CA2281096A1 - Method of using neurotrophic carbamates and ureas - Google Patents
Method of using neurotrophic carbamates and ureas Download PDFInfo
- Publication number
- CA2281096A1 CA2281096A1 CA002281096A CA2281096A CA2281096A1 CA 2281096 A1 CA2281096 A1 CA 2281096A1 CA 002281096 A CA002281096 A CA 002281096A CA 2281096 A CA2281096 A CA 2281096A CA 2281096 A1 CA2281096 A1 CA 2281096A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- straight
- neurological disorder
- branched alkyl
- neurodegeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80564697A | 1997-02-27 | 1997-02-27 | |
US08/805,646 | 1997-02-27 | ||
PCT/US1998/003485 WO1998037882A1 (en) | 1997-02-27 | 1998-02-26 | Method of using neurotrophic carbamates and ureas |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2281096A1 true CA2281096A1 (en) | 1998-09-03 |
Family
ID=25192108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002281096A Abandoned CA2281096A1 (en) | 1997-02-27 | 1998-02-26 | Method of using neurotrophic carbamates and ureas |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1001762A4 (xx) |
JP (1) | JP2001513772A (xx) |
AR (1) | AR011869A1 (xx) |
AU (1) | AU6181698A (xx) |
CA (1) | CA2281096A1 (xx) |
PA (1) | PA8447901A1 (xx) |
PE (1) | PE46599A1 (xx) |
WO (1) | WO1998037882A1 (xx) |
ZA (1) | ZA98825B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6218424B1 (en) * | 1996-09-25 | 2001-04-17 | Gpi Nil Holdings, Inc. | Heterocyclic ketone and thioester compounds and uses |
US6242468B1 (en) * | 1997-02-27 | 2001-06-05 | Jia-He Li | Carbamate and urea compositions and neurotrophic uses |
AU756912B2 (en) | 1998-07-17 | 2003-01-23 | Agouron Pharmaceuticals, Inc. | Compounds, compositions, and methods for stimulating neuronal growth and elongation |
US6395758B1 (en) * | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
US7338976B1 (en) * | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
US6323215B1 (en) | 1999-07-09 | 2001-11-27 | Ortho-Mcneil Pharmaceutical, Inc. | Neurotrophic tetrahydroisoquinolines and tetrahydrothienopyridines, and related compositions and methods |
JP2003504367A (ja) | 1999-07-09 | 2003-02-04 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 神経栄養性ピロリジン類およびピペリジン類、並びに関連組成物および方法 |
WO2001004091A1 (en) | 1999-07-09 | 2001-01-18 | Ortho-Mcneil Pharmaceutical, Inc. | Neurotrophic 2-azetidinecarboxylic acid derivatives, and related compositions and methods |
CA2383086A1 (en) * | 1999-09-08 | 2001-03-15 | Joseph P. Steiner | Non-peptidic cyclophilin binding compounds and their use |
GT200000203A (es) | 1999-12-01 | 2002-05-24 | Compuestos, composiciones y metodos para estimular el crecimiento y elongacion de neuronas. | |
EP1339668A2 (en) * | 2000-11-28 | 2003-09-03 | Guilford Pharmaceuticals Inc. | Bisubstituted carbocyclic cyclophilin binding compounds and theirus |
US6656971B2 (en) * | 2001-01-25 | 2003-12-02 | Guilford Pharmaceuticals Inc. | Trisubstituted carbocyclic cyclophilin binding compounds and their use |
EP1402888A1 (en) * | 2002-09-18 | 2004-03-31 | Jerini AG | The use of substituted carbocyclic compounds as rotamases inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5620971A (en) * | 1991-05-09 | 1997-04-15 | Vertex Pharmaceuticals Incorporated | Biologically active acylated amino acid derivatives |
US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
US6037370A (en) * | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
US5780484A (en) * | 1996-11-13 | 1998-07-14 | Vertex Pharmaceuticals Incorporated | Methods for stimulating neurite growth with piperidine compounds |
-
1998
- 1998-02-02 ZA ZA98825A patent/ZA98825B/xx unknown
- 1998-02-19 PE PE1998000117A patent/PE46599A1/es not_active Application Discontinuation
- 1998-02-25 AR ARP980100829A patent/AR011869A1/es not_active Application Discontinuation
- 1998-02-26 WO PCT/US1998/003485 patent/WO1998037882A1/en not_active Application Discontinuation
- 1998-02-26 CA CA002281096A patent/CA2281096A1/en not_active Abandoned
- 1998-02-26 EP EP98906647A patent/EP1001762A4/en not_active Withdrawn
- 1998-02-26 AU AU61816/98A patent/AU6181698A/en not_active Abandoned
- 1998-02-26 PA PA19988447901A patent/PA8447901A1/es unknown
- 1998-02-26 JP JP53775298A patent/JP2001513772A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AR011869A1 (es) | 2000-09-13 |
WO1998037882A1 (en) | 1998-09-03 |
PE46599A1 (es) | 1999-05-12 |
EP1001762A1 (en) | 2000-05-24 |
PA8447901A1 (es) | 2000-05-24 |
ZA98825B (en) | 1998-10-19 |
EP1001762A4 (en) | 2002-05-08 |
JP2001513772A (ja) | 2001-09-04 |
AU6181698A (en) | 1998-09-18 |
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CA2281096A1 (en) | Method of using neurotrophic carbamates and ureas | |
US7056935B2 (en) | Rotamase enzyme activity inhibitors | |
US6242468B1 (en) | Carbamate and urea compositions and neurotrophic uses | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |