ATE411044T1 - Monozyte-spezifisches teilchenförmiges verabreichungsvehikel - Google Patents

Monozyte-spezifisches teilchenförmiges verabreichungsvehikel

Info

Publication number
ATE411044T1
ATE411044T1 AT02723679T AT02723679T ATE411044T1 AT E411044 T1 ATE411044 T1 AT E411044T1 AT 02723679 T AT02723679 T AT 02723679T AT 02723679 T AT02723679 T AT 02723679T AT E411044 T1 ATE411044 T1 AT E411044T1
Authority
AT
Austria
Prior art keywords
vector
applications
administration vehicle
monocytic
inventive
Prior art date
Application number
AT02723679T
Other languages
English (en)
Inventor
Thomas Wagner
Xianzhong Yu
Original Assignee
Ghc Res Dev Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ghc Res Dev Corp filed Critical Ghc Res Dev Corp
Application granted granted Critical
Publication of ATE411044T1 publication Critical patent/ATE411044T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AT02723679T 2001-03-30 2002-04-01 Monozyte-spezifisches teilchenförmiges verabreichungsvehikel ATE411044T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27976901P 2001-03-30 2001-03-30

Publications (1)

Publication Number Publication Date
ATE411044T1 true ATE411044T1 (de) 2008-10-15

Family

ID=23070360

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02723679T ATE411044T1 (de) 2001-03-30 2002-04-01 Monozyte-spezifisches teilchenförmiges verabreichungsvehikel

Country Status (9)

Country Link
US (1) US6875612B2 (de)
EP (1) EP1372704B1 (de)
JP (2) JP4430868B2 (de)
CN (2) CN101897983A (de)
AT (1) ATE411044T1 (de)
CA (1) CA2442682C (de)
DE (1) DE60229363D1 (de)
ES (1) ES2318002T3 (de)
WO (1) WO2002078733A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2525519A1 (en) * 2003-05-08 2004-12-02 Xcyte Therapies, Inc. Generation and isolation of antigen-specific t cells
US20100111985A1 (en) * 2007-04-25 2010-05-06 Orbis Health Solutions, Llc Vaccine compositions and methods of use
CA2685341A1 (en) * 2007-04-25 2008-11-06 Orbis Health Solutions Macrophage transfection method
WO2009032364A1 (en) * 2007-08-31 2009-03-12 Ghc Research Development Corporation Activation of nuclear factor-kappa b
EP2638896A1 (de) 2012-03-14 2013-09-18 Bioneer A/S Kationisches liposomales Arzneimittelabgabesystem für spezifisches Targeting humaner CD14+ Monozyten in Vollblut
WO2014078768A1 (en) * 2012-11-19 2014-05-22 Troyer Deryl L Leukocytes as delivery cells for imaging and disease therapy
BR112018010006A2 (pt) * 2015-11-18 2019-02-05 Orbis Health Solutions Llc sistema de expressão de gene, vetor, método para produção de uma célula-tronco pluripotente induzida e para tratamento de câncer, vacina, e, composição terapêutica.
KR20190086431A (ko) * 2016-08-17 2019-07-22 오르비스 헬스 솔루션즈 엘엘씨 종양-표적화 비드 벡터 및 그의 사용 방법
CN114555191A (zh) * 2019-05-29 2022-05-27 奥比思健康解决方案有限责任公司 用于表达嵌合受体的递送载体和颗粒及其使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL103059A0 (en) 1991-09-30 1993-02-21 Boehringer Ingelheim Int Conjugates for introducing nucleic acid into higher eucaryotic cells
HUP9802651A3 (en) 1995-09-28 2001-08-28 Univ Pittsburgh Stimulation of cell-mediated immune responses by targeted particulate genetic immunization
US6630169B1 (en) * 1999-03-31 2003-10-07 Nektar Therapeutics Particulate delivery systems and methods of use
EP1165754A1 (de) 1999-04-06 2002-01-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Pharmazeutische zusammensetzung enthaltend zirkulierende blutzellen, bevorzugt monocyten, und deren verwendung
US20020006412A1 (en) * 2000-04-28 2002-01-17 Roberts Bruce L. Preparation and use of particulates composed of adenovirus particles

Also Published As

Publication number Publication date
JP2005508843A (ja) 2005-04-07
CA2442682A1 (en) 2002-10-10
EP1372704A1 (de) 2004-01-02
CN101897983A (zh) 2010-12-01
EP1372704B1 (de) 2008-10-15
CN1512894B (zh) 2010-06-16
US20020155609A1 (en) 2002-10-24
JP4430868B2 (ja) 2010-03-10
DE60229363D1 (de) 2008-11-27
CN1512894A (zh) 2004-07-14
CA2442682C (en) 2011-08-02
US6875612B2 (en) 2005-04-05
JP2010031020A (ja) 2010-02-12
WO2002078733A1 (en) 2002-10-10
ES2318002T3 (es) 2009-05-01

Similar Documents

Publication Publication Date Title
Chen et al. Arginine signaling and cancer metabolism
Chen et al. Improved antigen cross-presentation by polyethyleneimine-based nanoparticles
BR9712988A (pt) Imunoterapia do câncer usando células tumorais combinadas com mistura de linfócitos
WO2010129023A3 (en) Supercharged proteins for cell penetration
DE60138641D1 (de) Herstellung von mikrokügelchen
ATE411044T1 (de) Monozyte-spezifisches teilchenförmiges verabreichungsvehikel
CY1113044T1 (el) Παραλλαγματα αντιγονου αρχεγονων κυτταρων προστατη (psca) και υποαλληλουχιες εξ αυτων
CY1112110T1 (el) Κυκλικο μοριο dna το οποιο διαθετει μια συμβατικη αφετηρια αντιγραφης, η διαδικασια παρασκευης του και η χρηση του στην γονιδιακη θεραπεια
WO2003093469A3 (en) Methods for delivering nucleic acid molecules into cells and assessment thereof
WO2006073748A3 (en) Antibodies against antigen presenting cells and uses thereof
WO2004074450A3 (en) Combination therapy for treating protein deficiencies
WO2008127285A3 (en) Target peptides for ovarian cancer immunotherapy
WO2005118864A3 (en) Antibodies and related molecules that bind to psca proteins
GB2386895B (en) An herpes simplex virus complex
MXPA02007899A (es) Citoquinas modificadas para utilizarse en terapia de cancer.
BRPI0510950A (pt) membro de ligação especìfico, composição farmacêutica, método para o tratamento de um tumor em um paciente, uso de um membro de ligação, produtos, ácido nucleico, e, carboidrato de sialiltetraosila
WO2003082330A1 (fr) Medicament therapeutique comprenant des nanoparticules proteiques creuses presentant un anticorps et nanoparticules proteiques creuses
TR200501460T3 (tr) Onkolitik virüsler kullanarak ağrı azaltma yöntemi
EP1778284A4 (de) Nukleinsäuren und entsprechende proteine 58p1d12 zur behandlung und zum nachweis von krebs
AU2002303340A8 (en) Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer
EP1908825A4 (de) Gegen pap2a gerichteter antikörper und dessen verwendung für diagnostische und therapeutische zwecke
EP1676590A4 (de) Onkogenes therapeutikum
WO2004041297A3 (en) Modified cytokines for use in cancer therapy
WO2006014234A3 (en) Novel recombinant poxvirus composition and uses thereof
WO2006055004A8 (en) Nucleic acids and corresponding proteins entitled 158p3d2 useful in treatment and detection of cancer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties