CA2305394C - Apport local d'inhibiteurs de phosphodiesterases, dans le traitement du dysfonctionnement erectile - Google Patents
Apport local d'inhibiteurs de phosphodiesterases, dans le traitement du dysfonctionnement erectile Download PDFInfo
- Publication number
- CA2305394C CA2305394C CA002305394A CA2305394A CA2305394C CA 2305394 C CA2305394 C CA 2305394C CA 002305394 A CA002305394 A CA 002305394A CA 2305394 A CA2305394 A CA 2305394A CA 2305394 C CA2305394 C CA 2305394C
- Authority
- CA
- Canada
- Prior art keywords
- phosphodiesterase inhibitor
- phosphodiesterase
- type
- use according
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Abstract
L'invention concerne un procédé de traitement du dysfonctionnement érectile chez un individu mâle mammifère. Ce procédé consiste à apporter localement un inhibiteur des phosphodiestérases, ou un sel, ester, amide ou dérivé de celui-ci, acceptable sur le plan pharmacologique, dans le cadre d'un schéma posologique efficace. Un mode préféré d'administration est un mode transurétral. L'invention concerne également des formulations et des coffrets pharmaceutiques.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95881697A | 1997-10-28 | 1997-10-28 | |
US08/958,816 | 1997-10-28 | ||
US09/181,070 | 1998-10-27 | ||
US09/181,070 US6037346A (en) | 1997-10-28 | 1998-10-27 | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
PCT/US1998/022928 WO1999021558A2 (fr) | 1997-10-28 | 1998-10-28 | Apport local d'inhibiteurs de phosphodiesterases, dans le traitement du dysfonctionnement erectile |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2305394A1 CA2305394A1 (fr) | 1999-05-06 |
CA2305394C true CA2305394C (fr) | 2006-12-12 |
Family
ID=25501340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002305394A Expired - Lifetime CA2305394C (fr) | 1997-10-28 | 1998-10-28 | Apport local d'inhibiteurs de phosphodiesterases, dans le traitement du dysfonctionnement erectile |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1027054A4 (fr) |
JP (1) | JP2003525845A (fr) |
AU (1) | AU734734B2 (fr) |
CA (1) | CA2305394C (fr) |
WO (1) | WO1999021558A2 (fr) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6331543B1 (en) | 1996-11-01 | 2001-12-18 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use |
CA2295595A1 (fr) | 1997-07-09 | 1999-01-21 | Androsolutions, Inc. | Compositions et procedes perfectionnes de traitement des troubles de l'erection chez l'homme |
US6103765A (en) | 1997-07-09 | 2000-08-15 | Androsolutions, Inc. | Methods for treating male erectile dysfunction |
US6548490B1 (en) * | 1997-10-28 | 2003-04-15 | Vivus, Inc. | Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
US6403597B1 (en) | 1997-10-28 | 2002-06-11 | Vivus, Inc. | Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation |
US6472425B1 (en) | 1997-10-31 | 2002-10-29 | Nitromed, Inc. | Methods for treating female sexual dysfunctions |
US6541487B1 (en) * | 1998-05-01 | 2003-04-01 | R.T. Alamo Ventures I, Llc | PDE III inhibitors for treating sexual dysfunction |
DE19834506A1 (de) * | 1998-07-31 | 2000-02-03 | Hexal Ag | Transmucosales therapeutisches System zur Anwendung von Sildenafil |
EP1157694A4 (fr) * | 1998-12-07 | 2002-08-28 | Nissan Chemical Ind Ltd | Agent therapeutique pour le traitement de la dyserection |
IT1312310B1 (it) * | 1999-05-07 | 2002-04-15 | Recordati Ind Chimica E Farma | Uso di antagonisti selettivi del recettore adrenergico a 1b per ilmiglioramento della disfunzione sessuale |
IL130968A (en) * | 1999-07-15 | 2002-12-01 | Shmuel Simon | Pharmaceutical composition comprising sildenafil or its analogs, useful for the treatment of tinnitus and hearing loss |
US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
AU2001273636A1 (en) | 2000-06-27 | 2002-01-08 | Qualilife Pharmaceuticals Inc. | Compositions and methods for treating females sexual response |
US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
US6821978B2 (en) | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
