CA2211621A1 - Methods and compositions for regulation of cd28 expression - Google Patents
Methods and compositions for regulation of cd28 expressionInfo
- Publication number
- CA2211621A1 CA2211621A1 CA002211621A CA2211621A CA2211621A1 CA 2211621 A1 CA2211621 A1 CA 2211621A1 CA 002211621 A CA002211621 A CA 002211621A CA 2211621 A CA2211621 A CA 2211621A CA 2211621 A1 CA2211621 A1 CA 2211621A1
- Authority
- CA
- Canada
- Prior art keywords
- oligomer
- cells
- seq
- oligomers
- bases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
- C12N2310/151—Nucleic acids forming more than 2 strands, e.g. TFOs more than 3 strands, e.g. tetrads, H-DNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/18—Type of nucleic acid acting by a non-sequence specific mechanism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38704195A | 1995-02-09 | 1995-02-09 | |
| US08/387,041 | 1995-02-09 | ||
| US08/529,878 US5932556A (en) | 1995-09-17 | 1995-09-17 | Methods and compositions for regulation of CD28 expression |
| US08/529,878 | 1995-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2211621A1 true CA2211621A1 (en) | 1996-08-15 |
Family
ID=27011718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002211621A Abandoned CA2211621A1 (en) | 1995-02-09 | 1996-02-05 | Methods and compositions for regulation of cd28 expression |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JP2002515013A (cs) |
| KR (1) | KR100258826B1 (cs) |
| CN (1) | CN1181021A (cs) |
| AU (1) | AU703139B2 (cs) |
| CA (1) | CA2211621A1 (cs) |
| CZ (1) | CZ250097A3 (cs) |
| SK (1) | SK108697A3 (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007530057A (ja) * | 2004-03-31 | 2007-11-01 | ライオンズ アイ インスティチュート リミテッド | Ｖｅｇｆ転写物の安定性を調節するための治療的分子 |
| KR101802540B1 (ko) * | 2009-09-25 | 2017-11-28 | 큐알엔에이, 인크. | Ｆｌｇ의 발현 및 활성을 조절함으로써 필라그린(ｆｌｇ)에 관련된 질환의 치료 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923799A (en) * | 1984-02-06 | 1990-05-08 | The Ontario Cancer Institute | T cell specific cDNA clone |
| US5254638A (en) * | 1991-03-25 | 1993-10-19 | The Reagents Of The University Of California | Composite materials of interpenetrating inorganic and organic polymer networks |
| GB9310842D0 (en) * | 1993-05-26 | 1993-07-14 | Imperial College | Gene identification |
-
1996
- 1996-02-05 SK SK1086-97A patent/SK108697A3/sk unknown
- 1996-02-05 CN CN96193197A patent/CN1181021A/zh active Pending
- 1996-02-05 KR KR1019970705496A patent/KR100258826B1/ko not_active Expired - Fee Related
- 1996-02-05 CA CA002211621A patent/CA2211621A1/en not_active Abandoned
- 1996-02-05 AU AU52958/96A patent/AU703139B2/en not_active Ceased
- 1996-02-05 CZ CZ972500A patent/CZ250097A3/cs unknown
- 1996-02-05 JP JP52435696A patent/JP2002515013A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SK108697A3 (en) | 1998-04-08 |
| JP2002515013A (ja) | 2002-05-21 |
| CN1181021A (zh) | 1998-05-06 |
| CZ250097A3 (cs) | 1998-01-14 |
| AU5295896A (en) | 1996-08-27 |
| MX9705963A (es) | 1998-08-30 |
| AU703139B2 (en) | 1999-03-18 |
| KR100258826B1 (ko) | 2000-07-01 |
| KR19980702101A (ko) | 1998-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |