ATE323781T1 - Diagnostischer test für die alzheimersche krankheit - Google Patents
Diagnostischer test für die alzheimersche krankheitInfo
- Publication number
- ATE323781T1 ATE323781T1 AT98946146T AT98946146T ATE323781T1 AT E323781 T1 ATE323781 T1 AT E323781T1 AT 98946146 T AT98946146 T AT 98946146T AT 98946146 T AT98946146 T AT 98946146T AT E323781 T1 ATE323781 T1 AT E323781T1
- Authority
- AT
- Austria
- Prior art keywords
- ache
- glycosylation pattern
- sample
- alzheimer
- disease
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 4
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 102000012440 Acetylcholinesterase Human genes 0.000 abstract 5
- 108010022752 Acetylcholinesterase Proteins 0.000 abstract 5
- 229940022698 acetylcholinesterase Drugs 0.000 abstract 5
- 230000013595 glycosylation Effects 0.000 abstract 4
- 238000006206 glycosylation reaction Methods 0.000 abstract 4
- 108010046516 Wheat Germ Agglutinins Proteins 0.000 abstract 3
- 108010062580 Concanavalin A Proteins 0.000 abstract 2
- HBOMLICNUCNMMY-KJFJCRTCSA-N 1-[(4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1NC(=O)C(C)=CN1C1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-KJFJCRTCSA-N 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/827—Actinoplanes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPO9432A AUPO943297A0 (en) | 1997-09-24 | 1997-09-24 | Diagnostic test for alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE323781T1 true ATE323781T1 (de) | 2006-05-15 |
Family
ID=3803714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98946146T ATE323781T1 (de) | 1997-09-24 | 1998-09-24 | Diagnostischer test für die alzheimersche krankheit |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6461831B1 (https=) |
| EP (1) | EP1017845B1 (https=) |
| JP (1) | JP2001517456A (https=) |
| AT (1) | ATE323781T1 (https=) |
| AU (1) | AUPO943297A0 (https=) |
| BR (1) | BR9813015A (https=) |
| CA (1) | CA2304949A1 (https=) |
| DE (1) | DE69834263D1 (https=) |
| HU (1) | HUP0003684A3 (https=) |
| IL (1) | IL135211A0 (https=) |
| WO (1) | WO1999015695A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL130225A0 (en) | 1999-05-31 | 2000-06-01 | Yissum Res Dev Co | Novel uses of antibodies against ache and peptides thereof |
| US20020150878A1 (en) * | 2001-01-23 | 2002-10-17 | Small David Henry | Method for the diagnosis of Alzheimer's Disease and other prion related disorders |
| JP2006515927A (ja) * | 2002-12-20 | 2006-06-08 | モメンタ ファーマシューティカルズ インコーポレイテッド | 疾患を診断および監視するためのグリカンマーカー |
| GB2404734A (en) * | 2003-08-05 | 2005-02-09 | Secr Defence | A method of screening a sample for abnormally glycosylated and/or expressed proteins |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| JP2007513337A (ja) * | 2003-11-19 | 2007-05-24 | サトリス， インコーポレイテッド | アルツハイマー病の診断方法、層化方法およびモニタリング方法 |
| US20050272643A1 (en) * | 2004-06-08 | 2005-12-08 | Windber Research Institute | Removal of serum albumin from human serum or plasma |
| US7851172B2 (en) | 2006-07-25 | 2010-12-14 | University Of Kentucky Research Foundation | Biomarkers of mild cognitive impairment and alzheimer's disease |
| US20100124756A1 (en) * | 2008-10-10 | 2010-05-20 | Sandip Ray | Collection of biomarkers for diagnosis and monitoring of alzheimer's disease in body fluids |
| US20110237537A1 (en) * | 2009-05-29 | 2011-09-29 | Lombard Jay L | Methods for assessment and treatment of mood disorders via single nucleotide polymorphisms analysis |
| US8355927B2 (en) | 2010-11-05 | 2013-01-15 | Genomind, Llc | Neuropsychiatric test reports |
| US9493834B2 (en) | 2009-07-29 | 2016-11-15 | Pharnext | Method for detecting a panel of biomarkers |
| US20110202284A1 (en) * | 2010-02-10 | 2011-08-18 | Mcreynolds Cristopher | Novel groups of biomarkers for diagnosing alzheimer's disease |
| ES2395063B1 (es) * | 2011-03-04 | 2014-02-07 | Universidad Miguel Hernández De Elche | Método para determinar la enfermedad de Alzheimer mediante la detección de glicoproteínas portadoras del glicoepítopo HNK-1 |
| CA2877975C (en) | 2012-04-13 | 2021-09-21 | Oasis Diagnostics Corporation | Specific salivary biomarkers for risk detection, early diagnosis, prognosis and monitoring of alzheimer's and parkinson's diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595883A (en) * | 1990-06-01 | 1997-01-21 | E. R. Squibb & Sons, Inc. | Method of diagnosing alzheimer's disease by measuring acetylcholinesterase activity in ocular fluid |
| CA2048700A1 (en) | 1990-09-04 | 1992-03-05 | Dasakumar S. Navaratnam | Method for diagnosing senile dementia of the alzheimer type |
| US5200324A (en) * | 1990-09-04 | 1993-04-06 | E. R. Squibb & Sons, Inc. | Method of diagnosing senile dementia of the Alzheimer type |
-
1997
- 1997-09-24 AU AUPO9432A patent/AUPO943297A0/en not_active Abandoned
-
1998
- 1998-09-24 WO PCT/AU1998/000809 patent/WO1999015695A1/en not_active Ceased
- 1998-09-24 HU HU0003684A patent/HUP0003684A3/hu unknown
- 1998-09-24 AT AT98946146T patent/ATE323781T1/de not_active IP Right Cessation
- 1998-09-24 CA CA002304949A patent/CA2304949A1/en not_active Abandoned
- 1998-09-24 EP EP98946146A patent/EP1017845B1/en not_active Expired - Lifetime
- 1998-09-24 IL IL13521198A patent/IL135211A0/xx unknown
- 1998-09-24 DE DE69834263T patent/DE69834263D1/de not_active Expired - Lifetime
- 1998-09-24 US US09/509,203 patent/US6461831B1/en not_active Expired - Fee Related
- 1998-09-24 JP JP2000512983A patent/JP2001517456A/ja active Pending
- 1998-09-24 BR BR9813015-3A patent/BR9813015A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999015695A1 (en) | 1999-04-01 |
| CA2304949A1 (en) | 1999-04-01 |
| EP1017845B1 (en) | 2006-04-19 |
| EP1017845A1 (en) | 2000-07-12 |
| JP2001517456A (ja) | 2001-10-09 |
| HUP0003684A2 (hu) | 2001-02-28 |
| US6461831B1 (en) | 2002-10-08 |
| EP1017845A4 (en) | 2003-07-02 |
| DE69834263D1 (de) | 2006-05-24 |
| IL135211A0 (en) | 2001-05-20 |
| AUPO943297A0 (en) | 1997-10-16 |
| BR9813015A (pt) | 2000-08-15 |
| HUP0003684A3 (en) | 2003-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |