CA2219202A1 - Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts - Google Patents

Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts Download PDF

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Publication number
CA2219202A1
CA2219202A1 CA002219202A CA2219202A CA2219202A1 CA 2219202 A1 CA2219202 A1 CA 2219202A1 CA 002219202 A CA002219202 A CA 002219202A CA 2219202 A CA2219202 A CA 2219202A CA 2219202 A1 CA2219202 A1 CA 2219202A1
Authority
CA
Canada
Prior art keywords
prosthesis
support structure
pump
tubular member
seeding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002219202A
Other languages
English (en)
French (fr)
Inventor
Alvin Peterson
Lee K. Landeen
Joan Zeltinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advanced Tissue Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2219202A1 publication Critical patent/CA2219202A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/24—Apparatus using programmed or automatic operation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/06—Tubular
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Clinical Laboratory Science (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002219202A 1995-04-27 1996-04-09 Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts Abandoned CA2219202A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43076895A 1995-04-27 1995-04-27
US430,768 1995-04-27

Publications (1)

Publication Number Publication Date
CA2219202A1 true CA2219202A1 (en) 1996-10-31

Family

ID=23708945

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002219202A Abandoned CA2219202A1 (en) 1995-04-27 1996-04-09 Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts

Country Status (7)

Country Link
EP (1) EP0822978A4 (de)
JP (1) JP4059301B2 (de)
KR (1) KR19990008070A (de)
AU (1) AU703117B2 (de)
CA (1) CA2219202A1 (de)
NZ (1) NZ306304A (de)
WO (1) WO1996034090A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109804059A (zh) * 2016-08-03 2019-05-24 诺斯威克公园医学研究所有限公司 生物反应器以及处理生物材料的方法

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
EP2075015B1 (de) * 1997-07-03 2015-03-11 Massachusetts Institute of Technology Gewebegezüchtete Konstrukte
US6066495A (en) * 1998-03-05 2000-05-23 Tissue Engineering, Inc. Methods and apparatus for the conditioning of ligament replacement tissue
WO2002032224A1 (en) * 2000-10-06 2002-04-25 Dancu Michael B System and method to simulate hemodynamics
EP1205541A1 (de) * 2000-11-14 2002-05-15 Klaus Dr. Giehl Verfahren zur Langzeit-Kultivierung organotypischer Slices von Gehirn und anderen Geweben postnataler, insbesondere adulter Säuger
JP2002315566A (ja) 2001-04-24 2002-10-29 Takagi Ind Co Ltd 細胞・組織培養装置
JP2003061642A (ja) * 2001-08-30 2003-03-04 Takagi Ind Co Ltd 細胞・組織培養装置
EP1495108A2 (de) * 2002-04-08 2005-01-12 Millenium Biologix Inc. Automatisierte vorrichtung zum gewebeaufbau
JP4061149B2 (ja) * 2002-07-24 2008-03-12 株式会社ティッシュエンジニアリングイニシアティブ 細胞培養装置および細胞培養方法
JP2006223317A (ja) * 2003-05-15 2006-08-31 Univ Waseda 細胞播種方法
JP2006223101A (ja) * 2003-05-15 2006-08-31 Univ Waseda 生体組織の保持装置及びこれを用いた生体組織処理装置
GB0410177D0 (en) * 2004-05-07 2004-06-09 Univ Wales Medicine Engineered tubular tissue structures
DE102005049905A1 (de) * 2005-10-17 2007-04-19 Medizinische Hochschule Hannover Verfahren und Vorrichtung zur Herstellung eines Gelenkersatzes
JP5433129B2 (ja) 2006-07-10 2014-03-05 パーパス株式会社 細胞又は組織の培養方法
JP4981374B2 (ja) 2006-07-10 2012-07-18 パーパス株式会社 細胞又は組織の培養装置及び培養方法
AU2007283465A1 (en) * 2006-08-11 2008-02-14 The University Of Queensland Scaffold treatment - device and method
US8058057B2 (en) * 2008-05-30 2011-11-15 Corning Incorporated Cell culture apparatus and method
SG184798A1 (en) * 2010-05-17 2012-11-29 Univ Yale System for seeding cells onto three dimensional scaffolds
US9090863B2 (en) 2010-05-17 2015-07-28 Pall Corporation System for seeding cells onto three dimensional scaffolds
CN105296433B (zh) 2014-08-01 2018-02-09 中山康方生物医药有限公司 一种ctla4抗体、其药物组合物及其用途
KR102231394B1 (ko) 2016-05-19 2021-03-24 코지 사이토 배양 장치 및 배양 방법, 및 이 배양 방법에 의해 제조된 배양 장기
WO2018035710A1 (en) 2016-08-23 2018-03-01 Akeso Biopharma, Inc. Anti-ctla4 antibodies
US20200078160A1 (en) * 2016-11-07 2020-03-12 Sharklet Technologies, Inc. Vascular grafts, method of manufacturing thereof and articles comprising the same
WO2021111642A1 (ja) * 2019-12-06 2021-06-10 ティシューバイネット株式会社 管状細胞構造体の培養方法
CA3189196A1 (en) * 2020-07-09 2022-01-13 Novoheart International Limited Support and system for engineered tissue

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4050893A (en) * 1974-07-22 1977-09-27 Hancock Laboratories, Inc. Arrangement for preparing natural tissue for implantation
US4015590A (en) * 1976-04-12 1977-04-05 Baylor College Of Medicine Balloon activated blood pump
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
US4911713A (en) * 1986-03-26 1990-03-27 Sauvage Lester R Method of making vascular prosthesis by perfusion
NZ222089A (en) * 1986-10-20 1993-03-26 Malcolm B Herring Endothelial cell harvester with irrigation means for enzyme treatment of blood vessel
CH671683A5 (de) * 1987-03-05 1989-09-29 Sulzer Ag
US4990131A (en) * 1987-09-01 1991-02-05 Herbert Dardik Tubular prostheses for vascular reconstructive surgery and process for preparing same
CH675679A5 (de) * 1987-12-07 1990-10-31 Sulzer Ag
JP2678945B2 (ja) * 1989-04-17 1997-11-19 有限会社ナイセム 人工血管とその製造方法及び人工血管用基質
EP0571527B1 (de) * 1991-02-14 1996-04-24 Baxter International Inc. Herstellungsverfahren für biegsame biologische Gewebeverpflanzungsmaterialen
GB9116036D0 (en) * 1991-07-25 1991-09-11 Univ Leicester Preparing grafts for implantation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109804059A (zh) * 2016-08-03 2019-05-24 诺斯威克公园医学研究所有限公司 生物反应器以及处理生物材料的方法

Also Published As

Publication number Publication date
JP4059301B2 (ja) 2008-03-12
EP0822978A1 (de) 1998-02-11
WO1996034090A1 (en) 1996-10-31
JPH11504216A (ja) 1999-04-20
AU703117B2 (en) 1999-03-18
AU5484396A (en) 1996-11-18
KR19990008070A (ko) 1999-01-25
NZ306304A (en) 1999-03-29
EP0822978A4 (de) 1999-08-18

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20030409