CA2280960C - Oxirancarboxylic acids for the treatment of diabetes - Google Patents
Oxirancarboxylic acids for the treatment of diabetes Download PDFInfo
- Publication number
- CA2280960C CA2280960C CA002280960A CA2280960A CA2280960C CA 2280960 C CA2280960 C CA 2280960C CA 002280960 A CA002280960 A CA 002280960A CA 2280960 A CA2280960 A CA 2280960A CA 2280960 C CA2280960 C CA 2280960C
- Authority
- CA
- Canada
- Prior art keywords
- substituted
- condition
- formula
- lower alkyl
- het
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19705718A DE19705718A1 (de) | 1997-02-14 | 1997-02-14 | Neue Oxirancarbonsäuren zur Behandlung des Diabetes Typ 2 und anderer insulinresistenter Zustände |
| DE19705718.7 | 1997-02-14 | ||
| PCT/EP1998/000611 WO1998035952A1 (de) | 1997-02-14 | 1998-02-05 | Oxirancarbonsäuren für die behandlung von diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2280960A1 CA2280960A1 (en) | 1998-08-20 |
| CA2280960C true CA2280960C (en) | 2007-04-17 |
Family
ID=7820279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002280960A Expired - Fee Related CA2280960C (en) | 1997-02-14 | 1998-02-05 | Oxirancarboxylic acids for the treatment of diabetes |
Country Status (10)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8013014B2 (en) * | 2002-07-05 | 2011-09-06 | Georgia Tech Research Corporation | Aza-peptide epoxides |
| US7056947B2 (en) * | 2002-07-05 | 2006-06-06 | Georgia Tech Research Corp. | Aza-peptide epoxides |
| WO2004071458A2 (en) | 2003-02-13 | 2004-08-26 | Albert Einstein College Of Medicine Of Yeshiva University | REGULATION OF FOOD INTAKE AND GLUCOSE PRODUCTION BY MODULATION OF LONG-CHAIN FATTY ACYL-CoA LEVELS IN THE HYPOTHALAMUS |
| AU2005214388A1 (en) * | 2004-02-18 | 2005-09-01 | Georgia Tech Research Corporation | Propenoyl hydrazides |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0025192B1 (de) * | 1979-09-07 | 1983-05-11 | Byk Gulden Lomberg Chemische Fabrik GmbH | Substituierte Oxirancarbonsäuren, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel |
| US4337267A (en) | 1980-08-25 | 1982-06-29 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phenalkoxyalkyl- and phenoxyalkyl-substituted oxiranecarboxylic acids, their use and medicaments containing them |
| JPS58501124A (ja) * | 1981-07-24 | 1983-07-14 | ビイク グルデン ロンベルク ヒエ−ミツシエ フアブリ−ク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | フエニルアルキルオキシランカルボン酸、その製法、その使用及びそれを含有する医薬品 |
| WO1987000751A2 (en) * | 1985-08-02 | 1987-02-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Use of oxirancarboxylic acids for the treatment of hyperlipemia |
| US4788306A (en) * | 1987-04-03 | 1988-11-29 | American Home Products Corporation | Fluorooxirane carboxylates as hypoglycemic agents |
| US4788304A (en) * | 1987-12-07 | 1988-11-29 | American Home Products Corporation | Phospholipase A2 inhibitors |
| GB9209628D0 (en) * | 1992-05-05 | 1992-06-17 | Smithkline Beecham Plc | Compounds |
| WO1998000422A1 (en) * | 1996-07-02 | 1998-01-08 | Sang Sup Jew | Oxirane carboxylic acid derivative and its manufacturing method |
-
1997
- 1997-02-14 DE DE19705718A patent/DE19705718A1/de not_active Withdrawn
-
1998
- 1998-02-05 WO PCT/EP1998/000611 patent/WO1998035952A1/de active IP Right Grant
- 1998-02-05 AT AT98909391T patent/ATE258550T1/de not_active IP Right Cessation
- 1998-02-05 PT PT98909391T patent/PT966455E/pt unknown
- 1998-02-05 CA CA002280960A patent/CA2280960C/en not_active Expired - Fee Related
- 1998-02-05 EP EP98909391A patent/EP0966455B1/de not_active Expired - Lifetime
- 1998-02-05 JP JP53529998A patent/JP3357378B2/ja not_active Expired - Fee Related
- 1998-02-05 AU AU63946/98A patent/AU6394698A/en not_active Abandoned
- 1998-02-05 DK DK98909391T patent/DK0966455T3/da active
- 1998-02-05 DE DE59810675T patent/DE59810675D1/de not_active Expired - Lifetime
- 1998-02-05 US US09/367,383 patent/US6479676B1/en not_active Expired - Lifetime
-
2002
- 2002-06-18 US US10/173,444 patent/US6670481B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU6394698A (en) | 1998-09-08 |
| EP0966455B1 (de) | 2004-01-28 |
| DK0966455T3 (da) | 2004-05-17 |
| JP2000509726A (ja) | 2000-08-02 |
| US6479676B1 (en) | 2002-11-12 |
| EP0966455A1 (de) | 1999-12-29 |
| JP3357378B2 (ja) | 2002-12-16 |
| US6670481B2 (en) | 2003-12-30 |
| PT966455E (pt) | 2004-08-31 |
| ATE258550T1 (de) | 2004-02-15 |
| DE59810675D1 (de) | 2004-03-04 |
| DE19705718A1 (de) | 1998-08-20 |
| US20020198382A1 (en) | 2002-12-26 |
| CA2280960A1 (en) | 1998-08-20 |
| WO1998035952A1 (de) | 1998-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20130205 |