CA2232391A1 - Bifunctional sulfide-containing sulfonamide-chelating agents such as xsns for radioactive isotypes - Google Patents
Bifunctional sulfide-containing sulfonamide-chelating agents such as xsns for radioactive isotypes Download PDFInfo
- Publication number
- CA2232391A1 CA2232391A1 CA 2232391 CA2232391A CA2232391A1 CA 2232391 A1 CA2232391 A1 CA 2232391A1 CA 2232391 CA2232391 CA 2232391 CA 2232391 A CA2232391 A CA 2232391A CA 2232391 A1 CA2232391 A1 CA 2232391A1
- Authority
- CA
- Canada
- Prior art keywords
- ile
- leu
- asp
- phe
- val
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19536781.2 | 1995-09-21 | ||
DE1995136781 DE19536781A1 (de) | 1995-09-21 | 1995-09-21 | Bifunktionelle sulfidhaltige Sulfonamid-Chelatbildner vom Typ XSNS für radioaktive Isotope |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2232391A1 true CA2232391A1 (en) | 1997-03-27 |
Family
ID=7773888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2232391 Abandoned CA2232391A1 (en) | 1995-09-21 | 1996-09-19 | Bifunctional sulfide-containing sulfonamide-chelating agents such as xsns for radioactive isotypes |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0853488A2 (de) |
AU (1) | AU1435997A (de) |
CA (1) | CA2232391A1 (de) |
DE (1) | DE19536781A1 (de) |
WO (1) | WO1997010852A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19652374A1 (de) * | 1996-12-04 | 1998-06-10 | Schering Ag | Verwendung von Endothelin-Konjugaten in der Therapie, neue Endothelin-Konjugate, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung |
EP0946202B1 (de) * | 1996-10-28 | 2003-09-10 | Amersham Health AS | Kontrastmittel |
US6524553B2 (en) | 1998-03-31 | 2003-02-25 | Bristol-Myers Squibb Pharma Company | Quinolone vitronectin receptor antagonist pharmaceuticals |
AU5541799A (en) | 1998-03-31 | 1999-11-29 | Du Pont Pharmaceuticals Company | Pharmaceuticals for the imaging of angiogenic disorders |
US6548663B1 (en) | 1998-03-31 | 2003-04-15 | Bristol-Myers Squibb Pharma Company | Benzodiazepine vitronectin receptor antagonist pharmaceuticals |
US6537520B1 (en) | 1998-03-31 | 2003-03-25 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
US6794518B1 (en) | 1998-12-18 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
US6569402B1 (en) | 1998-12-18 | 2003-05-27 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
EP1140204A2 (de) | 1998-12-18 | 2001-10-10 | Du Pont Pharmaceuticals Company | Vitronektin-rezeptor antagonist arzeimittheln |
CA2349333A1 (en) | 1998-12-18 | 2000-06-22 | Du Pont Pharmaceuticals Company | Vitronectin receptor antagonist pharmaceuticals |
US6511649B1 (en) | 1998-12-18 | 2003-01-28 | Thomas D. Harris | Vitronectin receptor antagonist pharmaceuticals |
GB0105224D0 (en) | 2001-03-02 | 2001-04-18 | Nycomed Amersham Plc | Improved peptide-chelate conjugates |
WO2005044313A2 (en) * | 2003-11-06 | 2005-05-19 | Amersham Health As | Conjugates of angiotensin ii and an imaging moiety |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4310999C2 (de) * | 1993-03-31 | 1996-07-18 | Diagnostikforschung Inst | Bifunktionelle chalkogenatom-unterbrochene Chelatbildner vom Typ XN¶1¶S¶1¶X' für radioaktive Isotope und deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel |
DK0710228T3 (da) * | 1993-07-19 | 1998-09-21 | Resolution Pharm Inc | Hydraziner med N3S-konfiguration som radionuclidchelatorer |
EP0724601A4 (de) * | 1993-08-17 | 1999-02-03 | Neorx Corp | S 3n chelatierende verbindungen zur radiomarkierung von liganden, antiliganden oder anderen proteinen |
-
1995
- 1995-09-21 DE DE1995136781 patent/DE19536781A1/de not_active Withdrawn
-
1996
- 1996-09-19 WO PCT/DE1996/001821 patent/WO1997010852A2/de not_active Application Discontinuation
- 1996-09-19 AU AU14359/97A patent/AU1435997A/en not_active Abandoned
- 1996-09-19 CA CA 2232391 patent/CA2232391A1/en not_active Abandoned
- 1996-09-19 EP EP96945139A patent/EP0853488A2/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO1997010852A2 (de) | 1997-03-27 |
DE19536781A1 (de) | 1997-03-27 |
EP0853488A2 (de) | 1998-07-22 |
AU1435997A (en) | 1997-04-09 |
WO1997010852A3 (de) | 1997-08-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2921482B1 (de) | Markierte hemmer des prostataspezifischen membranantigens (psma), biologische beurteilung und verwendung als bildgebungsmittel | |
CA2232391A1 (en) | Bifunctional sulfide-containing sulfonamide-chelating agents such as xsns for radioactive isotypes | |
AU691806B2 (en) | Chelating agents of the type XN1S1O1 for radioactive isotopes, metal complexes thereof, and their use in diagnosis and therapy | |
CA2232340A1 (en) | Bifunctional nicotinamide-chelating agents such as n2s2 for radioactive isotopes | |
CA2232315A1 (en) | Bifunctional sulfide-containing sulfonamide-chelating agents such as s2 ny for radioactive isotopes | |
AU6501594A (en) | Bifunctional chelators and their use in radiopharmaceuticals | |
US6488909B1 (en) | Chelating agents as well as their tricarbonyl complexes with technetium and rhenium | |
AU2015203742A1 (en) | Labeled inhibitors of prostate specific membrane antigen (psma), biological evaluation, and use as imaging agents | |
AU692154B2 (en) | Chelators of type XN1S1X' for radioactive isotopes, their metal complexes and their diagnostic and therapeutical uses | |
US6143275A (en) | Type S3 N2 chelators for radioactive isotopes, their metal complexes and their diagnostic and therapeutical use | |
CA2232620A1 (en) | Bifunctional sulfide-containing sulfonamide-chelating agents such as xsny for radioactive isotopes | |
DE4425781A1 (de) | Technetium-Sulfonamid-Komplexe, deren Verwendung, diese enthaltende pharmazeutische Mittel, sowie Verfahren zur Herstellung der Komplexe und Mittel | |
HUT74881A (en) | N-alkyl peptide chelate formers, their metal comlexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compounds | |
WO1996007629A1 (en) | Technetium chelates to be used for determining the renal function |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |