CA2233278A1 - Stimulation de reponses immunes cellulaires par une imunisation genique ciblee utilisant un agent particulaire - Google Patents
Stimulation de reponses immunes cellulaires par une imunisation genique ciblee utilisant un agent particulaire Download PDFInfo
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- CA2233278A1 CA2233278A1 CA002233278A CA2233278A CA2233278A1 CA 2233278 A1 CA2233278 A1 CA 2233278A1 CA 002233278 A CA002233278 A CA 002233278A CA 2233278 A CA2233278 A CA 2233278A CA 2233278 A1 CA2233278 A1 CA 2233278A1
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- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
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- Microbiology (AREA)
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- General Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Pregnancy & Childbirth (AREA)
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- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
L'invention concerne différentes méthodes d'immunisation génétique permettant de conférer une immunité à un mammifère hôte vis-à-vis d'un antigène spécifique, en particulier un hôte humain. L'invention se base sur la faculté de diriger des polynucléotides particulaires, capables d'exprimer une protéine ou un fragment de protéine antigénique, sur le cytoplasme des cellules cibles hôtes, telles que les cellules présentant l'antigène. Un apport direct de ces polynucléotides particulaires dans le cytoplasme des cellules présentant l'antigène va stimuler la production de lymphocytes cytotoxiques spécifiques de l'antigène, ce qui va favoriser la destruction de cellules malades, telles que les cellules néoplasiques et les cellules infectées par un virus.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53555695A | 1995-09-28 | 1995-09-28 | |
| US08/535,556 | 1995-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2233278A1 true CA2233278A1 (fr) | 1997-04-03 |
Family
ID=24134735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002233278A Abandoned CA2233278A1 (fr) | 1995-09-28 | 1996-09-27 | Stimulation de reponses immunes cellulaires par une imunisation genique ciblee utilisant un agent particulaire |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0863704A4 (fr) |
| JP (1) | JPH11512724A (fr) |
| KR (1) | KR19990063672A (fr) |
| CN (1) | CN1201369A (fr) |
| AU (1) | AU716497B2 (fr) |
| BG (1) | BG102355A (fr) |
| CA (1) | CA2233278A1 (fr) |
| CZ (1) | CZ92998A3 (fr) |
| HU (1) | HUP9802651A3 (fr) |
| NO (1) | NO981386L (fr) |
| NZ (1) | NZ319891A (fr) |
| PL (1) | PL325953A1 (fr) |
| SK (1) | SK40198A3 (fr) |
| TR (1) | TR199800573T2 (fr) |
| WO (1) | WO1997011605A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3210997A (en) * | 1996-05-24 | 1997-12-09 | University Of Maryland At Baltimore | Dna vaccines for eliciting a mucosal immune response |
| TW570803B (en) * | 1997-04-09 | 2004-01-11 | Duphar Int Res | Influenza vaccine |
| US6287569B1 (en) * | 1997-04-10 | 2001-09-11 | The Regents Of The University Of California | Vaccines with enhanced intracellular processing |
| WO1999041368A2 (fr) * | 1998-02-11 | 1999-08-19 | Maxygen, Inc. | Optimisation des proprietes immunomodulatrices des vaccins genetiques |
| JP2003523721A (ja) | 1998-12-31 | 2003-08-12 | カイロン コーポレイション | 抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用 |
| WO2000063385A2 (fr) * | 1999-04-21 | 2000-10-26 | Powderject Vaccines, Inc. | Immunisation de l'acide nucleique |
| ATE411044T1 (de) * | 2001-03-30 | 2008-10-15 | Ghc Res Dev Corp | Monozyte-spezifisches teilchenförmiges verabreichungsvehikel |
| CA2634992C (fr) | 2001-07-05 | 2012-10-16 | Novartis Vaccines And Diagnostics, Inc. | Polynucleotides codant des polypeptides de type c du vih antigeniques, polypeptides et leurs utilisations |
| US11529414B2 (en) | 2020-06-23 | 2022-12-20 | Orbis Health Solutions, Llc | Viral vaccines for in vivo expression of a nucleic acid encoding an immunogenic peptide and methods of using the same |
-
1996
- 1996-09-27 PL PL96325953A patent/PL325953A1/xx unknown
- 1996-09-27 KR KR1019980702134A patent/KR19990063672A/ko not_active Application Discontinuation
- 1996-09-27 CA CA002233278A patent/CA2233278A1/fr not_active Abandoned
- 1996-09-27 SK SK401-98A patent/SK40198A3/sk unknown
- 1996-09-27 TR TR1998/00573T patent/TR199800573T2/xx unknown
- 1996-09-27 HU HU9802651A patent/HUP9802651A3/hu unknown
- 1996-09-27 EP EP96933987A patent/EP0863704A4/fr not_active Withdrawn
- 1996-09-27 JP JP9513762A patent/JPH11512724A/ja active Pending
- 1996-09-27 CN CN96198106A patent/CN1201369A/zh active Pending
- 1996-09-27 NZ NZ319891A patent/NZ319891A/xx unknown
- 1996-09-27 CZ CZ98929A patent/CZ92998A3/cs unknown
- 1996-09-27 AU AU72515/96A patent/AU716497B2/en not_active Ceased
- 1996-09-27 WO PCT/US1996/015728 patent/WO1997011605A1/fr not_active Application Discontinuation
-
1998
- 1998-03-26 NO NO981386A patent/NO981386L/no unknown
- 1998-03-26 BG BG102355A patent/BG102355A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0863704A1 (fr) | 1998-09-16 |
| HUP9802651A2 (hu) | 1999-02-01 |
| SK40198A3 (en) | 1998-11-04 |
| EP0863704A4 (fr) | 2003-09-10 |
| WO1997011605A1 (fr) | 1997-04-03 |
| CZ92998A3 (cs) | 1998-09-16 |
| NO981386D0 (no) | 1998-03-26 |
| HUP9802651A3 (en) | 2001-08-28 |
| KR19990063672A (ko) | 1999-07-26 |
| NO981386L (no) | 1998-05-28 |
| PL325953A1 (en) | 1998-08-17 |
| TR199800573T2 (xx) | 1998-07-21 |
| BG102355A (en) | 1999-04-30 |
| NZ319891A (en) | 1999-01-28 |
| AU716497B2 (en) | 2000-02-24 |
| AU7251596A (en) | 1997-04-17 |
| CN1201369A (zh) | 1998-12-09 |
| JPH11512724A (ja) | 1999-11-02 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |