CA2266418A1 - Proteases et leurs variants, sur lesquels sont fondus des inhibiteurs de protease peptidique - Google Patents

Proteases et leurs variants, sur lesquels sont fondus des inhibiteurs de protease peptidique Download PDF

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Publication number
CA2266418A1
CA2266418A1 CA002266418A CA2266418A CA2266418A1 CA 2266418 A1 CA2266418 A1 CA 2266418A1 CA 002266418 A CA002266418 A CA 002266418A CA 2266418 A CA2266418 A CA 2266418A CA 2266418 A1 CA2266418 A1 CA 2266418A1
Authority
CA
Canada
Prior art keywords
protease
fusion protein
inhibitor
alkyl
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002266418A
Other languages
English (en)
Inventor
Charles Winston Saunders
John Mcmillan Mciver
James Michael Armpriester
Robert Scott Youngquist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2266418A1 publication Critical patent/CA2266418A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention se rapporte à des protéines de fusion et à leurs utilisations, ainsi qu'aux gènes codant lesdites protéines de fusion. L'invention se rapporte également à des compositions de nettoyage contenant lesdites protéines de fusion.
CA002266418A 1996-09-24 1997-09-23 Proteases et leurs variants, sur lesquels sont fondus des inhibiteurs de protease peptidique Abandoned CA2266418A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2694796P 1996-09-24 1996-09-24
US60/026,947 1996-09-24
PCT/US1997/016354 WO1998013483A1 (fr) 1996-09-24 1997-09-23 Proteases et leurs variants, sur lesquels sont fondus des inhibiteurs de protease peptidique

Publications (1)

Publication Number Publication Date
CA2266418A1 true CA2266418A1 (fr) 1998-04-02

Family

ID=21834730

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002266418A Abandoned CA2266418A1 (fr) 1996-09-24 1997-09-23 Proteases et leurs variants, sur lesquels sont fondus des inhibiteurs de protease peptidique

Country Status (7)

Country Link
EP (1) EP0941312A1 (fr)
JP (1) JP2000506393A (fr)
CN (1) CN1238805A (fr)
AR (1) AR009818A1 (fr)
BR (1) BR9712838A (fr)
CA (1) CA2266418A1 (fr)
WO (1) WO1998013483A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9911891A (pt) * 1998-07-07 2001-03-27 Procter & Gamble Proteases fundidas com variantes de inibidor de subtilisina de streptomyces
EP1313862A1 (fr) * 2000-08-21 2003-05-28 Novozymes A/S Procede de production d'un complexe inhibiteur de proteases
US6783941B2 (en) 2000-12-06 2004-08-31 Novozymes A/S Method for producing a polynucleotide library in vitro by mismatch repair of heteroduplexes
WO2003041680A1 (fr) * 2001-11-13 2003-05-22 The Procter & Gamble Company Compositions topiques contenant des enzymes stabilisees a l'aide d'inhibiteurs
WO2011036153A1 (fr) * 2009-09-25 2011-03-31 Novozymes A/S Composition détergente
JP2012180514A (ja) * 2011-02-10 2012-09-20 Sanyo Chem Ind Ltd 液体洗剤組成物
JP6214382B2 (ja) * 2013-12-19 2017-10-18 花王株式会社 衣料用洗浄剤組成物
CN113166231A (zh) 2018-10-10 2021-07-23 诺维信公司 胰凝乳蛋白酶抑制剂变体及其用途
EP3875591A4 (fr) * 2018-10-31 2022-09-21 Qingdao Vland Biotech Group Co. Ltd. Procédé de production d'une enzyme pour détergent ayant une résistance aux protéases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340740C (fr) * 1987-12-08 1999-09-14 Eileen R. Mulvihill Coexpressiondans des cellules eucaryotes
US5371198A (en) * 1991-12-16 1994-12-06 Novo Nordisk A/S Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
DK43192D0 (da) * 1992-03-31 1992-03-31 Novo Nordisk As Detergentkomposition

Also Published As

Publication number Publication date
WO1998013483A1 (fr) 1998-04-02
BR9712838A (pt) 2000-12-05
AR009818A1 (es) 2000-05-03
CN1238805A (zh) 1999-12-15
JP2000506393A (ja) 2000-05-30
EP0941312A1 (fr) 1999-09-15

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued