CA2304949A1 - Diagnostic test for alzheimer's disease - Google Patents

Diagnostic test for alzheimer's disease Download PDF

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Publication number
CA2304949A1
CA2304949A1 CA002304949A CA2304949A CA2304949A1 CA 2304949 A1 CA2304949 A1 CA 2304949A1 CA 002304949 A CA002304949 A CA 002304949A CA 2304949 A CA2304949 A CA 2304949A CA 2304949 A1 CA2304949 A1 CA 2304949A1
Authority
CA
Canada
Prior art keywords
ache
glycosylation pattern
csf
isoform
alzheimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002304949A
Other languages
English (en)
French (fr)
Inventor
David Henry Small
Javier Saez-Valero
Gian Sberna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monash University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2304949A1 publication Critical patent/CA2304949A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/916Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/827Actinoplanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA002304949A 1997-09-24 1998-09-24 Diagnostic test for alzheimer's disease Abandoned CA2304949A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO9432A AUPO943297A0 (en) 1997-09-24 1997-09-24 Diagnostic test for alzheimer's disease
AUPO9432 1997-09-24
PCT/AU1998/000809 WO1999015695A1 (en) 1997-09-24 1998-09-24 Diagnostic test for alzheimer's disease

Publications (1)

Publication Number Publication Date
CA2304949A1 true CA2304949A1 (en) 1999-04-01

Family

ID=3803714

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002304949A Abandoned CA2304949A1 (en) 1997-09-24 1998-09-24 Diagnostic test for alzheimer's disease

Country Status (11)

Country Link
US (1) US6461831B1 (https=)
EP (1) EP1017845B1 (https=)
JP (1) JP2001517456A (https=)
AT (1) ATE323781T1 (https=)
AU (1) AUPO943297A0 (https=)
BR (1) BR9813015A (https=)
CA (1) CA2304949A1 (https=)
DE (1) DE69834263D1 (https=)
HU (1) HUP0003684A3 (https=)
IL (1) IL135211A0 (https=)
WO (1) WO1999015695A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL130225A0 (en) 1999-05-31 2000-06-01 Yissum Res Dev Co Novel uses of antibodies against ache and peptides thereof
US20020150878A1 (en) * 2001-01-23 2002-10-17 Small David Henry Method for the diagnosis of Alzheimer's Disease and other prion related disorders
JP2006515927A (ja) * 2002-12-20 2006-06-08 モメンタ ファーマシューティカルズ インコーポレイテッド 疾患を診断および監視するためのグリカンマーカー
GB2404734A (en) * 2003-08-05 2005-02-09 Secr Defence A method of screening a sample for abnormally glycosylated and/or expressed proteins
US20060094064A1 (en) * 2003-11-19 2006-05-04 Sandip Ray Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids
JP2007513337A (ja) * 2003-11-19 2007-05-24 サトリス, インコーポレイテッド アルツハイマー病の診断方法、層化方法およびモニタリング方法
US20050272643A1 (en) * 2004-06-08 2005-12-08 Windber Research Institute Removal of serum albumin from human serum or plasma
US7851172B2 (en) 2006-07-25 2010-12-14 University Of Kentucky Research Foundation Biomarkers of mild cognitive impairment and alzheimer's disease
US20100124756A1 (en) * 2008-10-10 2010-05-20 Sandip Ray Collection of biomarkers for diagnosis and monitoring of alzheimer's disease in body fluids
US20110237537A1 (en) * 2009-05-29 2011-09-29 Lombard Jay L Methods for assessment and treatment of mood disorders via single nucleotide polymorphisms analysis
US8355927B2 (en) 2010-11-05 2013-01-15 Genomind, Llc Neuropsychiatric test reports
US9493834B2 (en) 2009-07-29 2016-11-15 Pharnext Method for detecting a panel of biomarkers
US20110202284A1 (en) * 2010-02-10 2011-08-18 Mcreynolds Cristopher Novel groups of biomarkers for diagnosing alzheimer's disease
ES2395063B1 (es) * 2011-03-04 2014-02-07 Universidad Miguel Hernández De Elche Método para determinar la enfermedad de Alzheimer mediante la detección de glicoproteínas portadoras del glicoepítopo HNK-1
CA2877975C (en) 2012-04-13 2021-09-21 Oasis Diagnostics Corporation Specific salivary biomarkers for risk detection, early diagnosis, prognosis and monitoring of alzheimer's and parkinson's diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595883A (en) * 1990-06-01 1997-01-21 E. R. Squibb & Sons, Inc. Method of diagnosing alzheimer's disease by measuring acetylcholinesterase activity in ocular fluid
CA2048700A1 (en) 1990-09-04 1992-03-05 Dasakumar S. Navaratnam Method for diagnosing senile dementia of the alzheimer type
US5200324A (en) * 1990-09-04 1993-04-06 E. R. Squibb & Sons, Inc. Method of diagnosing senile dementia of the Alzheimer type

Also Published As

Publication number Publication date
WO1999015695A1 (en) 1999-04-01
ATE323781T1 (de) 2006-05-15
EP1017845B1 (en) 2006-04-19
EP1017845A1 (en) 2000-07-12
JP2001517456A (ja) 2001-10-09
HUP0003684A2 (hu) 2001-02-28
US6461831B1 (en) 2002-10-08
EP1017845A4 (en) 2003-07-02
DE69834263D1 (de) 2006-05-24
IL135211A0 (en) 2001-05-20
AUPO943297A0 (en) 1997-10-16
BR9813015A (pt) 2000-08-15
HUP0003684A3 (en) 2003-04-28

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued