CA2212162A1 - Liposomes that contain contrast media for the visualization of intravascular space - Google Patents

Liposomes that contain contrast media for the visualization of intravascular space

Info

Publication number
CA2212162A1
CA2212162A1 CA 2212162 CA2212162A CA2212162A1 CA 2212162 A1 CA2212162 A1 CA 2212162A1 CA 2212162 CA2212162 CA 2212162 CA 2212162 A CA2212162 A CA 2212162A CA 2212162 A1 CA2212162 A1 CA 2212162A1
Authority
CA
Canada
Prior art keywords
active ingredient
liposome formulation
containing liposome
liposomes
cholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2212162
Other languages
English (en)
French (fr)
Inventor
Andreas Sachse
Georg Rossling
Jens Leike
Werner Krause
Gabriele Schuhmann-Giampieri
Peter Muschick
Wolf-Rudiger Press
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2212162A1 publication Critical patent/CA2212162A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA 2212162 1995-02-09 1996-02-09 Liposomes that contain contrast media for the visualization of intravascular space Abandoned CA2212162A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19505813 1995-02-09
DE19505813.5 1995-02-09

Publications (1)

Publication Number Publication Date
CA2212162A1 true CA2212162A1 (en) 1996-08-15

Family

ID=7754530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2212162 Abandoned CA2212162A1 (en) 1995-02-09 1996-02-09 Liposomes that contain contrast media for the visualization of intravascular space

Country Status (7)

Country Link
EP (1) EP0806969A2 (no)
JP (1) JPH10513466A (no)
AU (1) AU4789096A (no)
CA (1) CA2212162A1 (no)
DE (1) DE19606326A1 (no)
NO (1) NO973666L (no)
WO (1) WO1996024381A2 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19529922A1 (de) * 1995-08-01 1997-02-06 Schering Ag Verwendung von liposomalen Zubereitungen in der indirekten MRT-Lymphographie
GB9624918D0 (en) * 1996-11-29 1997-01-15 Nycomed Imaging As Particulate components
KR100824068B1 (ko) * 2000-04-28 2008-04-21 후지필름 홀딩스 가부시끼가이샤 소수성 요오드 화합물을 함유하는 리포솜
EP1772156A1 (en) * 2004-07-21 2007-04-11 Konica Minolta Medical & Graphic, Inc. Liposome-containing x-ray radiopaque dye and process for producing the same
EP1776948B1 (en) * 2004-08-11 2015-12-09 Konica Minolta Medical & Graphic, Inc. Method of producing liposome-containing preparation
EP2606912A1 (en) * 2011-12-23 2013-06-26 Central Medical Service Co., Ltd. Contrast medium composition with contrast enhancement effect by comprising highly concentrated agent

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK482685D0 (da) * 1984-10-22 1985-10-21 Hope Nat Medical Center Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
WO1990004943A1 (en) * 1988-11-09 1990-05-17 Unger Evan C Liposomal radiologic contrast agents
DE3922005A1 (de) * 1989-06-30 1991-01-10 Schering Ag Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung
DE3934656A1 (de) * 1989-10-13 1991-04-18 Schering Ag Verfahren zur herstellung von waessrigen dispersionen
ATE210426T1 (de) * 1992-10-14 2001-12-15 Liposome Co Inc Interdigitation-fusionsliposomen und gels
EP0665756A1 (de) * 1992-10-16 1995-08-09 SACHSE, Andreas Verfahren und vorrichtung zur herstellung flüssiger, disperser systeme
DE4341472A1 (de) * 1993-12-02 1995-06-08 Schering Ag Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
DE4426438A1 (de) * 1994-07-26 1996-02-01 Schering Ag Verwendung von Chelaten als Röntgenkontrastmittel

Also Published As

Publication number Publication date
WO1996024381A2 (de) 1996-08-15
NO973666L (no) 1997-10-08
WO1996024381A3 (de) 1996-10-03
EP0806969A2 (de) 1997-11-19
JPH10513466A (ja) 1998-12-22
AU4789096A (en) 1996-08-27
DE19606326A1 (de) 1996-08-22
NO973666D0 (no) 1997-08-08

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Legal Events

Date Code Title Description
FZDE Dead