CA2228221C - Papillomavirus polyprotein constructs - Google Patents

Papillomavirus polyprotein constructs Download PDF

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Publication number
CA2228221C
CA2228221C CA2228221A CA2228221A CA2228221C CA 2228221 C CA2228221 C CA 2228221C CA 2228221 A CA2228221 A CA 2228221A CA 2228221 A CA2228221 A CA 2228221A CA 2228221 C CA2228221 C CA 2228221C
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CA
Canada
Prior art keywords
leu
thr
val
lys
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2228221A
Other languages
English (en)
French (fr)
Other versions
CA2228221A1 (en
Inventor
Elizabeth Ann Webb
Mary Brigid Margetts
John Cooper Cox
Ian Frazer
Nigel Alan John Mcmillan
Mark Philip Williams
Margaret Bridget Holland Moloney
Stirling John Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Queensland UQ
CSL Ltd
Original Assignee
University of Queensland UQ
CSL Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Queensland UQ, CSL Ltd filed Critical University of Queensland UQ
Publication of CA2228221A1 publication Critical patent/CA2228221A1/en
Application granted granted Critical
Publication of CA2228221C publication Critical patent/CA2228221C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2228221A 1995-07-27 1996-07-26 Papillomavirus polyprotein constructs Expired - Fee Related CA2228221C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPN4439A AUPN443995A0 (en) 1995-07-27 1995-07-27 Papillomavirus polyprotein
AU4439/95 1995-07-27
PCT/AU1996/000473 WO1997005164A1 (en) 1995-07-27 1996-07-26 Papillomavirus polyprotein constructs

Publications (2)

Publication Number Publication Date
CA2228221A1 CA2228221A1 (en) 1997-02-13
CA2228221C true CA2228221C (en) 2011-05-17

Family

ID=3788774

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2228221A Expired - Fee Related CA2228221C (en) 1995-07-27 1996-07-26 Papillomavirus polyprotein constructs

Country Status (8)

Country Link
US (2) US6365160B1 (cg-RX-API-DMAC7.html)
EP (2) EP1847549A3 (cg-RX-API-DMAC7.html)
JP (2) JPH11510688A (cg-RX-API-DMAC7.html)
AU (1) AUPN443995A0 (cg-RX-API-DMAC7.html)
CA (1) CA2228221C (cg-RX-API-DMAC7.html)
NZ (1) NZ313108A (cg-RX-API-DMAC7.html)
WO (1) WO1997005164A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA966381B (cg-RX-API-DMAC7.html)

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US6509149B2 (en) * 1995-06-06 2003-01-21 Hybridon, Inc. HPV-specific oligonucleotides
US6030771A (en) * 1997-08-25 2000-02-29 Centers For Disease Control And Prevention Mosaic protein and restriction endonuclease assisted ligation method for making the same
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
JP2002524078A (ja) * 1998-09-04 2002-08-06 アヴェンティス パスツール リミテット゛ 子宮頸がんの治療
US20050100928A1 (en) * 1999-09-16 2005-05-12 Zycos Inc., A Delaware Corporation Nucleic acids encoding polyepitope polypeptides
US7026443B1 (en) * 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
ATE418997T1 (de) * 2000-07-06 2009-01-15 Univ Georgetown Stabile (fixierte) formen von viralen l1 capsidproteinen, deren fusionsproteinen, und deren verwendungen
GB0017990D0 (en) * 2000-07-21 2000-09-13 Glaxo Group Ltd Papilloma virus sequences
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
CN101367869B (zh) 2000-09-30 2012-12-05 北京万泰生物药业股份有限公司 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗
AUPR446801A0 (en) 2001-04-18 2001-05-17 University Of Queensland, The Novel compositions and uses therefor
AU2003215244A1 (en) * 2002-02-14 2003-09-04 Curagen Corporation Complexes and methods of using same
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
AU2002950183A0 (en) * 2002-07-12 2002-09-12 The Council Of The Queensland Institute Of Medical Research Expression of hydrophobic proteins
AU2003282731B2 (en) 2002-10-03 2009-01-08 Wyeth Holdings Corporation Human papillomavirus polypeptides and immunogenic compositions
GB0222953D0 (en) * 2002-10-03 2002-11-13 Glaxo Group Ltd Novel Compounds
JP2006503914A (ja) * 2002-10-21 2006-02-02 エムジーアイ ファーマ バイオロジックス インコーポレイテッド ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法
WO2004098497A2 (en) * 2003-04-28 2004-11-18 Genencor International, Inc. Cd4+ human papillomavirus (hpv) epitopes
US20080160089A1 (en) * 2003-10-14 2008-07-03 Medivas, Llc Vaccine delivery compositions and methods of use
AU2005222776A1 (en) * 2003-12-31 2005-09-29 Genimmune N.V. Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
CA2590337C (en) 2004-12-15 2017-07-11 Neuralab Limited Humanized amyloid beta antibodies for use in improving cognition
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
WO2007038246A2 (en) * 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
JP2009524584A (ja) * 2005-12-07 2009-07-02 メディバス エルエルシー ポリマー−生物製剤送達組成物を構築するための方法
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
WO2009017467A1 (en) 2007-07-27 2009-02-05 Elan Pharma International Limited Treatment of amyloidogenic diseases
CA2649672C (en) * 2006-05-02 2015-07-07 Medivas, Llc Delivery of ophthalmologic agents to the exterior or interior of the eye
KR100904844B1 (ko) * 2006-08-28 2009-06-25 성균관대학교산학협력단 인유두종 바이러스(hpv)유전자를 포함하는자궁경부암의 치료 또는 예방용 dna 백신
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
EP2178944A1 (en) * 2007-07-24 2010-04-28 Medivas, LLC Biodegradable cationic polymer gene transfer compositions and methods of use
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
CN102186484A (zh) * 2008-08-13 2011-09-14 梅迪沃什有限公司 Aabb-聚(酯肽)可生物降解聚合物及其使用方法
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
CA2741762C (en) * 2008-10-31 2018-04-03 Trovagene, Inc. A genetic marker for detection of human papillomavirus
CA2653478A1 (en) * 2009-01-23 2010-07-23 Gregg Martin Automated wash system for industrial vehicles
US9050287B2 (en) * 2009-01-23 2015-06-09 The Trustees Of The University Of Pennsylvania Vaccines for human papilloma virus and methods for using the same
EP2723801B1 (en) 2011-06-23 2017-01-18 DSM IP Assets B.V. New biodegradable polyesteramide copolymers for drug delivery
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
WO2013055326A2 (en) * 2011-10-12 2013-04-18 The Trustees Of The University Of Pennsylvania Vaccines for human papilloma virus and methods for using the same
AU2014248535B2 (en) 2013-03-12 2017-03-30 Inovio Pharmaceuticals, Inc. Improved vaccines for human papilloma virus and methods for using the same
CN107106509B (zh) 2014-12-18 2021-11-30 帝斯曼知识产权资产管理有限公司 用于递送酸敏感药物的药物递送系统
SG11202008539YA (en) * 2018-03-06 2020-10-29 Precigen Inc Human papillomavirus vaccines and uses of the same
AU2021385551A1 (en) * 2020-11-25 2023-06-22 Precigen, Inc. Human papilloma virus vaccines and uses of the same for hpv associated diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
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FR2643817B1 (fr) * 1989-03-06 1993-12-17 Transgene Sa Composition pharmaceutique, utile a titre preventif ou curatif contre les tumeurs induites par les papillomavirus
KR910016343A (ko) * 1990-03-20 1991-11-05 스타인, 부그 사람 파필로마바이러스(hpv) 16 단백질의 혈청반응성 에피토프
DE4015044A1 (de) * 1990-05-10 1991-11-14 Behringwerke Ag Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18
CN1067382A (zh) * 1990-09-26 1992-12-30 布里斯托尔-迈尔斯斯奎尔公司 人类乳头状瘤病毒肽的表达以及在致免疫组合物中的应用
DE69131992T2 (de) * 1990-12-12 2000-06-29 Csl Ltd., Parkville Papillomavirusuntereinheit-impfstoff
US5464936A (en) 1990-12-21 1995-11-07 Cetus Oncology Corporation Compositions for identification of papillomavirus replication inhibitors
GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
GB9207701D0 (en) * 1992-04-08 1992-05-27 Cancer Res Campaign Tech Papillomavirus e7 protein
WO1994012629A1 (en) 1992-12-02 1994-06-09 Baylor College Of Medicine Episomal vectors for gene therapy
EP0769963A4 (en) * 1994-07-27 1999-07-28 Commw Scient Ind Res Org POLYEPITOPE VACCINES
DE4447664C2 (de) 1994-10-07 1999-04-15 Lutz Prof Dr Gissmann Fusionsproteine, Verfahren zu deren Herstellung sowie deren Anwendung
AUPN015794A0 (en) * 1994-12-20 1995-01-19 Csl Limited Variants of human papilloma virus antigens
US5955087A (en) * 1995-02-24 1999-09-21 Cantab Pharmaceuticals Research Limited Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation

Also Published As

Publication number Publication date
CA2228221A1 (en) 1997-02-13
JP2007054074A (ja) 2007-03-08
EP0840747A4 (en) 2002-10-23
EP1847549A3 (en) 2008-01-16
WO1997005164A1 (en) 1997-02-13
JPH11510688A (ja) 1999-09-21
ZA966381B (en) 1997-05-02
NZ313108A (en) 1999-05-28
US6726912B1 (en) 2004-04-27
AUPN443995A0 (en) 1995-08-17
US6365160B1 (en) 2002-04-02
EP1847549A2 (en) 2007-10-24
EP0840747A1 (en) 1998-05-13

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Effective date: 20150727