CA2276018C - Spray chamber with dryer - Google Patents
Spray chamber with dryer Download PDFInfo
- Publication number
- CA2276018C CA2276018C CA002276018A CA2276018A CA2276018C CA 2276018 C CA2276018 C CA 2276018C CA 002276018 A CA002276018 A CA 002276018A CA 2276018 A CA2276018 A CA 2276018A CA 2276018 C CA2276018 C CA 2276018C
- Authority
- CA
- Canada
- Prior art keywords
- spray
- gas
- nebulizer
- droplets
- sheath gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007921 spray Substances 0.000 title claims abstract description 263
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000012528 membrane Substances 0.000 claims abstract description 15
- 238000001035 drying Methods 0.000 claims abstract description 13
- 239000002904 solvent Substances 0.000 claims abstract description 9
- 239000002699 waste material Substances 0.000 claims abstract description 8
- 238000005054 agglomeration Methods 0.000 claims abstract description 6
- 230000002776 aggregation Effects 0.000 claims abstract description 6
- 230000002093 peripheral effect Effects 0.000 claims abstract 6
- 239000007789 gas Substances 0.000 claims description 184
- 239000006199 nebulizer Substances 0.000 claims description 117
- 239000007788 liquid Substances 0.000 claims description 48
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 26
- 229910052786 argon Inorganic materials 0.000 claims description 17
- 238000010438 heat treatment Methods 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 5
- 230000003134 recirculating effect Effects 0.000 claims description 5
- AUUAIQGEFIEHRO-UHFFFAOYSA-N 1,1,2,2-tetrafluoro-2-[1,1,1,2,3,3-hexafluoro-3-(1,2,2-trifluoroethenoxy)propan-2-yl]oxyethanesulfonic acid Chemical compound OS(=O)(=O)C(F)(F)C(F)(F)OC(F)(C(F)(F)F)C(F)(F)OC(F)=C(F)F AUUAIQGEFIEHRO-UHFFFAOYSA-N 0.000 claims description 2
- 238000011068 loading method Methods 0.000 abstract description 3
- 230000001737 promoting effect Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 description 58
- 239000000443 aerosol Substances 0.000 description 17
- 230000004044 response Effects 0.000 description 14
- 230000003446 memory effect Effects 0.000 description 11
- 239000012491 analyte Substances 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 229920000557 Nafion® Polymers 0.000 description 7
- 239000002245 particle Substances 0.000 description 7
- 239000011159 matrix material Substances 0.000 description 6
- 239000010948 rhodium Substances 0.000 description 6
- 238000002156 mixing Methods 0.000 description 5
- 229910052703 rhodium Inorganic materials 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 4
- 238000005755 formation reaction Methods 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 239000003595 mist Substances 0.000 description 4
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 description 4
- 238000005507 spraying Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000009833 condensation Methods 0.000 description 3
- 230000005494 condensation Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 239000012488 sample solution Substances 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000283153 Cetacea Species 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000003416 augmentation Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 229910000420 cerium oxide Inorganic materials 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000004807 desolvation Methods 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000002663 nebulization Methods 0.000 description 2
- BMMGVYCKOGBVEV-UHFFFAOYSA-N oxo(oxoceriooxy)cerium Chemical compound [Ce]=O.O=[Ce]=O BMMGVYCKOGBVEV-UHFFFAOYSA-N 0.000 description 2
- 229910052684 Cerium Inorganic materials 0.000 description 1
- 229920000544 Gore-Tex Polymers 0.000 description 1
- 241000167880 Hirundinidae Species 0.000 description 1
- 241000238634 Libellulidae Species 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004581 coalescence Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 235000012489 doughnuts Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000009616 inductively coupled plasma Methods 0.000 description 1
- 238000005040 ion trap Methods 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000010408 sweeping Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229910052716 thallium Inorganic materials 0.000 description 1
- BKVIYDNLLOSFOA-UHFFFAOYSA-N thallium Chemical compound [Tl] BKVIYDNLLOSFOA-UHFFFAOYSA-N 0.000 description 1
- 230000001550 time effect Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
- H01J49/049—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for applying heat to desorb the sample; Evaporation
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
- H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
- H01J49/045—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol with means for using a nebulising gas, i.e. pneumatically assisted
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/105—Ion sources; Ion guns using high-frequency excitation, e.g. microwave excitation, Inductively Coupled Plasma [ICP]
