CA2268382A1 - Overproduction of riboflavin in yeast - Google Patents

Overproduction of riboflavin in yeast Download PDF

Info

Publication number
CA2268382A1
CA2268382A1 CA002268382A CA2268382A CA2268382A1 CA 2268382 A1 CA2268382 A1 CA 2268382A1 CA 002268382 A CA002268382 A CA 002268382A CA 2268382 A CA2268382 A CA 2268382A CA 2268382 A1 CA2268382 A1 CA 2268382A1
Authority
CA
Canada
Prior art keywords
leu
glu
riboflavin
arg
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002268382A
Other languages
English (en)
French (fr)
Inventor
Lyubov Ya. Babyak
Adelbert Bacher
Yuriy R. Boretskyy
Vasyl V. Demchyshyn
Sabine Eberhardt
Dariya Fedorovych
Holger Luttgen
Gerald Richter
Adolphus Van Loon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2268382A1 publication Critical patent/CA2268382A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Animal Husbandry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA002268382A 1998-04-23 1999-04-21 Overproduction of riboflavin in yeast Abandoned CA2268382A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98107380 1998-04-23
EP98107380.2 1998-04-23

Publications (1)

Publication Number Publication Date
CA2268382A1 true CA2268382A1 (en) 1999-10-23

Family

ID=8231806

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002268382A Abandoned CA2268382A1 (en) 1998-04-23 1999-04-21 Overproduction of riboflavin in yeast

Country Status (9)

Country Link
US (1) US6376222B1 (https=)
JP (1) JP2000050883A (https=)
KR (1) KR100671593B1 (https=)
CN (1) CN1166770C (https=)
AU (1) AU2398499A (https=)
BR (1) BR9901399A (https=)
CA (1) CA2268382A1 (https=)
ID (1) ID23301A (https=)
NO (1) NO991924L (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
EP1537233B1 (en) * 2002-09-06 2007-06-06 Basf Aktiengesellschaft Gtp cyclohydrolase ii as a target for fungicides
WO2007058407A1 (en) 2005-11-16 2007-05-24 Korea Research Institute Of Bioscience & Biotechnology Translational elongation factor promoter from pichia pastoris and method for producing recombinant protein using the same
CN114502718A (zh) * 2019-10-04 2022-05-13 科纳根公司 α-紫罗酮和β-紫罗酮的生物合成
CN113801910A (zh) * 2021-08-30 2021-12-17 湖北广济药业股份有限公司 一种纯天然核黄素的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821090A (en) 1994-03-25 1998-10-13 Basf Aktiengesellschaft Riboflavin-biosynthesis in fungi

Also Published As

Publication number Publication date
ID23301A (id) 2000-04-05
KR100671593B1 (ko) 2007-01-18
KR19990083401A (ko) 1999-11-25
US6376222B1 (en) 2002-04-23
NO991924L (no) 1999-10-25
CN1166770C (zh) 2004-09-15
NO991924D0 (no) 1999-04-22
JP2000050883A (ja) 2000-02-22
CN1232872A (zh) 1999-10-27
AU2398499A (en) 1999-11-04
BR9901399A (pt) 2000-03-28

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Legal Events

Date Code Title Description
FZDE Discontinued