FI20002755A0 (fi) * | 2000-12-15 | 2000-12-15 | Orion Yhtymae Oyj | Menetelmä erektiilin dysfunktion hoitamiseen |
CA2431077A1 (fr) * | 2000-12-19 | 2002-06-27 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Formulation pharmaceutique contenant des pyrazolo[4,3-d]pyrimidines et des antithrombotiques, des antagonistes de calcium, des prostaglandines ou des derives de prostaglandine |
US20040058940A1 (en) * | 2000-12-19 | 2004-03-25 | Hans-Michael Eggenweiler | Pharmaceutical formulation comprising thienopyrimidines and antithrombotics, calcium antagonists, prostaglandins or prostaglandin derivatives (2) |
HUP0303289A2 (hu) * | 2000-12-19 | 2004-01-28 | Merck Patent Gmbh. | Tienopirimidineket és trombózisellenes szereket, kalcium antagonistákat, prosztaglandinokat vagy prosztaglandinszármazékokat tartalmazó gyógyszerkészítmények |
EP1224933A1 (fr) * | 2001-01-19 | 2002-07-24 | Sanofi-Synthelabo | Nouvelle combinaison d'actifs avec alfuzosine et apomorphine |
US6943171B2 (en) | 2001-11-09 | 2005-09-13 | Schering Corporation | Polycyclic guanine derivative phosphodiesterase V inhibitors |
PT2311432E (pt) | 2002-06-07 | 2015-02-09 | Dyax Corp | Polipeptídeos de domínio kunitz modificado e sua utilização para a redução de isquemia ou aparecimento de uma resposta inflamatória sistémica associada a um procedimento cirúrgico |
WO2004071533A1 (fr) * | 2003-02-14 | 2004-08-26 | Takeda Pharmaceutical Company Limited | Preparation pour administration topique |
WO2005021557A2 (fr) * | 2003-08-29 | 2005-03-10 | Dyax Corp. | Inhibiteurs de protease poly-pegylee |
US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
DK1802277T3 (da) * | 2004-10-18 | 2010-05-17 | Polymun Scient Immunbio Forsch | Liposomal sammensætning indeholdende en aktiv bestanddel til relaksation af glat muskulatur og terapeutisk anvendelse af sammensætningen |
KR20140054312A (ko) * | 2007-02-12 | 2014-05-08 | 디엠아이 바이오사이언시스 인코포레이티드 | 조루 및 발기부전을 동시에 치료하는 방법 |
KR20100050488A (ko) * | 2007-06-26 | 2010-05-13 | 솔베이 파마슈티칼스 비. 브이 | 전구약물로서 실데나필 n-옥사이드 |
KR102555955B1 (ko) | 2014-03-27 | 2023-07-18 | 다케다 파머수티컬 컴패니 리미티드 | 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법 |
WO2021027943A1 (fr) * | 2019-08-14 | 2021-02-18 | 正大天晴药业集团南京顺欣制药有限公司 | Dérivé de pyrimidinopyridazinone et son utilisation médicale |
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US4801587A (en) * | 1987-03-02 | 1989-01-31 | Gene Voss | Impotence ointment |
FR2649613B1 (fr) * | 1989-07-11 | 1991-09-27 | Virag Ronald | Medicament vaso-actif |
US5242391A (en) * | 1990-04-25 | 1993-09-07 | Alza Corporation | Urethral insert for treatment of erectile dysfunction |
US5250534A (en) * | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
GB9114760D0 (en) * | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
GB9301192D0 (en) * | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
GB9423910D0 (en) * | 1994-11-26 | 1995-01-11 | Pfizer Ltd | Therapeutic agents |
WO1998019672A1 (fr) * | 1996-11-01 | 1998-05-14 | Nitromed Inc. | Composes nitroses et nitrosyles inhibiteurs de la phosphodiesterase, compositions comprenant ces composes et utilisations correspondantes |
JP2001505198A (ja) * | 1996-11-20 | 2001-04-17 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | Pde阻害剤としての置換ジヒドロベンゾフラン |
JP2001520999A (ja) * | 1997-10-28 | 2001-11-06 | アシビ, エルエルシー | 女性の性的機能不全の処置 |
-
1998
- 1998-10-28 JP JP2000517716A patent/JP2003525845A/ja active Pending
- 1998-10-28 EP EP19980954032 patent/EP1027054A4/fr not_active Ceased
- 1998-10-28 AU AU11254/99A patent/AU734734B2/en not_active Ceased
- 1998-10-28 WO PCT/US1998/022928 patent/WO1999021558A2/fr not_active Application Discontinuation
- 1998-10-28 CA CA002305394A patent/CA2305394C/fr not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU734734B2 (en) | 2001-06-21 |
WO1999021558A2 (fr) | 1999-05-06 |
WO1999021558A3 (fr) | 2000-10-26 |
EP1027054A4 (fr) | 2002-11-04 |
EP1027054A1 (fr) | 2000-08-16 |
JP2003525845A (ja) | 2003-09-02 |
AU1125499A (en) | 1999-05-17 |
CA2305394A1 (fr) | 1999-05-06 |
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