CA2266347C - Catheter d'electroporation et d'iontophorese comportant un ballonnet poreux - Google Patents

Catheter d'electroporation et d'iontophorese comportant un ballonnet poreux Download PDF

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Publication number
CA2266347C
CA2266347C CA002266347A CA2266347A CA2266347C CA 2266347 C CA2266347 C CA 2266347C CA 002266347 A CA002266347 A CA 002266347A CA 2266347 A CA2266347 A CA 2266347A CA 2266347 C CA2266347 C CA 2266347C
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CA
Canada
Prior art keywords
electrode
bladder
catheter
outer perforated
distal end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002266347A
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English (en)
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CA2266347A1 (fr
Inventor
Gunter A. Hofmann
Lois J. Crandell
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Genetronics Inc
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Genetronics Inc
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Publication date
Application filed by Genetronics Inc filed Critical Genetronics Inc
Publication of CA2266347A1 publication Critical patent/CA2266347A1/fr
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Publication of CA2266347C publication Critical patent/CA2266347C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body

Abstract

Cette invention concerne un appareil d'électroporation, lequel permet d'introduire des molécules dans des cellules en un endroit prédéterminé dans la cavité du corps d'un patient. Cet appareil comprend un cathéter allongé (10) qui possède une extrémité proximale (16) et une extrémité distale (14), ainsi qu'un câble de guidage qui s'étend de l'extrémité proximale à l'extrémité distale. L'extrémité distale supporte un ballonnet gonflable (14), lequel comprend une vessie interne gonflable ainsi qu'une vessie externe perforée qui définissent une chambre entre elles. Cet appareil comprend également une première électrode (26) située sur la surface externe de la vessie externe perforée, une deuxième électrode (24) espacée de la première, une électrode située à distance (25), ainsi qu'un jour. Ce dernier permet d'administrer une quantité prédéterminée d'un milieu fluide porteur des molécules choisies, dans la chambre qui doit être infusée en un endroit prédéterminé dans la cavité du corps. Cet appareil comprend en outre une source d'alimentation électrique (47) qui permet d'appliquer une impulsion de tension entre des paires d'électrodes choisies. Cette impulsion va assurer le transport par iontophorèse des molécules et/ou générer de manière répétitive des champs électriques d'une amplitude et d'une durée prédéterminées. Ces derniers vont rendre les parois de plusieurs cellules temporairement perméables à l'endroit prédéterminé, ceci de manière à ce que les molécules puissent pénétrer dans lesdites cellules.
CA002266347A 1996-10-10 1997-03-11 Catheter d'electroporation et d'iontophorese comportant un ballonnet poreux Expired - Fee Related CA2266347C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/729,007 1996-10-10
US08/729,007 US5704908A (en) 1996-10-10 1996-10-10 Electroporation and iontophoresis catheter with porous balloon
PCT/US1997/003760 WO1998015318A1 (fr) 1996-10-10 1997-03-11 Catheter d'electroporation et d'iontophorese comportant un ballonnet poreux

Publications (2)

Publication Number Publication Date
CA2266347A1 CA2266347A1 (fr) 1998-04-16
CA2266347C true CA2266347C (fr) 2005-12-20

Family

ID=24929196

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002266347A Expired - Fee Related CA2266347C (fr) 1996-10-10 1997-03-11 Catheter d'electroporation et d'iontophorese comportant un ballonnet poreux

Country Status (5)

