CA2263586A1 - Nouveaux aryle-pyridazines - Google Patents
Nouveaux aryle-pyridazines Download PDFInfo
- Publication number
- CA2263586A1 CA2263586A1 CA002263586A CA2263586A CA2263586A1 CA 2263586 A1 CA2263586 A1 CA 2263586A1 CA 002263586 A CA002263586 A CA 002263586A CA 2263586 A CA2263586 A CA 2263586A CA 2263586 A1 CA2263586 A1 CA 2263586A1
- Authority
- CA
- Canada
- Prior art keywords
- chlorophenyl
- tetrahydro
- pyrazole
- benzopyrano
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/36—Benzo-cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
L'invention concerne un composé selon la formle (I). Dans cette dernière, A, A?1¿, A?2¿ et A?3¿ sont tous CH ou CR?4¿ ou un élément parmi A, A?1¿, A?2¿ ou A?3¿ est de l'azone et les autres sont tous CH ou CR?4¿. Ar?1¿ et Ar?2¿ représentent, indépendamment, phényle, pyridyle, benzothiazolyle, quinolyle ou quinoxalinyle, tous éventuellement substitués par un ou plusieurs substituents. X, Y, Z, R?1¿, R?2¿, R?3¿, R?4¿ sont tels que définis dans le descriptif, ou un dérivé pharmaceutiquement acceptable de ce dernier dans la fabrication d'un médicament pour le traitement des allergies ou des inflammations.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9618487.4A GB9618487D0 (en) | 1996-09-05 | 1996-09-05 | Pharmaceutically active compounds |
GBGB9619122.6A GB9619122D0 (en) | 1996-09-12 | 1996-09-12 | Pharmaceutically active compounds |
GBGB9619642.3A GB9619642D0 (en) | 1996-09-20 | 1996-09-20 | Compounds |
GB9619642.3 | 1996-09-20 | ||
GB9619122.6 | 1996-09-20 | ||
GB9618487.4 | 1996-09-20 | ||
PCT/SE1997/001359 WO1998009969A1 (fr) | 1996-09-05 | 1997-08-19 | Nouveaux aryle-pyridazines |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2263586A1 true CA2263586A1 (fr) | 1998-03-12 |
Family
ID=27268459
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002263586A Abandoned CA2263586A1 (fr) | 1996-09-05 | 1997-08-19 | Nouveaux aryle-pyridazines |
Country Status (6)
Country | Link |
---|---|
JP (1) | JP2001501180A (fr) |
AR (1) | AR009322A1 (fr) |
AU (1) | AU711539B2 (fr) |
CA (1) | CA2263586A1 (fr) |
ID (1) | ID17393A (fr) |
WO (1) | WO1998009969A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2667966C (fr) * | 2006-10-31 | 2011-08-02 | Pfizer Products Inc. | Composes de pyrazoline en tant qu'antagonistes des recepteurs mineralocorticoides |
US7999107B2 (en) | 2007-01-31 | 2011-08-16 | Merck Sharp & Dohme Corp. | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators |
CN102372710A (zh) * | 2010-08-18 | 2012-03-14 | 山东轩竹医药科技有限公司 | 作为盐皮质激素受体拮抗剂的并环类化合物 |
MX360889B (es) * | 2012-12-22 | 2018-11-20 | Kbp Biosciences Co Ltd | Forma cristalina de un compuesto usado como un antagonista del receptor mineralocorticoide y metodo de preparacion de la misma. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE92476T1 (de) * | 1987-11-02 | 1993-08-15 | Yoshitomi Pharmaceutical | Kondensierte pyridazin-verbindungen und deren verwendung als arzneimittel. |
GB8818895D0 (en) * | 1988-08-09 | 1988-09-14 | Boots Co Plc | Therapeutic agents |
HU9202510D0 (en) * | 1990-02-02 | 1992-10-28 | Boots Co Plc | Method for producing new 1-benzo-pyrano(4,3)pyrazole derivatives and those of 1-benzo-thiopyrano(4,3)pyrazole and pharmaceutical preparatives containing said compounds |
-
1997
- 1997-08-19 WO PCT/SE1997/001359 patent/WO1998009969A1/fr not_active Application Discontinuation
- 1997-08-19 JP JP10512539A patent/JP2001501180A/ja active Pending
- 1997-08-19 CA CA002263586A patent/CA2263586A1/fr not_active Abandoned
- 1997-08-19 AU AU38736/97A patent/AU711539B2/en not_active Ceased
- 1997-08-25 AR ARP970103852A patent/AR009322A1/es unknown
- 1997-09-04 ID IDP973081A patent/ID17393A/id unknown
Also Published As
Publication number | Publication date |
---|---|
WO1998009969A1 (fr) | 1998-03-12 |
AU3873697A (en) | 1998-03-26 |
ID17393A (id) | 1997-12-24 |
AU711539B2 (en) | 1999-10-14 |
JP2001501180A (ja) | 2001-01-30 |
AR009322A1 (es) | 2000-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |