CA2256694A1 - Synthese combinatoire de banques d'hydrates de carbone - Google Patents

Synthese combinatoire de banques d'hydrates de carbone Download PDF

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Publication number
CA2256694A1
CA2256694A1 CA002256694A CA2256694A CA2256694A1 CA 2256694 A1 CA2256694 A1 CA 2256694A1 CA 002256694 A CA002256694 A CA 002256694A CA 2256694 A CA2256694 A CA 2256694A CA 2256694 A1 CA2256694 A1 CA 2256694A1
Authority
CA
Canada
Prior art keywords
group
thiosaccharide
compound
thio
supports
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002256694A
Other languages
English (en)
Inventor
Ole Hindsgaul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synsorb Biotech Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/751,231 external-priority patent/US5780603A/en
Priority claimed from US08/751,510 external-priority patent/US6063769A/en
Application filed by Individual filed Critical Individual
Publication of CA2256694A1 publication Critical patent/CA2256694A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
    • C07H5/10—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00731—Saccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/12—Libraries containing saccharides or polysaccharides, or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne des procédés de synthèse de collections très importantes de divers dérivés thiosaccharides, éventuellement fixés sur un support solide, et elle concerne également des banques de divers dérivés thiosaccharides.
CA002256694A 1996-11-15 1997-11-14 Synthese combinatoire de banques d'hydrates de carbone Abandoned CA2256694A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/751,231 1996-11-15
US08/751,231 US5780603A (en) 1996-11-15 1996-11-15 Combinatorial synthesis of carbohydrate libraries
US08/751,510 US6063769A (en) 1996-11-14 1996-11-15 1-thiogalactose derivatives
US08/751,510 1996-11-15
PCT/CA1997/000866 WO1998022487A1 (fr) 1996-11-15 1997-11-14 Synthese combinatoire de banques d'hydrates de carbone

Publications (1)

Publication Number Publication Date
CA2256694A1 true CA2256694A1 (fr) 1998-05-28

Family

ID=27115386

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002256694A Abandoned CA2256694A1 (fr) 1996-11-15 1997-11-14 Synthese combinatoire de banques d'hydrates de carbone

Country Status (6)

Country Link
EP (1) EP0938492A1 (fr)
JP (1) JP2001505558A (fr)
AU (1) AU736031B2 (fr)
CA (1) CA2256694A1 (fr)
NZ (1) NZ332975A (fr)
WO (1) WO1998022487A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1175427B1 (fr) 1999-03-05 2010-08-18 Massachusetts Institute Of Technology Lieurs utilises dans la synthese d'oligosaccharides sur supports solides
WO2001027327A2 (fr) 1999-10-08 2001-04-19 Protogene Laboratories, Inc. Procede et appareil destines a produire un grand nombre de reactions au moyen d'une plaque matrice
JP2006151948A (ja) * 2004-11-04 2006-06-15 Institute Of Physical & Chemical Research 糖鎖合成方法および糖鎖自動合成装置
EP2402346A1 (fr) 2005-11-22 2012-01-04 Controlled Chemicals, Inc. Procédés pour la réduction des taux d'accepteurs de Michael contaminants dans l'oxycodone et d'autres compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0532689A (ja) * 1991-08-01 1993-02-09 Nippon Fine Chem Co Ltd 膜タンパク質の可溶化剤
ATE148889T1 (de) * 1991-09-18 1997-02-15 Affymax Tech Nv Verfahren zur synthese der verschiedenen sammlungen von oligomeren
JPH08511234A (ja) * 1993-02-23 1996-11-26 ザ トラスティーズ オブ プリンストン ユニヴァーシティー グリコシド結合の溶液及び固相形成
US5571902A (en) * 1993-07-29 1996-11-05 Isis Pharmaceuticals, Inc. Synthesis of oligonucleotides
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
US5484773A (en) * 1994-02-14 1996-01-16 Alberta Research Council Treatment of antibiotic associated diarrhea

Also Published As

Publication number Publication date
WO1998022487A1 (fr) 1998-05-28
NZ332975A (en) 2001-06-29
JP2001505558A (ja) 2001-04-24
AU736031B2 (en) 2001-07-26
AU5044098A (en) 1998-06-10
EP0938492A1 (fr) 1999-09-01

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