Country Link
US (1) US5704908A (fr)
EP (1) EP1011791A1 (fr)
JP (1) JP3522287B2 (fr)
CA (1) CA2266347C (fr)
WO (1) WO1998015318A1 (fr)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6041252A (en) * 1995-06-07 2000-03-21 Ichor Medical Systems Inc. Drug delivery system and method
US6743197B1 (en) * 1996-07-10 2004-06-01 Novasys Medical, Inc. Treatment of discrete tissues in respiratory, urinary, circulatory, reproductive and digestive systems
JP4105238B2 (ja) * 1997-04-01 2008-06-25 ムンターマン，アクセル カテーテルと組織の接触を検知するとともにカテーテル切除の際に組織との相互作用を検知するためのシステム
US5873849A (en) * 1997-04-24 1999-02-23 Ichor Medical Systems, Inc. Electrodes and electrode arrays for generating electroporation inducing electrical fields
US6061587A (en) * 1997-05-15 2000-05-09 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US9023031B2 (en) * 1997-08-13 2015-05-05 Verathon Inc. Noninvasive devices, methods, and systems for modifying tissues
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
US20100114087A1 (en) * 1998-02-19 2010-05-06 Edwards Stuart D Methods and devices for treating urinary incontinence
US6219577B1 (en) 1998-04-14 2001-04-17 Global Vascular Concepts, Inc. Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
WO1999058188A1 (fr) 1998-05-08 1999-11-18 Genetronics, Inc. Vasodilatation d'un vaisseau induite electriquement
US6267747B1 (en) 1998-05-11 2001-07-31 Cardeon Corporation Aortic catheter with porous aortic root balloon and methods for inducing cardioplegic arrest
US6206283B1 (en) * 1998-12-23 2001-03-27 At&T Corp. Method and apparatus for transferring money via a telephone call
US8177743B2 (en) 1998-05-18 2012-05-15 Boston Scientific Scimed, Inc. Localized delivery of drug agents
US6280411B1 (en) * 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
AU5333599A (en) * 1998-08-06 2000-02-28 Cardeon Corporation Aortic catheter with porous aortic arch balloon and methods for selective aorticperfusion
US6192270B1 (en) * 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue
US6425877B1 (en) * 1999-04-02 2002-07-30 Novasys Medical, Inc. Treatment of tissue in the digestive circulatory respiratory urinary and reproductive systems
US6587718B2 (en) * 1999-10-08 2003-07-01 Scimed Life Systems, Inc. Iontophoretic delivery to heart tissue
US6733513B2 (en) 1999-11-04 2004-05-11 Advanced Bioprosthetic Surfaces, Ltd. Balloon catheter having metal balloon and method of making same
US6575932B1 (en) 1999-12-02 2003-06-10 Ottawa Heart Institute Adjustable multi-balloon local delivery device
CA2395492A1 (fr) * 1999-12-22 2001-07-05 Diana Wang Procede et appareil permettant de cibler une electroporation localisee
US7079882B1 (en) 2000-01-22 2006-07-18 Richard Schmidt Method and apparatus for quantifying nerve and neural-muscular integrity related to pelvic organs or pelvic floor functions
EP1309904A4 (fr) * 2000-03-03 2006-03-29 Valentis Inc Compositions ameliorees de poloxamere et de poloxamine generatrices d'acide nucleique
ATE511400T1 (de) * 2000-03-03 2011-06-15 Genetronics Inc Nukleinsäure-fomulierungen zur genverabreichung
AU2001249308A1 (en) * 2000-03-24 2001-10-15 Johns Hopkins University Peritoneal cavity device and method
AU2001264759B2 (en) 2000-05-22 2006-06-01 Merck & Co., Inc. System and method for assessing the performance of a pharmaceutical agent delivery system
AU2001296354A1 (en) 2000-09-25 2002-04-02 Baylor College Of Medicine Improved system for regulation of transgene expression
US7306591B2 (en) 2000-10-02 2007-12-11 Novasys Medical, Inc. Apparatus and methods for treating female urinary incontinence
US20040009940A1 (en) * 2000-10-20 2004-01-15 Coleman Michael E. Gene delivery formulations and methods for treatment of ischemic conditions
US6934589B2 (en) * 2000-12-29 2005-08-23 Medtronic, Inc. System and method for placing endocardial leads
