CA2231528A1 - Procede de diagnostics de l'affection coeliaque - Google Patents

Procede de diagnostics de l'affection coeliaque Download PDF

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Publication number
CA2231528A1
CA2231528A1 CA 2231528 CA2231528A CA2231528A1 CA 2231528 A1 CA2231528 A1 CA 2231528A1 CA 2231528 CA2231528 CA 2231528 CA 2231528 A CA2231528 A CA 2231528A CA 2231528 A1 CA2231528 A1 CA 2231528A1
Authority
CA
Canada
Prior art keywords
cells
pos
antibody
ema
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2231528
Other languages
English (en)
Inventor
Donald George Weir
Christopher Alexander Whelan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2231528A1 publication Critical patent/CA2231528A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne un procédé de diagnostic d'affection coeliaque et d'états s'y rapportant chez un sujet pour lequel on connaît ou soupçonne l'existence d'un tel état. Le procédé consiste d'abord à mettre en contact un fluide physiologique, prélevé chez le sujet et contenant un anticorps spécifique de l'état considéré, avec une suspension de cellules d'une lignée cellulaire immortelle présentant un site épitopique spécifique de l'anticorps. Le procédé consiste ensuite à déterminer l'importance de la liaison de l'anticorps avec les cellules. Il est avéré que les cellules ombilicales humaines conviennent particulièrement pour ce procédé. L'utilisation d'une lignée cellulaire permet, par mise en culture de ces cellules, de préparer d'importantes quantités de matériau pour l'estimation d'anticorps et de les stocker pour usage ultérieur à un prix de revient très faible.
CA 2231528 1995-09-15 1996-09-13 Procede de diagnostics de l'affection coeliaque Abandoned CA2231528A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE950725 1995-09-15
IE950725 1995-09-15

Publications (1)

Publication Number Publication Date
CA2231528A1 true CA2231528A1 (fr) 1997-03-20

Family

ID=11040894

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2231528 Abandoned CA2231528A1 (fr) 1995-09-15 1996-09-13 Procede de diagnostics de l'affection coeliaque

Country Status (7)

Country Link
EP (1) EP0850418A1 (fr)
JP (1) JPH11511559A (fr)
AU (1) AU707114B2 (fr)
CA (1) CA2231528A1 (fr)
NO (1) NO981057L (fr)
NZ (1) NZ319260A (fr)
WO (1) WO1997010508A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6703208B1 (en) 1999-10-20 2004-03-09 Immco Diagnostics Immunological assay for detection of antibodies in celiac disease
ITRM20020144A1 (it) * 2002-03-15 2003-09-15 Dipartimento Di Scienze Biomed Metodo sierologico per rivelare l'atrofia dei villi intestinali in pazienti affetti da malattia celiaca.
ES2217931B1 (es) * 2002-07-01 2006-02-16 Universidad De Barcelona Metodo de diagnostico de la evolucion de la masa intestinal absortiva en un individuo.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL155894B1 (en) * 1987-12-23 1992-01-31 Przed Zagraniczne W Polsce Pla Test for assessing gluten-dependent enteropathies

Also Published As

Publication number Publication date
NO981057D0 (no) 1998-03-10
AU707114B2 (en) 1999-07-01
WO1997010508A1 (fr) 1997-03-20
EP0850418A1 (fr) 1998-07-01
JPH11511559A (ja) 1999-10-05
AU7143996A (en) 1997-04-01
NO981057L (no) 1998-03-10
NZ319260A (en) 1999-08-30

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