BR9906902A - "vacina de conjugado para moraxella catarrhalis, composição farmacêutica, lipooligossacarìdeo, e, processos de prevenção de otite média causada pela infecção com moraxella catarrhalis em um mamìfero, de desintoxicação de lipooligossacarìdeo (los) isolado de moraxella catarrhalis, e de preparação de uma vacina de conjugado contra moraxella catarrhalis" - Google Patents

"vacina de conjugado para moraxella catarrhalis, composição farmacêutica, lipooligossacarìdeo, e, processos de prevenção de otite média causada pela infecção com moraxella catarrhalis em um mamìfero, de desintoxicação de lipooligossacarìdeo (los) isolado de moraxella catarrhalis, e de preparação de uma vacina de conjugado contra moraxella catarrhalis"

Info

Publication number
BR9906902A
BR9906902A BR9906902-4A BR9906902A BR9906902A BR 9906902 A BR9906902 A BR 9906902A BR 9906902 A BR9906902 A BR 9906902A BR 9906902 A BR9906902 A BR 9906902A
Authority
BR
Brazil
Prior art keywords
moraxella catarrhalis
lipooligosaccharide
vaccine
catarrhalis
moraxella
Prior art date
Application number
BR9906902-4A
Other languages
English (en)
Inventor
Xin-Xing Gu
John B Robbins
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of BR9906902A publication Critical patent/BR9906902A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A61K39/1045—Moraxella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

''VACINA DE CONJUGADO PARA MORAXELLA CATARRHALIS, COMPOSIçãO FARMACêUTICA, LIPOOLIGOSSACARìDEO, E, PROCESSOS DE PREVENçãO DE OTITE MéDIA CAUSADA PELA INFECçãO COM MORAXELLA CATARRHALIS EM UM MAMìFERO, DE DESINTOXICAçãO DE LIPOOLIGOSSACARìDEO (LOS) ISOLADO DE MORAXELLA CATARRHALIS, E DE PREPARAçãO DE UMA VACINA DE CONJUGADO CONTRA MORAXELLA CATARRHALIS'' Uma vacina de conjugado para Moraxella (Branhamella) catarrhalis compreendendo lipooligossacarídeo isolado do qual ácidos graxos esterificados foram removidos, para produzir um lipooligossacarídeo desintoxicado (dLOS), ou do qual lipídeo A foi removido, para produzir um oligossacarídeo (OS) desintoxicado, que é ligado em um veículo imunogênico. A vacina é útil para prevenção de otite média e de infecções respiratórias causadas por M. catarrhalis em mamíferos, incluindo humanos.
BR9906902-4A 1998-01-13 1999-01-12 "vacina de conjugado para moraxella catarrhalis, composição farmacêutica, lipooligossacarìdeo, e, processos de prevenção de otite média causada pela infecção com moraxella catarrhalis em um mamìfero, de desintoxicação de lipooligossacarìdeo (los) isolado de moraxella catarrhalis, e de preparação de uma vacina de conjugado contra moraxella catarrhalis" BR9906902A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7148398P 1998-01-13 1998-01-13
PCT/US1999/000590 WO1999036086A1 (en) 1998-01-13 1999-01-12 Lipooligosaccharide-based vaccine for prevention of moraxella (branhamella) catarrhalis infections in mammals

Publications (1)

Publication Number Publication Date
BR9906902A true BR9906902A (pt) 2000-10-17

Family

ID=22101617

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9906902-4A BR9906902A (pt) 1998-01-13 1999-01-12 "vacina de conjugado para moraxella catarrhalis, composição farmacêutica, lipooligossacarìdeo, e, processos de prevenção de otite média causada pela infecção com moraxella catarrhalis em um mamìfero, de desintoxicação de lipooligossacarìdeo (los) isolado de moraxella catarrhalis, e de preparação de uma vacina de conjugado contra moraxella catarrhalis"

Country Status (9)

Country Link
EP (1) EP1047447A1 (pt)
JP (1) JP2002509115A (pt)
KR (1) KR20010034124A (pt)
CN (1) CN1288384A (pt)
AU (2) AU2221299A (pt)
BR (1) BR9906902A (pt)
CA (1) CA2315746A1 (pt)
IL (1) IL136903A0 (pt)
WO (1) WO1999036086A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002089839A1 (en) * 2001-05-03 2002-11-14 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella catarrhalis
US20040126381A1 (en) 1996-04-23 2004-07-01 Xin-Xing Gu Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella
US6391313B1 (en) * 1999-07-15 2002-05-21 Aventis Pasteur Limited Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis
WO2006085910A2 (en) * 2004-06-04 2006-08-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Endotoxin-free moraxella catarrhalis
CN104592365B (zh) * 2013-11-01 2019-06-14 中国人民解放军军事医学科学院毒物药物研究所 梭曼抗原、梭曼疫苗及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7701098A (en) * 1997-05-28 1998-12-30 Michael A. Apicella Laft mutants of pathogenic gram-negative bacteria

Also Published As

Publication number Publication date
CA2315746A1 (en) 1999-07-22
KR20010034124A (ko) 2001-04-25
AU2003200964A1 (en) 2003-06-12
CN1288384A (zh) 2001-03-21
EP1047447A1 (en) 2000-11-02
JP2002509115A (ja) 2002-03-26
AU2003200964B2 (en) 2004-11-11
WO1999036086A1 (en) 1999-07-22
AU2221299A (en) 1999-08-02
AU2003200964A8 (en) 2003-06-12
IL136903A0 (en) 2001-06-14

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO DE ACORDO COM OS ARTS. 10 (VIII), 24E 32 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.