US7776029B2 (en) * 2001-01-30 2010-08-17 The Alfred E. Mann Foundation For Scientific Research Microminiature infusion pump
US7018371B2 (en) * 2001-05-07 2006-03-28 Xoft, Inc. Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia
US6537195B2 (en) * 2001-05-07 2003-03-25 Xoft, Microtube, Inc. Combination x-ray radiation and drug delivery devices and methods for inhibiting hyperplasia
AU2002324909A1 (en) * 2001-09-07 2003-03-24 Baylor College Of Medicine Linear dna fragments for gene expression
WO2003038112A2 (fr) 2001-10-26 2003-05-08 Baylor College Of Medicine Composition et methode permettant de modifier la masse maigre et les proprietes osseuses d'un sujet
US7488313B2 (en) * 2001-11-29 2009-02-10 Boston Scientific Scimed, Inc. Mechanical apparatus and method for dilating and delivering a therapeutic agent to a site of treatment
US7241744B2 (en) * 2001-12-11 2007-07-10 Baylor College Of Medicine Treating anemia in subjects by administration of plasmids encoding growth hormone releasing hormone
US6740081B2 (en) * 2002-01-25 2004-05-25 Applied Medical Resources Corporation Electrosurgery with improved control apparatus and method
AU2003230601A1 (en) 2002-03-07 2003-09-22 Instituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Clinical syringe with electrical stimulation aspects
US7245963B2 (en) * 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
US8209006B2 (en) * 2002-03-07 2012-06-26 Vgx Pharmaceuticals, Inc. Constant current electroporation device and methods of use
US20110207758A1 (en) * 2003-04-08 2011-08-25 Medtronic Vascular, Inc. Methods for Therapeutic Renal Denervation
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US8175711B2 (en) 2002-04-08 2012-05-08 Ardian, Inc. Methods for treating a condition or disease associated with cardio-renal function
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US6978174B2 (en) * 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7620451B2 (en) * 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US20040014645A1 (en) * 2002-05-28 2004-01-22 Advisys, Inc. Increased delivery of a nucleic acid construct in vivo by the poly-L-glutamate ("PLG") system
US20040034336A1 (en) * 2002-08-08 2004-02-19 Neal Scott Charged liposomes/micelles with encapsulted medical compounds
EP1603945A2 (fr) 2003-03-12 2005-12-14 Advisys, Inc. Suplementation d'igf-i avec mediation par plasmide pour applications therapeutiques
TW200424214A (en) * 2003-04-21 2004-11-16 Advisys Inc Plasmid mediated GHRH supplementation for renal failures
US7517342B2 (en) * 2003-04-29 2009-04-14 Boston Scientific Scimed, Inc. Polymer coated device for electrically medicated drug delivery
WO2005016964A2 (fr) * 2003-08-04 2005-02-24 Advisys, Inc. Hormone liberant une hormone de croissance specifique du chien
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
JP4899020B2 (ja) * 2004-03-25 2012-03-21 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク 組織の予防的処置又は治療に用いるための装置
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US8105324B2 (en) * 2004-09-24 2012-01-31 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for the non-thermal, electrically-induced closure of blood vessels
US20070083239A1 (en) * 2005-09-23 2007-04-12 Denise Demarais Methods and apparatus for inducing, monitoring and controlling renal neuromodulation
US7937143B2 (en) * 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
WO2006063199A2 (fr) 2004-12-09 2006-06-15 The Foundry, Inc. Reparation de valvule sigmoide aortique
US7678075B2 (en) * 2004-12-30 2010-03-16 Advanced Cardiovascular Systems, Inc. Infusion catheter and use thereof
US7850645B2 (en) * 2005-02-11 2010-12-14 Boston Scientific Scimed, Inc. Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
US20080076729A1 (en) * 2005-05-19 2008-03-27 Schering Aktiengesellachaft Interferon-beta gene therapy using an improved, regulated expression system
