CA2269910A1 - Nouveau procede de preparation de morphinanes - Google Patents

Nouveau procede de preparation de morphinanes Download PDF

Info

Publication number
CA2269910A1
CA2269910A1 CA002269910A CA2269910A CA2269910A1 CA 2269910 A1 CA2269910 A1 CA 2269910A1 CA 002269910 A CA002269910 A CA 002269910A CA 2269910 A CA2269910 A CA 2269910A CA 2269910 A1 CA2269910 A1 CA 2269910A1
Authority
CA
Canada
Prior art keywords
aryl
compound
formula
cyclopropylmethyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002269910A
Other languages
English (en)
Inventor
Zhong-Yong Wei
Helmut Schmidhammer
Peter Schwarz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Zhong-Yong Wei
Helmut Schmidhammer
Astra Aktiebolag
Peter Schwarz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhong-Yong Wei, Helmut Schmidhammer, Astra Aktiebolag, Peter Schwarz filed Critical Zhong-Yong Wei
Publication of CA2269910A1 publication Critical patent/CA2269910A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002269910A 1996-11-19 1996-11-19 Nouveau procede de preparation de morphinanes Abandoned CA2269910A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SE1996/001497 WO1998022467A1 (fr) 1996-11-19 1996-11-19 Nouveau procede de preparation de morphinanes

Publications (1)

Publication Number Publication Date
CA2269910A1 true CA2269910A1 (fr) 1998-05-28

Family

ID=20402270

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002269910A Abandoned CA2269910A1 (fr) 1996-11-19 1996-11-19 Nouveau procede de preparation de morphinanes

Country Status (5)

Country Link
EP (1) EP0946564A1 (fr)
JP (1) JP2001504829A (fr)
AU (1) AU1402497A (fr)
CA (1) CA2269910A1 (fr)
WO (1) WO1998022467A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19939044A1 (de) * 1999-08-18 2001-03-15 Gruenenthal Gmbh Verwendung von Morphinanderivaten als Arzneimittel
AU2011263417B2 (en) * 2010-06-11 2014-03-27 Rhodes Technologies Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof
US10800516B2 (en) 2017-06-02 2020-10-13 The Boeing Company Semi-levered shrink landing gear

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3412727A1 (de) * 1984-04-04 1985-10-17 Helmut Dr. Innsbruck Schmidhammer 14-alkoxy-n-methylmorphinan-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5223507A (en) * 1992-01-21 1993-06-29 G. D. Searle & Co. Method of using opioid compounds as delta opioid selective agonist analgesics
US5354863A (en) * 1992-01-21 1994-10-11 G. D. Searle & Co. Opioid agonist compounds
SE9401728D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds II

Also Published As

Publication number Publication date
JP2001504829A (ja) 2001-04-10
AU1402497A (en) 1998-06-10
EP0946564A1 (fr) 1999-10-06
WO1998022467A1 (fr) 1998-05-28

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Legal Events

Date Code Title Description
FZDE Dead