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77859397A | 1997-01-03 | 1997-01-03 | |
| US08/778,593 | 1997-01-03 | ||
| US08/974,957 | 1997-11-20 | ||
| US08/974,957 US5969352A (en) | 1997-01-03 | 1997-11-20 | Spray chamber with dryer |
| PCT/CA1997/001007 WO1998029896A1 (en) | 1997-01-03 | 1997-12-22 | Spray chamber with dryer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2276018A1 CA2276018A1 (en) | 1998-07-09 |
| CA2276018C true CA2276018C (en) | 2004-11-23 |
Family
ID=27119475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002276018A Expired - Lifetime CA2276018C (en) | 1997-01-03 | 1997-12-22 | Spray chamber with dryer |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1012871A1 (de) |
| JP (1) | JP3831415B2 (de) |
| AU (1) | AU5474598A (de) |
| CA (1) | CA2276018C (de) |
| WO (1) | WO1998029896A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7045015B2 (en) | 1998-09-30 | 2006-05-16 | Optomec Design Company | Apparatuses and method for maskless mesoscale material deposition |
| JP3902380B2 (ja) * | 2000-05-19 | 2007-04-04 | エスアイアイ・ナノテクノロジー株式会社 | Ｉｃｐ分析装置 |
| JP2004534241A (ja) * | 2001-07-03 | 2004-11-11 | ヴァリアン オーストラリア ピーティーワイ．エルティーディー． | プラズマトーチ |
| US7479630B2 (en) * | 2004-03-25 | 2009-01-20 | Bandura Dmitry R | Method and apparatus for flow cytometry linked with elemental analysis |
| DE102005004804B4 (de) * | 2004-02-06 | 2010-06-10 | Micromass Uk Ltd. | Ionenquelle und Verfahren zur Ionisierung einer Probe |
| US7294841B2 (en) | 2004-02-06 | 2007-11-13 | Micromass Uk Limited | Mass spectrometer |
| US7265362B2 (en) | 2004-02-06 | 2007-09-04 | Micromass Uk Limited | Mass spectrometer |
| US7938341B2 (en) * | 2004-12-13 | 2011-05-10 | Optomec Design Company | Miniature aerosol jet and aerosol jet array |
| US7674671B2 (en) | 2004-12-13 | 2010-03-09 | Optomec Design Company | Aerodynamic jetting of aerosolized fluids for fabrication of passive structures |
| TWI482662B (zh) | 2007-08-30 | 2015-05-01 | Optomec Inc | 機械上一體式及緊密式耦合之列印頭以及噴霧源 |
| JP4982900B2 (ja) * | 2008-07-02 | 2012-07-25 | 独立行政法人産業技術総合研究所 | 脱溶媒機能付き誘導結合プラズマトーチ |
| KR200457166Y1 (ko) | 2008-12-16 | 2011-12-07 | 문무 주식회사 | 분말 건조 장치 |
| SG10201501031YA (en) | 2010-02-26 | 2015-04-29 | Perkinelmer Health Sci Inc | Fluid chromatography injectors and injector inserts |
| AU2011220352B2 (en) | 2010-02-26 | 2015-10-22 | Perkinelmer U.S. Llc | Plasma mass spectrometry with ion suppression |
| US9190253B2 (en) | 2010-02-26 | 2015-11-17 | Perkinelmer Health Sciences, Inc. | Systems and methods of suppressing unwanted ions |
| GB201216412D0 (en) * | 2012-09-14 | 2012-10-31 | Shimadzu Corp | Apparatus for providing gaseous sample ions/molecules and a corresponding method |
| JP2014211377A (ja) * | 2013-04-19 | 2014-11-13 | 株式会社堀場製作所 | 粒子分析装置 |
| WO2016130709A1 (en) | 2015-02-10 | 2016-08-18 | Optomec, Inc. | Fabrication of three-dimensional structures by in-flight curing of aerosols |
| JP6048552B1 (ja) | 2015-08-21 | 2016-12-21 | 株式会社 イアス | オンライン移送した分析試料の分析システム |
| JP6889772B2 (ja) * | 2016-05-18 | 2021-06-18 | パーキンエルマー・ヘルス・サイエンシーズ・カナダ・インコーポレイテッドＰｅｒｋｉｎｅｌｍｅｒ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ Ｃａｎａｄａ， Ｉｎｃ． | 噴霧チャンバ及びそれらを利用する方法 |
| CN110603441B (zh) * | 2017-05-12 | 2022-06-03 | 胜高股份有限公司 | 喷雾室、试样雾化导入装置、分析装置和试样中的成分分析方法 |
| KR20200087196A (ko) | 2017-11-13 | 2020-07-20 | 옵토멕 인코포레이티드 | 에어로졸 스트림의 셔터링 |
| EP3921086A4 (de) | 2019-02-04 | 2022-11-02 | Glass Expansion Pty. Limited | Analytischer vernebler |
| CN116726519A (zh) * | 2023-06-14 | 2023-09-12 | 广东省麦思科学仪器创新研究院 | 雾化气细胞干燥装置和质谱流式细胞仪 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4990740A (en) * | 1989-03-06 | 1991-02-05 | The Dow Chemical Company | Intra-microspray ICP torch |
| US4958529A (en) * | 1989-11-22 | 1990-09-25 | Vestec Corporation | Interface for coupling liquid chromatography to solid or gas phase detectors |
| US5122670A (en) * | 1991-05-17 | 1992-06-16 | Finnigan Corporation | Multilayer flow electrospray ion source using improved sheath liquid |
| EP0560537A1 (de) * | 1992-03-10 | 1993-09-15 | Mds Health Group Limited | Vorrichtung und Verfahren zur Einführung von flüssigen Proben |
| CA2062629C (en) * | 1992-03-10 | 1999-06-15 | John Barry French | Apparatus and method for liquid sample introduction |
-
1997
- 1997-12-22 EP EP97951050A patent/EP1012871A1/de not_active Withdrawn
- 1997-12-22 AU AU54745/98A patent/AU5474598A/en not_active Abandoned
- 1997-12-22 JP JP52951298A patent/JP3831415B2/ja not_active Expired - Lifetime
- 1997-12-22 WO PCT/CA1997/001007 patent/WO1998029896A1/en active Application Filing
- 1997-12-22 CA CA002276018A patent/CA2276018C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001507449A (ja) | 2001-06-05 |
| AU5474598A (en) | 1998-07-31 |
| EP1012871A1 (de) | 2000-06-28 |
| JP3831415B2 (ja) | 2006-10-11 |
| CA2276018A1 (en) | 1998-07-09 |
| WO1998029896A1 (en) | 1998-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20171222 |