US20070179113A1 (en) * 2005-05-19 2007-08-02 Schering Aktiengesellachaft GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
AR053285A1 (es) * 2005-05-19 2007-04-25 Schering Ag Tratamiento de enfemedades usando un sistema mejorado de expresion regulada
EP1891224A1 (fr) * 2005-05-19 2008-02-27 Bayer Schering Pharma Aktiengesellschaft Therapie genique a base d'interferons beta utilisant un systeme d'expression regulee, ameliore
KR100660121B1 (ko) 2005-07-18 2006-12-20 (주)태연메디칼 척추복원시술용 복원기
US8888684B2 (en) * 2006-03-27 2014-11-18 Boston Scientific Scimed, Inc. Medical devices with local drug delivery capabilities
AU2007247110A1 (en) 2006-05-09 2007-11-15 Syntach Ag Formation of therapeutic scar using small particles
NZ574597A (en) * 2006-07-03 2011-11-25 Hemoteq Ag Stent coated with a biodegradable polymer and rapamycin
NZ588816A (en) * 2007-01-21 2011-11-25 Hemoteq Ag Medical device for the treatment of stenoses of corporal lumina and for the prevention of impending restenoses
US9192697B2 (en) * 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
EP2594311A3 (fr) * 2008-03-06 2013-07-10 Boston Scientific Scimed, Inc. Dispositifs de cathéter à ballonnet avec protection gainée
US8849395B2 (en) * 2008-05-30 2014-09-30 Boston Scientific Scimed, Inc. Guide catheter having vasomodulating electrodes
US8386010B2 (en) * 2008-10-23 2013-02-26 Covidien Lp Surgical tissue monitoring system
US20100125238A1 (en) * 2008-11-14 2010-05-20 Therawire, Inc. Iontophoretic Therapeutic Agent Delivery System
US8923970B2 (en) 2008-12-09 2014-12-30 Nephera Ltd. Stimulation of the urinary system
US8725249B2 (en) 2008-12-09 2014-05-13 Nephera Ltd. Stimulation of the urinary system
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
PL2401027T3 (pl) * 2009-02-26 2018-04-30 The University Of North Carolina At Chapel Hill Układ do interwencyjnego dostarczania leku
EP2421571A2 (fr) * 2009-04-24 2012-02-29 Boston Scientific Scimed, Inc. Utilisation de formes polymorphes de médicament pour permettre une libération contrôlée de médicament à partir d'un dispositif médical à revêtement
US20120078163A1 (en) 2009-05-27 2012-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of generating connective tissue
WO2011005421A2 (fr) * 2009-07-10 2011-01-13 Boston Scientific Scimed, Inc. Utilisation de nanocristaux pour un ballonnet de distribution de médicament
JP5933434B2 (ja) 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 薬剤送達バルーンの製造方法
US20110054396A1 (en) * 2009-08-27 2011-03-03 Boston Scientific Scimed, Inc. Balloon Catheter Devices With Drug-Coated Sheath
US8889211B2 (en) 2010-09-02 2014-11-18 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
CN103313671B (zh) 2010-10-25 2017-06-06 美敦力Af卢森堡有限责任公司 用于神经调节治疗的估算及反馈的装置、系统及方法
RU2466755C2 (ru) * 2010-12-10 2012-11-20 Владимир Владимирович Протощак Способ проведения внутриорганного лекарственного электрофореза мочевого пузыря
US10238776B2 (en) * 2010-12-29 2019-03-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Hydrophobic catheter and composition
CN103517731B (zh) 2011-04-08 2016-08-31 柯惠有限合伙公司 用于去除肾交感神经和离子电渗式药物传递的离子电渗式药物传递系统和方法
CN103930061B (zh) 2011-04-25 2016-09-14 美敦力阿迪安卢森堡有限责任公司 用于限制导管壁低温消融的有关低温球囊限制部署的装置及方法
ITTO20110411A1 (it) * 2011-05-11 2012-11-12 Consiglio Nazionale Ricerche Dispositivo per elettroporazione
WO2012158132A1 (fr) 2011-05-18 2012-11-22 Eteka Llc Appareil de stimulation des propriétés nutritionnelles par électroporation ou champs électriques pulsés
WO2013022458A1 (fr) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Procédés de conversion d'une substance médicamenteuse amorphe en une forme cristalline
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
BR112014019431A8 (pt) 2012-02-07 2017-07-11 Global Bio Therapeutics Usa Inc Método compartimentalizado de distribuição de ácido nucleico e composições e usos desses
