CA2298061A1 - Compositions polynucleotidiques - Google Patents

Compositions polynucleotidiques Download PDF

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Publication number
CA2298061A1
CA2298061A1 CA002298061A CA2298061A CA2298061A1 CA 2298061 A1 CA2298061 A1 CA 2298061A1 CA 002298061 A CA002298061 A CA 002298061A CA 2298061 A CA2298061 A CA 2298061A CA 2298061 A1 CA2298061 A1 CA 2298061A1
Authority
CA
Canada
Prior art keywords
polymer
monomer
polynucleotide
segment
copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002298061A
Other languages
English (en)
Inventor
Alexnader V. Kabanov
Valery Y. Alakov
Sergey V. Vinogradov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Supratek Pharma Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/912,968 external-priority patent/US6353055B1/en
Priority claimed from US09/124,943 external-priority patent/US6221959B1/en
Application filed by Individual filed Critical Individual
Publication of CA2298061A1 publication Critical patent/CA2298061A1/fr
Abandoned legal-status Critical Current

Links

Abstract

L'invention concerne des compositions visant à stabiliser des acides polynucléiques et à accroître leur capacité à traverser les membranes des cellules pour agir à l'intérieur de celles-ci. Selon un aspect de l'invention, on obtient un complexe polynucléotidique à partir d'un polynucléotide et de certains copolymères séquencés de polyéther. Ce complexe polynucléotidique peut également renfermer un polymère polycationique, ainsi que des molécules cibles et des tensioactifs appropriés. L'invention concerne enfin un complexe polynucléotidique constitué à partir d'un polynucléotide et d'un copolymère séquencé comprenant une séquence polyéther et une séquence polycation.
CA002298061A 1997-08-01 1998-07-31 Compositions polynucleotidiques Abandoned CA2298061A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/912,968 US6353055B1 (en) 1994-11-18 1997-08-01 Polynucleotide compositions
US08/912,968 1997-08-01
US09/124,943 1998-07-30
US09/124,943 US6221959B1 (en) 1994-11-18 1998-07-30 Polynucleotide compositions
PCT/US1998/016012 WO1999006055A1 (fr) 1997-08-01 1998-07-31 Compositions polynucleotidiques

Publications (1)

Publication Number Publication Date
CA2298061A1 true CA2298061A1 (fr) 1999-02-11

Family

ID=26823120

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002298061A Abandoned CA2298061A1 (fr) 1997-08-01 1998-07-31 Compositions polynucleotidiques

Country Status (3)

Country Link
EP (1) EP1003527A4 (fr)
JP (1) JP2003526692A (fr)
CA (1) CA2298061A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249476A (zh) * 2020-02-19 2020-06-09 深圳厚存纳米药业有限公司 泊洛沙姆和/或泊洛沙胺与脂质组合中性复合物纳米粒

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006131591A (ja) * 2004-11-09 2006-05-25 National Cardiovascular Center 医薬組成物及び該組成物による遺伝子治療方法
JP4870941B2 (ja) * 2005-05-09 2012-02-08 公立大学法人大阪府立大学 高分子化合物
KR101388320B1 (ko) * 2005-12-15 2014-04-22 뽈리쁠뤼스-트랑스펙씨옹 양이온성 올리고뉴클레오티드, 이를 제조하기 위한 자동화방법 및 이의 용도
US9271929B2 (en) * 2008-11-25 2016-03-01 École Polytechnique Fédérale De Lausanne (Epfl) Block copolymers and uses thereof
EP3034539A1 (fr) * 2014-12-19 2016-06-22 Ethris GmbH Compositions pour l'introduction d'acides nucléiques dans des cellules

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656611A (en) * 1994-11-18 1997-08-12 Supratek Pharma Inc. Polynucleotide compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249476A (zh) * 2020-02-19 2020-06-09 深圳厚存纳米药业有限公司 泊洛沙姆和/或泊洛沙胺与脂质组合中性复合物纳米粒
CN111249476B (zh) * 2020-02-19 2023-09-26 深圳厚存纳米药业有限公司 泊洛沙姆和/或泊洛沙胺与脂质组合中性复合物纳米粒

Also Published As

Publication number Publication date
EP1003527A4 (fr) 2003-07-16
EP1003527A1 (fr) 2000-05-31
JP2003526692A (ja) 2003-09-09

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued