CA2245713A1 - Processus continus pour l'hydrolyse de cyanopyridines sous conditions sensiblement adiabatiques - Google Patents

Processus continus pour l'hydrolyse de cyanopyridines sous conditions sensiblement adiabatiques Download PDF

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Publication number
CA2245713A1
CA2245713A1 CA 2245713 CA2245713A CA2245713A1 CA 2245713 A1 CA2245713 A1 CA 2245713A1 CA 2245713 CA2245713 CA 2245713 CA 2245713 A CA2245713 A CA 2245713A CA 2245713 A1 CA2245713 A1 CA 2245713A1
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CA
Canada
Prior art keywords
cyanopyridine
base
equivalents
reacting
hydrolysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2245713
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English (en)
Inventor
Robert A. Kattau
George Kreilis
Wei Cao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertellus Specialties Inc
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1997/001657 external-priority patent/WO1997029087A1/fr
Publication of CA2245713A1 publication Critical patent/CA2245713A1/fr
Abandoned legal-status Critical Current

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Abstract

L'invention concerne des processus à préférer pour l'hydrolyse de cyanopyridine substituée et non substituée en présence d'une base, et sous conditions sensiblement adiabatiques, en vue de fabriquer des amides à substitution pyridine et/ou des acides carboxyliques à substitution pyridine. Il est possible de conduire les processus en question dans une variété de réacteurs continus, y compris les séries en cascades de cuves à réaction, réacteurs en boucles ou réacteurs à tube d'écoulement. On préfère en outre utiliser des préparations efficaces et avantageuses de nicotinamide et de niacine, qui représentent des constituants importants du complexe vitaminique B.
CA 2245713 1996-02-09 1997-02-04 Processus continus pour l'hydrolyse de cyanopyridines sous conditions sensiblement adiabatiques Abandoned CA2245713A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1142496P 1996-02-09 1996-02-09
US60/011,424 1996-02-09
PCT/US1997/001657 WO1997029087A1 (fr) 1996-02-09 1997-02-04 Processus continus pour l'hydrolyse de cyanopyridines sous conditions sensiblement adiabatiques

Publications (1)

Publication Number Publication Date
CA2245713A1 true CA2245713A1 (fr) 1997-08-14

Family

ID=29422612

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2245713 Abandoned CA2245713A1 (fr) 1996-02-09 1997-02-04 Processus continus pour l'hydrolyse de cyanopyridines sous conditions sensiblement adiabatiques

Country Status (1)

Country Link
CA (1) CA2245713A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113149903A (zh) * 2021-04-30 2021-07-23 安徽国星生物化学有限公司 一种氰基吡啶的合成方法及装置

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113149903A (zh) * 2021-04-30 2021-07-23 安徽国星生物化学有限公司 一种氰基吡啶的合成方法及装置
CN113149903B (zh) * 2021-04-30 2023-02-10 安徽国星生物化学有限公司 一种氰基吡啶的合成方法及装置

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