CA2272927C - Dimesylate salts of neuropeptide y ligands - Google Patents

Dimesylate salts of neuropeptide y ligands Download PDF

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Publication number
CA2272927C
CA2272927C CA002272927A CA2272927A CA2272927C CA 2272927 C CA2272927 C CA 2272927C CA 002272927 A CA002272927 A CA 002272927A CA 2272927 A CA2272927 A CA 2272927A CA 2272927 C CA2272927 C CA 2272927C
Authority
CA
Canada
Prior art keywords
compound
diseases
disorders
neuropeptide
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002272927A
Other languages
English (en)
French (fr)
Other versions
CA2272927A1 (en
Inventor
Alireza S. Kord
Laurie A. Whipple
Douglas J. M. Allen
Lyle R. Brostrom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of CA2272927A1 publication Critical patent/CA2272927A1/en
Application granted granted Critical
Publication of CA2272927C publication Critical patent/CA2272927C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002272927A 1996-11-26 1997-11-19 Dimesylate salts of neuropeptide y ligands Expired - Fee Related CA2272927C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3181596P 1996-11-26 1996-11-26
US60/031,815 1996-11-26
PCT/IB1997/001465 WO1998023603A1 (en) 1996-11-26 1997-11-19 Dimesylate salts of neuropeptide y ligands

Publications (2)

Publication Number Publication Date
CA2272927A1 CA2272927A1 (en) 1998-06-04
CA2272927C true CA2272927C (en) 2003-02-04

Family

ID=21861551

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002272927A Expired - Fee Related CA2272927C (en) 1996-11-26 1997-11-19 Dimesylate salts of neuropeptide y ligands

Country Status (23)

Country Link
US (1) US5914329A (cg-RX-API-DMAC7.html)
EP (1) EP0944611B1 (cg-RX-API-DMAC7.html)
JP (1) JP3120861B2 (cg-RX-API-DMAC7.html)
AP (1) AP9701148A0 (cg-RX-API-DMAC7.html)
AR (1) AR010304A1 (cg-RX-API-DMAC7.html)
AT (1) ATE257472T1 (cg-RX-API-DMAC7.html)
AU (1) AU4792497A (cg-RX-API-DMAC7.html)
BR (1) BR9713538A (cg-RX-API-DMAC7.html)
CA (1) CA2272927C (cg-RX-API-DMAC7.html)
DE (1) DE69727155T2 (cg-RX-API-DMAC7.html)
DK (1) DK0944611T3 (cg-RX-API-DMAC7.html)
ES (1) ES2213207T3 (cg-RX-API-DMAC7.html)
GT (1) GT199700123A (cg-RX-API-DMAC7.html)
HN (1) HN1997000154A (cg-RX-API-DMAC7.html)
HR (1) HRP970640A2 (cg-RX-API-DMAC7.html)
ID (1) ID18964A (cg-RX-API-DMAC7.html)
MA (1) MA26450A1 (cg-RX-API-DMAC7.html)
PA (1) PA8441701A1 (cg-RX-API-DMAC7.html)
PE (1) PE17099A1 (cg-RX-API-DMAC7.html)
PT (1) PT944611E (cg-RX-API-DMAC7.html)
TN (1) TNSN97191A1 (cg-RX-API-DMAC7.html)
WO (1) WO1998023603A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA9710587B (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053477A1 (en) * 2000-01-20 2001-07-26 Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of neuropeptide y activity
EP2002827A2 (en) 2001-12-05 2008-12-17 The Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of sympathetic tone
WO2003057886A2 (en) 2002-01-09 2003-07-17 Arexis Ab Detection of mutations
KR100716389B1 (ko) * 2004-11-23 2007-05-11 동화약품공업주식회사 Ｎ-히드록시－４－｛５－［４－（5－이소프로필－２－메틸－１,３－티아졸－4－일）페녹시］펜톡시｝벤즈아미딘 ２메탄술폰산염
EP1877076A4 (en) * 2005-04-15 2012-02-01 Regenertech Pty Ltd USE OF NEUROPEPTIDES Y (NPY) AND AGONIST OF ANTAGONISTS THEREOF FOR REGENERATING TISSUES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014307A1 (en) * 1994-11-07 1996-05-17 Pfizer Inc. Certain substituted benzylamine derivatives; a new class of neuropeptide y1 specific ligands

Also Published As

Publication number Publication date
DE69727155D1 (de) 2004-02-12
DK0944611T3 (da) 2004-04-13
US5914329A (en) 1999-06-22
DE69727155T2 (de) 2004-07-08
HRP970640A2 (en) 1998-10-31
AP9701148A0 (en) 1998-01-31
EP0944611A1 (en) 1999-09-29
CA2272927A1 (en) 1998-06-04
JP3120861B2 (ja) 2000-12-25
ID18964A (id) 1998-05-28
WO1998023603A1 (en) 1998-06-04
PE17099A1 (es) 1999-02-19
GT199700123A (es) 1999-05-19
ZA9710587B (en) 1999-05-25
ES2213207T3 (es) 2004-08-16
PT944611E (pt) 2004-04-30
MA26450A1 (fr) 2004-12-20
HN1997000154A (es) 1999-02-09
TNSN97191A1 (fr) 2005-03-15
AR010304A1 (es) 2000-06-07
JP2000505110A (ja) 2000-04-25
BR9713538A (cg-RX-API-DMAC7.html) 2000-03-21
EP0944611B1 (en) 2004-01-07
PA8441701A1 (es) 2000-05-24
ATE257472T1 (de) 2004-01-15
AU4792497A (en) 1998-06-22

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