CA2252038C - Pulverisateur ou capsule polaire d'aerosols buccaux - Google Patents

Pulverisateur ou capsule polaire d'aerosols buccaux Download PDF

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Publication number
CA2252038C
CA2252038C CA002252038A CA2252038A CA2252038C CA 2252038 C CA2252038 C CA 2252038C CA 002252038 A CA002252038 A CA 002252038A CA 2252038 A CA2252038 A CA 2252038A CA 2252038 C CA2252038 C CA 2252038C
Authority
CA
Canada
Prior art keywords
active compound
polar solvent
spray
flavoring agent
pharmacologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002252038A
Other languages
English (en)
Other versions
CA2252038A1 (fr
Inventor
Harry A. Dugger, Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SUDA Ltd
Original Assignee
Flemington Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flemington Pharmaceutical Corp filed Critical Flemington Pharmaceutical Corp
Priority claimed from PCT/US1997/002793 external-priority patent/WO1997038662A2/fr
Publication of CA2252038A1 publication Critical patent/CA2252038A1/fr
Application granted granted Critical
Publication of CA2252038C publication Critical patent/CA2252038C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un pulvérisateur ou une capsule d'aérosols buccaux utilisant un solvant polaire. Ce pulvérisateur ou cette capsule fournissent des composés biologiquement actifs en vue de leur absorption rapide par les muqueuses buccales, ce qui permet d'obtenir un effet très rapidement. Le pulvérisateur d'aérosol buccal selon l'invention comprend 5-50 % de solvant polaire, 0,0025-40 % d'un composé actif, 0,05-5 % d'un agent aromatisant. La capsule de gélatine molle selon l'invention comprend comme composition de remplissage: 75-99 % d'un solvant polaire, 0-20 % d'émulsifiant, 0,0003-35 % de composé actif, et 0,05-60 % d'un agent aromatisant.
CA002252038A 1996-04-12 1997-02-21 Pulverisateur ou capsule polaire d'aerosols buccaux Expired - Fee Related CA2252038C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63006596A 1996-04-12 1996-04-12
US08/630,065 1996-04-12
PCT/US1997/002793 WO1997038662A2 (fr) 1996-04-12 1997-02-21 Pulverisateur ou capsule polaire d'aerosols buccaux

Publications (2)

Publication Number Publication Date
CA2252038A1 CA2252038A1 (fr) 1997-10-23
CA2252038C true CA2252038C (fr) 2006-10-10

Family

ID=37114287

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002252038A Expired - Fee Related CA2252038C (fr) 1996-04-12 1997-02-21 Pulverisateur ou capsule polaire d'aerosols buccaux

Country Status (1)

Country Link
CA (1) CA2252038C (fr)

Also Published As

Publication number Publication date
CA2252038A1 (fr) 1997-10-23

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Effective date: 20170221