/071,483 | 1998-01-13 | ||
PCT/US1999/000590 WO1999036086A1 (fr) | 1998-01-13 | 1999-01-12 | Vaccin a base de lipooligosaccharide destine a la prevention d'infections dues a moraxella (branhamella) catarrhalis chez les mammaliens |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2315746A1 true CA2315746A1 (fr) | 1999-07-22 |
Family
ID=22101617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002315746A Abandoned CA2315746A1 (fr) | 1998-01-13 | 1999-01-12 | Vaccin a base de lipooligosaccharide destine a la prevention d'infections dues a moraxella (branhamella) catarrhalis chez les mammaliens |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1047447A1 (fr) |
JP (1) | JP2002509115A (fr) |
KR (1) | KR20010034124A (fr) |
CN (1) | CN1288384A (fr) |
AU (2) | AU2221299A (fr) |
BR (1) | BR9906902A (fr) |
CA (1) | CA2315746A1 (fr) |
IL (1) | IL136903A0 (fr) |
WO (1) | WO1999036086A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040126381A1 (en) | 1996-04-23 | 2004-07-01 | Xin-Xing Gu | Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella |
WO2002089839A1 (fr) * | 2001-05-03 | 2002-11-14 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunisation intranasale par un lipooligosaccharide detoxifie provenant d'un haemophilus influenzae ou d'un moraxella catarrhalis non typable |
US6391313B1 (en) * | 1999-07-15 | 2002-05-21 | Aventis Pasteur Limited | Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis |
WO2006085910A2 (fr) * | 2004-06-04 | 2006-08-17 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Moraxella catarrhalis exempte d'endotoxine |
CN104592365B (zh) * | 2013-11-01 | 2019-06-14 | 中国人民解放军军事医学科学院毒物药物研究所 | 梭曼抗原、梭曼疫苗及其用途 |
EP3706787A4 (fr) * | 2017-11-06 | 2021-10-20 | OZQ Pty Ltd | Vaccin |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998053851A1 (fr) * | 1997-05-28 | 1998-12-03 | University Of Iowa Research Foundation | Mutants laft de bacteries pathogenes gram negatif |
-
1999
- 1999-01-12 CA CA002315746A patent/CA2315746A1/fr not_active Abandoned
- 1999-01-12 EP EP99902170A patent/EP1047447A1/fr not_active Withdrawn
- 1999-01-12 WO PCT/US1999/000590 patent/WO1999036086A1/fr not_active Application Discontinuation
- 1999-01-12 JP JP2000539859A patent/JP2002509115A/ja active Pending
- 1999-01-12 KR KR1020007007737A patent/KR20010034124A/ko not_active Application Discontinuation
- 1999-01-12 AU AU22212/99A patent/AU2221299A/en not_active Abandoned
- 1999-01-12 CN CN99802142A patent/CN1288384A/zh active Pending
- 1999-01-12 IL IL13690399A patent/IL136903A0/xx unknown
- 1999-01-12 BR BR9906902-4A patent/BR9906902A/pt not_active Application Discontinuation
-
2003
- 2003-02-21 AU AU2003200964A patent/AU2003200964B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CN1288384A (zh) | 2001-03-21 |
AU2003200964A8 (en) | 2003-06-12 |
AU2221299A (en) | 1999-08-02 |
KR20010034124A (ko) | 2001-04-25 |
WO1999036086A1 (fr) | 1999-07-22 |
JP2002509115A (ja) | 2002-03-26 |
BR9906902A (pt) | 2000-10-17 |
EP1047447A1 (fr) | 2000-11-02 |
AU2003200964B2 (en) | 2004-11-11 |
AU2003200964A1 (en) | 2003-06-12 |
IL136903A0 (en) | 2001-06-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |