CA2223776C - Method of treatment for lung diseases using antisense oligonucleotides - Google Patents
Method of treatment for lung diseases using antisense oligonucleotides Download PDFInfo
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- CA2223776C CA2223776C CA002223776A CA2223776A CA2223776C CA 2223776 C CA2223776 C CA 2223776C CA 002223776 A CA002223776 A CA 002223776A CA 2223776 A CA2223776 A CA 2223776A CA 2223776 C CA2223776 C CA 2223776C
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/474,497 US5994315A (en) | 1995-06-07 | 1995-06-07 | Low adenosine agent, composition, kit and method for treatment of airway disease |
| US08/474,497 | 1995-06-07 | ||
| PCT/US1996/009306 WO1996040162A1 (en) | 1995-06-07 | 1996-06-06 | Method of treatment for lung diseases using antisense oligonucleotides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2223776A1 CA2223776A1 (en) | 1996-12-19 |
| CA2223776C true CA2223776C (en) | 2002-02-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002223776A Expired - Fee Related CA2223776C (en) | 1995-06-07 | 1996-06-06 | Method of treatment for lung diseases using antisense oligonucleotides |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5994315A (enExample) |
| EP (1) | EP0831848A4 (enExample) |
| JP (1) | JPH11507218A (enExample) |
| CN (1) | CN1134260C (enExample) |
| AU (1) | AU726468B2 (enExample) |
| CA (1) | CA2223776C (enExample) |
| WO (1) | WO1996040162A1 (enExample) |
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| US20030026782A1 (en) | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US7935675B1 (en) | 1994-07-15 | 2011-05-03 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6025339A (en) * | 1995-06-07 | 2000-02-15 | East Carolina University | Composition, kit and method for treatment of disorders associated with bronchoconstriction and lung inflammation |
| US6825174B2 (en) * | 1995-06-07 | 2004-11-30 | East Carolina University | Composition, formulations & method for prevention & treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) & inflammation |
| US6040296A (en) * | 1995-06-07 | 2000-03-21 | East Carolina University | Specific antisense oligonucleotide composition & method for treatment of disorders associated with bronchoconstriction and lung inflammation |
| US7034007B1 (en) | 1995-06-07 | 2006-04-25 | East Carolina University | Low adenosine anti-sense oligonucleotide, compositions, kit & method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) & surfactant depletion |
| AU738513B2 (en) * | 1997-02-28 | 2001-09-20 | University Of Iowa Research Foundation, The | Use of nucleic acids containing unmethylated CpG dinucleotide in the treatment of LPS-associated disorders |
| GB9718487D0 (en) * | 1997-09-02 | 1997-11-05 | Univ Sheffield | Pulmonary hypertension |
| EP1019065A4 (en) * | 1997-09-17 | 2002-02-20 | Univ East Carolina | NUCLEIC ACIDS HYBRIDIZING TO MULTIPLE TARGETS, THEIR PREPARATION, COMPOSITIONS, FORMULATION, KITS AND APPLICATIONS |
| US6046319A (en) * | 1997-10-22 | 2000-04-04 | University Technologies International, Inc. | Antisense oligodeoxynucleotides regulating expression of TNF-α |
| AU1616499A (en) * | 1997-12-01 | 1999-06-16 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Chemokine variants and methods of use |
| US6121023A (en) * | 1998-01-22 | 2000-09-19 | Akzo Nobel N.V. | Isothermal transcription based assay for the detection and quantification of the chemokine rantes |
| US6525185B1 (en) | 1998-05-07 | 2003-02-25 | Affymetrix, Inc. | Polymorphisms associated with hypertension |
| ATE335510T1 (de) | 1998-05-22 | 2006-09-15 | Ottawa Health Research Inst | Methoden und produkte zur induzierung mukosaler immunität |
| EP1011608A4 (en) * | 1998-06-08 | 2002-05-15 | Epigenesis Pharmaceuticals Inc | COMPOSITION AND METHOD FOR THE PREVENTION AND TREATMENT OF HEART AND NEUTRAL FAILURE OR DAMAGE RELATED TO ISCHEMIA, ENDOTOXIN RELEASE, ARDS OR CALLED BY THE ADDITION OF SPECIFIC MEDICINES |
| US7244714B1 (en) * | 1998-06-12 | 2007-07-17 | Aradigm Corporation | Methods of delivering aerosolized polynucleotides to the respiratory tract |
| CN1317009A (zh) * | 1998-08-03 | 2001-10-10 | 东卡罗来纳大学 | 低腺苷反义寡核苷酸制剂、组合物、试剂盒及处理 |
| US6080580A (en) * | 1998-10-05 | 2000-06-27 | Isis Pharmaceuticals Inc. | Antisense oligonucleotide modulation of tumor necrosis factor-α (TNF-α) expression |
| US6228642B1 (en) * | 1998-10-05 | 2001-05-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of tumor necrosis factor-(α) (TNF-α) expression |
| WO2000051621A1 (en) * | 1999-03-05 | 2000-09-08 | Epigenesis Pharmaceuticals, Inc. | Method for validating/invalidating target(s) and pathways |
| US6136603A (en) * | 1999-03-26 | 2000-10-24 | Isis Pharmaceuticals Inc. | Antisense modulation of interleukin-5 signal transduction |
| BR0006019A (pt) * | 1999-04-06 | 2001-03-13 | Univ East Carolina | Oligonucleotìdeo de anti-sentido de adenosina baixo, composições, kit & método para tratamento de distúrbios de vias aéreas associados com broncoconstricção, inflamação pulmonar, alergia(s) & depleção de surfactante |
| AU6336000A (en) * | 1999-06-17 | 2001-01-09 | Eastern Virginia Medical School | Treatment of viral influenza with antisense oligonucleotides |
| US7585847B2 (en) * | 2000-02-03 | 2009-09-08 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for the treatment of asthma and allergy |
| US20070026394A1 (en) * | 2000-02-11 | 2007-02-01 | Lawrence Blatt | Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies |
| US20070021360A1 (en) * | 2001-04-24 | 2007-01-25 | Nyce Jonathan W | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase |
| US20090247606A1 (en) * | 2001-08-28 | 2009-10-01 | Sirna Therapeutics, Inc. | RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
| ATE447967T1 (de) | 2001-09-14 | 2009-11-15 | Cytos Biotechnology Ag | Verpackung von immunstimulierendem cpg in virusähnlichen partikeln: herstellungsverfahren und verwendung |
| WO2004053104A2 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5’ cpg nucleic acids and methods of use |
| FR2848573B1 (fr) * | 2002-12-13 | 2005-04-08 | Exonhit Therapeutics Sa | Compositions et methodes pour la detection et le traitement de pathologies neurodegeneratives |
| EP2006298A3 (en) | 2003-04-15 | 2009-04-22 | Xenon Pharmaceuticals Inc. | Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof |
| US8153603B2 (en) | 2005-02-25 | 2012-04-10 | Isis Pharmaceuticals, Inc. | Compositions and their uses directed to IL-4R alpha |
| EP1973608A1 (en) | 2005-12-14 | 2008-10-01 | Cytos Biotechnology AG | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| NZ573622A (en) | 2006-06-12 | 2011-12-22 | Cytos Biotechnology Ag | Processes for packaging oligonucleotides into virus-like particles of rna bacteriophages |
| CA2718520C (en) | 2008-03-17 | 2020-01-07 | The Board Of Regents Of The University Of Texas System | Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration |
| US9399125B2 (en) | 2013-02-13 | 2016-07-26 | Becton, Dickinson And Company | Needleless connector and access port disinfection cleaner and antimicrobial protection cap |
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| US5248671A (en) * | 1989-02-15 | 1993-09-28 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
| US5087617A (en) * | 1989-02-15 | 1992-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
| US5514788A (en) * | 1993-05-17 | 1996-05-07 | Isis Pharmaceuticals, Inc. | Oligonucleotide modulation of cell adhesion |
| US5264618A (en) * | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| US5245022A (en) * | 1990-08-03 | 1993-09-14 | Sterling Drug, Inc. | Exonuclease resistant terminally substituted oligonucleotides |
| US5521291A (en) * | 1991-09-30 | 1996-05-28 | Boehringer Ingelheim International, Gmbh | Conjugates for introducing nucleic acid into higher eucaryotic cells |
| US5858784A (en) * | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| GB2264948B (en) * | 1992-03-13 | 1996-10-16 | Merck & Co Inc | Human adenosine receptors |
| WO1993020200A1 (en) * | 1992-04-02 | 1993-10-14 | Imperial Cancer Research Technology Limited | Modified cells and method of treatment |
| US5320962A (en) * | 1992-07-22 | 1994-06-14 | Duke University | DNA encoding the human A1 adenosine receptor |
| US5631237A (en) * | 1992-12-22 | 1997-05-20 | Dzau; Victor J. | Method for producing in vivo delivery of therapeutic agents via liposomes |
| US6040296A (en) * | 1995-06-07 | 2000-03-21 | East Carolina University | Specific antisense oligonucleotide composition & method for treatment of disorders associated with bronchoconstriction and lung inflammation |
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1996
- 1996-06-06 AU AU60959/96A patent/AU726468B2/en not_active Ceased
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- 1996-06-06 EP EP96918260A patent/EP0831848A4/en not_active Withdrawn
- 1996-06-06 JP JP9501658A patent/JPH11507218A/ja not_active Ceased
- 1996-06-06 CN CNB961961155A patent/CN1134260C/zh not_active Expired - Fee Related
Also Published As
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|---|---|
| JPH11507218A (ja) | 1999-06-29 |
| CN1192686A (zh) | 1998-09-09 |
| EP0831848A4 (en) | 2002-03-27 |
| MX9709866A (es) | 1998-08-30 |
| AU726468B2 (en) | 2000-11-09 |
| WO1996040162A1 (en) | 1996-12-19 |
| HK1015705A1 (en) | 1999-10-22 |
| CN1134260C (zh) | 2004-01-14 |
| EP0831848A1 (en) | 1998-04-01 |
| AU6095996A (en) | 1996-12-30 |
| CA2223776A1 (en) | 1996-12-19 |
| US5994315A (en) | 1999-11-30 |
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