CA2301175C - Collagen mimics - Google Patents

Collagen mimics Download PDF

Info

Publication number
CA2301175C
CA2301175C CA2301175A CA2301175A CA2301175C CA 2301175 C CA2301175 C CA 2301175C CA 2301175 A CA2301175 A CA 2301175A CA 2301175 A CA2301175 A CA 2301175A CA 2301175 C CA2301175 C CA 2301175C
Authority
CA
Canada
Prior art keywords
collagen
xaa
stability
triple
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2301175A
Other languages
English (en)
French (fr)
Other versions
CA2301175A1 (en
Inventor
Ronald T. Raines
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of CA2301175A1 publication Critical patent/CA2301175A1/en
Application granted granted Critical
Publication of CA2301175C publication Critical patent/CA2301175C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
CA2301175A 1997-08-25 1998-07-09 Collagen mimics Expired - Lifetime CA2301175C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/918,223 1997-08-25
US08/918,223 US5973112A (en) 1997-08-25 1997-08-25 Collagen mimics
PCT/US1998/014284 WO1999010381A1 (en) 1997-08-25 1998-07-09 Collagen mimics

Publications (2)

Publication Number Publication Date
CA2301175A1 CA2301175A1 (en) 1999-03-04
CA2301175C true CA2301175C (en) 2010-01-26

Family

ID=25440014

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2301175A Expired - Lifetime CA2301175C (en) 1997-08-25 1998-07-09 Collagen mimics

Country Status (8)

Country Link
US (1) US5973112A (https=)
EP (1) EP1007568B1 (https=)
JP (1) JP4514328B2 (https=)
AT (1) ATE371672T1 (https=)
AU (1) AU8480698A (https=)
CA (1) CA2301175C (https=)
DE (1) DE69838331T2 (https=)
WO (1) WO1999010381A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2452593C (en) * 2001-07-12 2015-02-03 Arexis Ab Triple polypeptide complexes
JP5070442B2 (ja) * 2002-02-28 2012-11-14 株式会社Phg 新規なポリペプチドおよびその製造方法
WO2005000872A2 (en) * 2003-06-23 2005-01-06 Wisconsin Alumni Research Foundation Collagen mimics
WO2005078085A1 (ja) * 2004-02-16 2005-08-25 Techno Network Shikoku Co., Ltd. コラーゲン様構造を有するポリペプチド
JP5601437B2 (ja) * 2004-02-16 2014-10-08 株式会社テクノネットワーク四国 コラーゲン様構造を有するポリペプチド
US9758569B2 (en) * 2006-05-26 2017-09-12 Wisconsin Alumni Research Foundation Collagen mimics
CN101072380B (zh) * 2007-06-08 2010-12-08 华为技术有限公司 内容下发方法及系统、网络设备、移动数据业务管理平台
US20090299034A1 (en) * 2007-08-01 2009-12-03 Mabel Alamino Cejas Collagen-related peptides
CA2695288A1 (en) 2007-08-01 2009-02-05 Ethicon, Inc. Collagen-related peptides and uses thereof
US7858741B2 (en) * 2008-02-06 2010-12-28 Wisconsin Alumni Research Foundation Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues
US20100021527A1 (en) * 2008-07-25 2010-01-28 Chunlin Yang Collagen-related peptides and uses thereof and hemostatic foam substrates
BR112019021056B1 (pt) 2017-04-06 2022-11-22 Sustain Holdings, Llc Usos de uma composição que compreende um peptídeo mimético de colágeno para o tratamento ou a prevenção de uma doença, distúrbio ou ferida ocular
EP3958889B1 (en) 2019-04-22 2025-01-08 Sustain Holdings, LLC Collagen mimetic peptide compositions for treating a posterior segment ocular disease or disorder involving the retina, retinal blood vessels, retinal nerves or optic nerve
CN117903293B (zh) * 2024-03-19 2025-01-07 如凤凰再生科技发展(成都)有限公司 一种具有热稳定性和促进自身胶原生成的三螺旋胶原蛋白及其制备方法和用途
CN119019539B (zh) * 2024-09-04 2025-07-18 上海欣肽生物科技有限公司 一种长链类胶原蛋白多肽的迭代指数合成方法

Also Published As

Publication number Publication date
EP1007568B1 (en) 2007-08-29
DE69838331T2 (de) 2008-05-21
EP1007568A1 (en) 2000-06-14
ATE371672T1 (de) 2007-09-15
DE69838331D1 (de) 2007-10-11
WO1999010381A1 (en) 1999-03-04
US5973112A (en) 1999-10-26
CA2301175A1 (en) 1999-03-04
JP2001514189A (ja) 2001-09-11
JP4514328B2 (ja) 2010-07-28
AU8480698A (en) 1999-03-16

Similar Documents

Publication Publication Date Title
CA2301175C (en) Collagen mimics
US5948887A (en) Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
Holmgren et al. A hyperstable collagen mimic
Brodsky et al. The collagen triple-helix structure
Foo et al. Genetic engineering of fibrous proteins: spider dragline silk and collagen
US11390662B2 (en) Collagen mimics
JP5583695B2 (ja) コラーゲン関連ペプチド及びその使用並びに止血発泡体基材
WO1998043686A1 (en) Enzyme-mediated modification of fibrin for tissue engineering
WO2009018126A2 (en) Collagen-related peptides and uses thereof
JPH03118331A (ja) 環状フイブリノーゲンレセプター拮抗薬
US20090264626A1 (en) Stabilization of the collagen triple helix by o-methylation of hydroxyproline residues
CA2009390A1 (en) Viper venom polypeptides and variants
Kalita et al. Hierarchical assemblies of collagen-mimetic peptides: From a fundamental understanding to developing biomaterials
US20040082513A1 (en) Enzyme-mediated modification of fibrin for tissue engineering
AU2003200660B2 (en) Collagen Mimics
US6100044A (en) Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
EP0412115A4 (en) Hybrid peptides and methods of their use
JPH06510987A (ja) キニノーゲン重鎖のカルパイン抑制性ペプチド同族体
US7122521B2 (en) Collagen mimics
KR101036054B1 (ko) 단백질 폴리펩티드로부터 유도된 아실 리포아미노산류 및 리포펩티드류를 선택적으로 분리 정제하는 방법
Yu Advancing Collagen Mimicry: Covalent Triple Helix Stabilization and Higher-order Nanostructure Design
Hartgerink Advancing Collagen Mimicry: Covalent Triple Helix Stabilization and Higher-order Nanostructure Design
Dai I. Collagen-like polypeptides. II. Helix-turn-helix peptides and turn mimetics
CA2009613A1 (en) Polypeptide synthesis
AU2008282500B2 (en) Collagen-related peptides and uses thereof

Legal Events

Date Code Title Description
EEER Examination request