CA2198790A1 - Test pour diagnostiquer l'hemochromatose - Google Patents
Test pour diagnostiquer l'hemochromatoseInfo
- Publication number
- CA2198790A1 CA2198790A1 CA 2198790 CA2198790A CA2198790A1 CA 2198790 A1 CA2198790 A1 CA 2198790A1 CA 2198790 CA2198790 CA 2198790 CA 2198790 A CA2198790 A CA 2198790A CA 2198790 A1 CA2198790 A1 CA 2198790A1
- Authority
- CA
- Canada
- Prior art keywords
- hemochromatosis
- iron
- test
- uibc
- serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000012360 testing method Methods 0.000 title description 12
- 208000018565 Hemochromatosis Diseases 0.000 title description 11
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 16
- 229910052742 iron Inorganic materials 0.000 description 8
- 210000002966 serum Anatomy 0.000 description 8
- 239000003153 chemical reaction reagent Substances 0.000 description 7
- 238000012216 screening Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 4
- 102000008133 Iron-Binding Proteins Human genes 0.000 description 3
- 108010035210 Iron-Binding Proteins Proteins 0.000 description 3
- 102000004338 Transferrin Human genes 0.000 description 3
- 108090000901 Transferrin Proteins 0.000 description 3
- 206010018910 Haemolysis Diseases 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000012581 transferrin Substances 0.000 description 2
- JHZUHSZHIROHQX-UHFFFAOYSA-N 4-[3-pyridin-2-yl-1-(4-sulfophenyl)-2,4-dihydro-1,3,5-triazin-6-yl]benzenesulfonic acid Chemical compound N1=C(C=CC=C1)N1CN=C(N(C1)C1=CC=C(C=C1)S(=O)(=O)O)C1=CC=C(C=C1)S(=O)(=O)O JHZUHSZHIROHQX-UHFFFAOYSA-N 0.000 description 1
- 208000022309 Alcoholic Liver disease Diseases 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 206010019663 Hepatic failure Diseases 0.000 description 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 208000025341 autosomal recessive disease Diseases 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007882 cirrhosis Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 description 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 150000002505 iron Chemical class 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 208000007903 liver failure Diseases 0.000 description 1
- 231100000835 liver failure Toxicity 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/90—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving iron binding capacity of blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2198790 CA2198790A1 (fr) | 1997-02-28 | 1997-02-28 | Test pour diagnostiquer l'hemochromatose |
| PCT/CA1998/000174 WO1998038515A1 (fr) | 1997-02-28 | 1998-03-02 | Test de depistage de l'hematochromatose |
| AU62865/98A AU6286598A (en) | 1997-02-28 | 1998-03-02 | Test for hemochromatosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2198790 CA2198790A1 (fr) | 1997-02-28 | 1997-02-28 | Test pour diagnostiquer l'hemochromatose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2198790A1 true CA2198790A1 (fr) | 1998-08-28 |
Family
ID=4160069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2198790 Abandoned CA2198790A1 (fr) | 1997-02-28 | 1997-02-28 | Test pour diagnostiquer l'hemochromatose |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU6286598A (fr) |
| CA (1) | CA2198790A1 (fr) |
| WO (1) | WO1998038515A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3269101A (en) * | 1999-11-12 | 2001-06-06 | James C. Barton | Diagnostic test for hemochromatosis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS529160B2 (fr) * | 1972-04-12 | 1977-03-14 | ||
| IT1100475B (it) * | 1978-11-08 | 1985-09-28 | R C O Ricerche Di Chimica Clin | Metodo e composizioni per la determinazione diretta del ferro mel stero ematico |
| JPS6069557A (ja) * | 1983-09-26 | 1985-04-20 | Wako Pure Chem Ind Ltd | 不飽和鉄結合能の測定方法 |
| DE3729502A1 (de) * | 1987-09-03 | 1989-03-23 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur bestimmung von eisen |
| EP0570588B1 (fr) * | 1991-12-02 | 1998-09-09 | Oriental Yeast Co., Ltd. | Procédé et réactif pour la détermination du fer sérique ou de la capacité de fixation du fer insaturé à l'aide d'aconitase |
-
1997
- 1997-02-28 CA CA 2198790 patent/CA2198790A1/fr not_active Abandoned
-
1998
- 1998-03-02 WO PCT/CA1998/000174 patent/WO1998038515A1/fr active Application Filing
- 1998-03-02 AU AU62865/98A patent/AU6286598A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6286598A (en) | 1998-09-18 |
| WO1998038515A1 (fr) | 1998-09-03 |
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| MANUAL | Medizym® ICAscreen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |