CA2210337C - Resolution of racemates of 2-aryl-2-alkyl-.omega.-alkylaminoalkane-nitriles - Google Patents

Resolution of racemates of 2-aryl-2-alkyl-.omega.-alkylaminoalkane-nitriles Download PDF

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Publication number
CA2210337C
CA2210337C CA002210337A CA2210337A CA2210337C CA 2210337 C CA2210337 C CA 2210337C CA 002210337 A CA002210337 A CA 002210337A CA 2210337 A CA2210337 A CA 2210337A CA 2210337 C CA2210337 C CA 2210337C
Authority
CA
Canada
Prior art keywords
racemates
alkyl
optically active
resolution
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002210337A
Other languages
English (en)
French (fr)
Other versions
CA2210337A1 (en
Inventor
Ulrich Karl
Werner Seitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Abbott GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott GmbH and Co KG filed Critical Abbott GmbH and Co KG
Publication of CA2210337A1 publication Critical patent/CA2210337A1/en
Application granted granted Critical
Publication of CA2210337C publication Critical patent/CA2210337C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002210337A 1995-01-31 1996-01-20 Resolution of racemates of 2-aryl-2-alkyl-.omega.-alkylaminoalkane-nitriles Expired - Fee Related CA2210337C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19502967.4 1995-01-31
DE19502967A DE19502967A1 (de) 1995-01-31 1995-01-31 Verfahren zur Racemattrennung von 2-Aryl-2-omega-alkylaminoalkannitrilen
PCT/EP1996/000236 WO1996023764A1 (de) 1995-01-31 1996-01-20 VERFAHREN ZUR RACEMATTRENNUNG VON 2-ARYL-2-ALKYL-φ-ALKYLAMINO-ALKANNITRILEN

Publications (2)

Publication Number Publication Date
CA2210337A1 CA2210337A1 (en) 1996-08-08
CA2210337C true CA2210337C (en) 2004-04-27

Family

ID=7752720

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002210337A Expired - Fee Related CA2210337C (en) 1995-01-31 1996-01-20 Resolution of racemates of 2-aryl-2-alkyl-.omega.-alkylaminoalkane-nitriles

Country Status (13)

Country Link
US (1) US5786498A (de)
EP (1) EP0808302B1 (de)
JP (1) JPH10512890A (de)
CN (1) CN1068871C (de)
AT (1) ATE191464T1 (de)
CA (1) CA2210337C (de)
DE (2) DE19502967A1 (de)
DK (1) DK0808302T3 (de)
ES (1) ES2145427T3 (de)
GR (1) GR3033164T3 (de)
MX (1) MX9705200A (de)
PT (1) PT808302E (de)
WO (1) WO1996023764A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130302A (en) 1996-08-19 2000-10-10 Northwestern University Synthesis and use of (polyfluoroaryl)fluoroanions of aluminum, gallium and indium

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2059985C3 (de) * 1970-12-05 1979-10-04 Knoll Ag, 6700 Ludwigshafen Rechtsdrehende, basisch substituierte Phenylacetonitrile, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3642331A1 (de) * 1986-12-11 1988-06-23 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel
DE3723684A1 (de) * 1987-07-17 1989-01-26 Basf Ag Verfahren zur herstellung der enantiomeren von verapamil
IT1226902B (it) * 1988-07-12 1991-02-21 Mini Ricerca Scient Tecnolog Processo per la sintesi del levodopa
SE8803012L (sv) * 1988-08-29 1990-03-01 Skf Nova Ab Anordning foer aastadkommande av bromsning av ett vridmomentoeverfoerande organ
WO1992007821A1 (en) * 1990-11-01 1992-05-14 G.D. Searle & Co. Diastereoisomers of bicyclo-substituted phenylacetonitrile derivatives
DE4203547A1 (de) * 1992-02-07 1993-08-12 Knoll Ag Verfahren zur racemattrennung von verapamil
GB9319918D0 (en) * 1993-09-27 1993-11-10 Chiros Ltd Chiral compounds and their preparation

Also Published As

Publication number Publication date
ATE191464T1 (de) 2000-04-15
DK0808302T3 (da) 2000-07-17
DE19502967A1 (de) 1996-08-01
CN1068871C (zh) 2001-07-25
CN1172470A (zh) 1998-02-04
DE59604890D1 (de) 2000-05-11
US5786498A (en) 1998-07-28
EP0808302A1 (de) 1997-11-26
EP0808302B1 (de) 2000-04-05
MX9705200A (es) 1997-10-31
GR3033164T3 (en) 2000-08-31
ES2145427T3 (es) 2000-07-01
CA2210337A1 (en) 1996-08-08
PT808302E (pt) 2000-09-29
JPH10512890A (ja) 1998-12-08
WO1996023764A1 (de) 1996-08-08

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