BRPI0510950A - membro de ligação especìfico, composição farmacêutica, método para o tratamento de um tumor em um paciente, uso de um membro de ligação, produtos, ácido nucleico, e, carboidrato de sialiltetraosila - Google Patents

membro de ligação especìfico, composição farmacêutica, método para o tratamento de um tumor em um paciente, uso de um membro de ligação, produtos, ácido nucleico, e, carboidrato de sialiltetraosila

Info

Publication number
BRPI0510950A
BRPI0510950A BRPI0510950-7A BRPI0510950A BRPI0510950A BR PI0510950 A BRPI0510950 A BR PI0510950A BR PI0510950 A BRPI0510950 A BR PI0510950A BR PI0510950 A BRPI0510950 A BR PI0510950A
Authority
BR
Brazil
Prior art keywords
binding member
carbohydrate
tumor
patient
products
Prior art date
Application number
BRPI0510950-7A
Other languages
English (en)
Inventor
Linda Gillian Durrant
Tina Parsons
Original Assignee
Scancell Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32526936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0510950(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scancell Ltd filed Critical Scancell Ltd
Publication of BRPI0510950A publication Critical patent/BRPI0510950A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3084—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

MEMBRO DE LIGAçãO ESPECìFICO, COMPOSIçãO FARMACêUTICA, MéTODO PARA O TRATAMENTO DE UM TUMOR EM UM PACIENTE, USO DE UM MEMBRO DE LIGAçãO, PRODUTOS, áCIDO NUCLéICO, E, CARBOIDRATO DE SIALILTETRAOSILA A presente invenção provê um membro de ligação específico isolado capaz de ligar um carboidrato de sialiltetraosila e diretamente induzir a morte celular sem a necessidade de células efetoras imunes. Este membro de ligação pode ser um anticorpo ou uma parte do mesmo. Também são providos o uso destes membros de ligação em medicina e ácidos nucleicos codificando estes membros de ligação.
BRPI0510950-7A 2004-05-12 2005-05-11 membro de ligação especìfico, composição farmacêutica, método para o tratamento de um tumor em um paciente, uso de um membro de ligação, produtos, ácido nucleico, e, carboidrato de sialiltetraosila BRPI0510950A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0410627.4A GB0410627D0 (en) 2004-05-12 2004-05-12 Specific binding members
PCT/GB2005/001805 WO2005108430A2 (en) 2004-05-12 2005-05-11 Monoclonal antibody sc104 and derivative thereof specifically binding to a sialyltetraosyl carbohydrate as a potential anti-tumor therapeutic agent

Publications (1)

Publication Number Publication Date
BRPI0510950A true BRPI0510950A (pt) 2007-11-20

Family

ID=32526936

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510950-7A BRPI0510950A (pt) 2004-05-12 2005-05-11 membro de ligação especìfico, composição farmacêutica, método para o tratamento de um tumor em um paciente, uso de um membro de ligação, produtos, ácido nucleico, e, carboidrato de sialiltetraosila

Country Status (17)

Country Link
US (2) US7915387B2 (pt)
EP (3) EP1745077B1 (pt)
JP (2) JP4944016B2 (pt)
KR (1) KR101213282B1 (pt)
CN (1) CN1961004B (pt)
AU (2) AU2005240837B2 (pt)
BR (1) BRPI0510950A (pt)
CA (1) CA2563516C (pt)
ES (1) ES2400571T3 (pt)
GB (1) GB0410627D0 (pt)
HK (1) HK1101696A1 (pt)
IL (1) IL178791A (pt)
MX (1) MXPA06012955A (pt)
NO (1) NO20065651L (pt)
NZ (3) NZ589214A (pt)
WO (1) WO2005108430A2 (pt)
ZA (1) ZA200609365B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0410627D0 (en) * 2004-05-12 2004-06-16 Scancell Ltd Specific binding members
SG173577A1 (en) * 2009-03-16 2011-09-29 Cephalon Australia Pty Ltd Humanised antibodies with anti-tumour activity
KR20120104558A (ko) 2009-11-05 2012-09-21 세파론 오스트레일리아 피티와이 엘티디 돌연변이형 ｋｒａｓ 또는 ｂｒａｆ 유전자를 포함하는 암을 치료하는 방법
ES2865068T3 (es) 2011-01-14 2021-10-14 Univ California Anticuerpos terapéuticos contra la proteína ROR-1 y métodos para usarlos
GB201319374D0 (en) 2013-11-01 2013-12-18 Univ Nottingham Glycans as functional cancer targets abd antibodies thereto
ES2924393T3 (es) * 2014-04-16 2022-10-06 Inst Nat Sante Rech Med Anticuerpos para la prevención o el tratamiento de episodios hemorrágicos

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JPS5811808A (ja) 1981-07-16 1983-01-22 Niles Parts Co Ltd 方位検出表示回路
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JPH09173063A (ja) 1995-12-26 1997-07-08 Cosmo Sogo Kenkyusho:Kk 抗ヒトリポタンパク質（ａ）モノクローナル抗体可変領域のＤＮＡ塩基配列およびアミノ酸配列
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Also Published As

Publication number Publication date
CN1961004B (zh) 2012-11-07
US8343490B2 (en) 2013-01-01
AU2005240837B2 (en) 2010-11-11
NO20065651L (no) 2007-02-06
CA2563516C (en) 2013-10-01
GB0410627D0 (en) 2004-06-16
JP2012105654A (ja) 2012-06-07
EP2392598A1 (en) 2011-12-07
JP2008502324A (ja) 2008-01-31
EP2397500A1 (en) 2011-12-21
AU2011200487B2 (en) 2012-11-01
EP1745077B1 (en) 2012-11-28
CN1961004A (zh) 2007-05-09
WO2005108430A3 (en) 2006-04-27
IL178791A (en) 2012-07-31
KR20070085116A (ko) 2007-08-27
CA2563516A1 (en) 2005-11-17
JP4944016B2 (ja) 2012-05-30
AU2011200487A1 (en) 2011-02-24
IL178791A0 (en) 2007-03-08
US20080118509A1 (en) 2008-05-22
ZA200609365B (en) 2008-05-28
US7915387B2 (en) 2011-03-29
KR101213282B1 (ko) 2012-12-17
ES2400571T3 (es) 2013-04-10
EP1745077A2 (en) 2007-01-24
AU2005240837A1 (en) 2005-11-17
NZ593171A (en) 2012-08-31
WO2005108430A2 (en) 2005-11-17
MXPA06012955A (es) 2007-04-25
NZ589214A (en) 2012-02-24
NZ550738A (en) 2011-03-31
HK1101696A1 (en) 2007-10-26
US20110212113A1 (en) 2011-09-01

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: ARANA THERAPEUTICS LIMITED (AU)

Free format text: TRANSFERIDO DE: SCANCELL LIMITED

B25D Requested change of name of applicant approved

Owner name: ARANA THERAPEUTICS PTY LTD. (AU)

Free format text: NOME ALTERADO DE: ARANA THERAPEUTICS LIMITED

B25D Requested change of name of applicant approved

Owner name: CEPHALON AUSTRALIA PTY LTD. (AU)

Free format text: NOME ALTERADO DE: ARANA THERAPEUTICS PTY LTD.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]