ITCO20120004A1 (it) * 2012-02-07 2013-08-08 Giuseppe Caccia Apparecchio per elettroporazzione dinamica vaginale e anale
AU2013229776B2 (en) 2012-03-08 2016-12-15 Medtronic Af Luxembourg S.A.R.L. Biomarker sampling in the context of neuromodulation devices and associated systems
WO2013134548A2 (fr) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation ovarienne, systèmes et procédés associés
US9801681B2 (en) * 2012-08-17 2017-10-31 Medtronic Ablation Frontiers Llc Catheters and methods for intracardiac electrical mapping
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
US9913933B2 (en) 2013-03-15 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Multilayered catheter shaft containing polyvinylidene fluoride polymers
US10568686B2 (en) * 2013-11-21 2020-02-25 Biosense Webster (Israel) Ltd. Multi-electrode balloon catheter with circumferential and point electrodes
US9579149B2 (en) 2014-03-13 2017-02-28 Medtronic Ardian Luxembourg S.A.R.L. Low profile catheter assemblies and associated systems and methods
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10918840B2 (en) 2014-05-06 2021-02-16 Hydra Vascular Llc Drug device electroporation system
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
US10376308B2 (en) 2015-02-05 2019-08-13 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
WO2017062753A1 (fr) 2015-10-07 2017-04-13 Mayo Foundation For Medical Education And Research Électroporation pour le traitement de l'obésité ou le diabète
DK3474760T3 (da) 2016-06-27 2023-03-20 Galvanize Therapeutics Inc Generator og et kateter med en elektrode til at behandle en lungepassage
US10233419B2 (en) 2016-06-30 2019-03-19 Zymergen Inc. Apparatuses and methods for electroporation
US11154354B2 (en) 2016-07-29 2021-10-26 Axon Therapies, Inc. Devices, systems, and methods for treatment of heart failure by splanchnic nerve ablation
US10561461B2 (en) 2017-12-17 2020-02-18 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
AU2019210741A1 (en) 2018-01-26 2020-08-06 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
AU2019263465A1 (en) * 2018-05-02 2020-12-24 Oncosec Medical Incorporated Electroporation systems, methods, and apparatus
EP3952972A4 (fr) 2019-04-08 2023-06-21 Udayan Patel Ballonnet gonflable sur cathéter avec passage de dérivation
US11660139B2 (en) 2019-04-10 2023-05-30 Radioclash Inc. Electroporation probe
EP4241836A3 (fr) 2019-06-20 2023-11-29 Axon Therapies, Inc. Dispositifs d'ablation endovasculaire d'un nerf splanchnique
CN114945341A (zh) 2020-01-17 2022-08-26 阿克松疗法公司 用于内脏神经的血管内消融的方法和装置
US20210369338A1 (en) * 2020-06-01 2021-12-02 Biosense Webster (Israel) Ltd. Application of irreversible electroporation (ire) ablation using catheter with electrode array

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1069826A1 (ru) * 1982-09-17 1984-01-30 Запорожский медицинский институт Эндотрахеальна трубка
SU1146057A1 (ru) * 1982-09-17 1985-03-23 Запорожский медицинский институт Эндотрахеальна трубка
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
US5498238A (en) * 1990-06-15 1996-03-12 Cortrak Medical, Inc. Simultaneous angioplasty and phoretic drug delivery
DE69110467T2 (de) * 1990-06-15 1996-02-01 Cortrak Medical Inc Vorrichtung zur abgabe von medikamenten.
US5304120A (en) * 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
US5507724A (en) * 1992-07-01 1996-04-16 Genetronics, Inc. Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
US5505700A (en) * 1994-06-14 1996-04-09 Cordis Corporation Electro-osmotic infusion catheter

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CA2266347A1 (fr) 1998-04-16
WO1998015318A1 (fr) 1998-04-16
EP1011791A1 (fr) 2000-06-28
US5704908A (en) 1998-01-06
JP2000508220A (ja) 2000-07-04
JP3522287B2 (ja) 2004-04-26

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