CA2213620A1 - Anticorps pour la detection de hla-g - Google Patents

Anticorps pour la detection de hla-g

Info

Publication number
CA2213620A1
CA2213620A1 CA002213620A CA2213620A CA2213620A1 CA 2213620 A1 CA2213620 A1 CA 2213620A1 CA 002213620 A CA002213620 A CA 002213620A CA 2213620 A CA2213620 A CA 2213620A CA 2213620 A1 CA2213620 A1 CA 2213620A1
Authority
CA
Canada
Prior art keywords
hla
antibody
polypeptide
seq
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002213620A
Other languages
English (en)
Inventor
Susan J. Fisher
Michael T. Mcmaster
Caroline Damsky
Clifford Librach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2213620A1 publication Critical patent/CA2213620A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La molécule HLA-G de classe I est spécifiquement exprimée par des cytotrophoblastes invasifs. L'invention décrit des antigènes qui élicitent des anticorps spécifiques de HLA-G et des anticorps qui fixent ces antigènes. L'invention décrit également des procédés liés à la mesure des taux de HLA-G dans les liquides biologiques.
CA002213620A 1995-04-07 1996-03-21 Anticorps pour la detection de hla-g Abandoned CA2213620A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41964895A 1995-04-07 1995-04-07
US08/419,648 1995-04-07

Publications (1)

Publication Number Publication Date
CA2213620A1 true CA2213620A1 (fr) 1996-10-10

Family

ID=23663133

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002213620A Abandoned CA2213620A1 (fr) 1995-04-07 1996-03-21 Anticorps pour la detection de hla-g

Country Status (5)

Country Link
EP (1) EP0819171A1 (fr)
JP (1) JPH11503320A (fr)
AU (1) AU696118B2 (fr)
CA (1) CA2213620A1 (fr)
WO (1) WO1996031604A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105675883A (zh) * 2016-02-22 2016-06-15 叶尚勉 一种检测人类白细胞抗原hla-g的方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2760023B1 (fr) 1997-02-21 2004-05-07 Commissariat Energie Atomique Cellules eucaryotes exprimant a leur surface au moins une isoforme d'hla-g et leurs applications
FR2775294B1 (fr) * 1998-02-20 2000-12-01 Commissariat Energie Atomique Methode de selection de tumeurs sensibles a un traitement anticancereux et ses applications
CA2321222A1 (fr) 1998-02-20 1999-08-26 Commissariat A L'energie Atomique Methode de selection de tumeurs exprimant hla-g, sensibles a un traitement anticancereux et ses applications
EP1056886A1 (fr) * 1998-02-25 2000-12-06 National University of Ireland, Cork Gene de susceptibilite a la pre-eclampsie et aux fausses-couches lie au hla
FR2794977B1 (fr) * 1999-06-18 2003-10-31 Commissariat Energie Atomique Utilisation de compositions contenant des formes solubles d'hla-g dans le traitement de pathologies inflammatoires de la peau, et leur procede d'obtention
EP1224465B1 (fr) 1999-09-27 2005-12-21 Clifford L. Librach Detection de hla-g
FR2810047B1 (fr) * 2000-06-13 2004-04-02 Commissariat Energie Atomique Nouvelle isoforme d'hla-g et ses applications
GB0507755D0 (en) * 2005-04-16 2005-05-25 Univ Sheffield Cytotrophoblast stem cells
PT2183361E (pt) * 2007-07-27 2015-09-11 Immatics Biotechnologies Gmbh Nova imunoterapia para tumores neuronais e cerebrais
NZ582822A (en) * 2007-07-27 2012-06-29 Immatics Biotechnologies Gmbh Novel immunogenic epitopes for immunotherapy
FR2953023B1 (fr) * 2009-11-23 2011-12-09 Commissariat Energie Atomique Utilisation d'une isoforme d'hla-g comme marqueur de l'osteogenese
WO2016160622A2 (fr) * 2015-03-27 2016-10-06 University Of Southern California Hla-g en tant que nouvelle cible pour l'immunothérapie par lymphocytes t car
EA201892793A1 (ru) 2016-06-03 2019-06-28 Инвектис Анти-hla-g специфические антитела
US11492387B2 (en) * 2018-05-09 2022-11-08 Tianjin Dongya Biological Technology Co., Ltd. Broad spectrum vaccine, preparing method and application thereof
AU2019328677A1 (en) 2018-08-31 2021-04-01 Invectys SA Chimeric antigen receptors against multiple HLA-G isoforms
EA202190609A1 (ru) 2018-09-27 2021-08-17 Тизона Терапьютикс Антитела против hla-g, композиции, содержащие антитела против hla-g, и способы применения антител против hla-g

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0412700T3 (da) * 1989-08-03 1998-04-06 Univ California Fremgangsmåde til isolering af føtale cytrophoblastceller

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105675883A (zh) * 2016-02-22 2016-06-15 叶尚勉 一种检测人类白细胞抗原hla-g的方法
CN105675883B (zh) * 2016-02-22 2018-08-31 叶尚勉 一种检测人类白细胞抗原hla-g的方法

Also Published As

Publication number Publication date
WO1996031604A1 (fr) 1996-10-10
AU696118B2 (en) 1998-09-03
EP0819171A1 (fr) 1998-01-21
AU5256896A (en) 1996-10-23
JPH11503320A (ja) 1999-03-26

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Legal Events

Date Code Title Description
FZDE Dead