CA2184631A1 - Product and process for regulating signal transduction pathways - Google Patents
Product and process for regulating signal transduction pathwaysInfo
- Publication number
- CA2184631A1 CA2184631A1 CA002184631A CA2184631A CA2184631A1 CA 2184631 A1 CA2184631 A1 CA 2184631A1 CA 002184631 A CA002184631 A CA 002184631A CA 2184631 A CA2184631 A CA 2184631A CA 2184631 A1 CA2184631 A1 CA 2184631A1
- Authority
- CA
- Canada
- Prior art keywords
- peptide
- motif
- amino acid
- kinase
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
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- C12N2710/16011—Herpesviridae
- C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
- C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
- C12N2740/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
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- Transplantation (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US21511694A | 1994-03-17 | 1994-03-17 | |
US215,116 | 1994-03-17 |
Publications (1)
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CA2184631A1 true CA2184631A1 (en) | 1995-09-21 |
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Application Number | Title | Priority Date | Filing Date |
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CA002184631A Abandoned CA2184631A1 (en) | 1994-03-17 | 1995-03-17 | Product and process for regulating signal transduction pathways |
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EP (1) | EP0804218A1 (cs) |
JP (1) | JPH09512704A (cs) |
CA (1) | CA2184631A1 (cs) |
WO (1) | WO1995024915A1 (cs) |
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US5976819A (en) * | 1995-11-21 | 1999-11-02 | National Jewish Medical And Research Center | Product and process to regulate actin polymerization in T lymphocytes |
JP2001503260A (ja) * | 1996-10-23 | 2001-03-13 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 改良されたワクチン |
US6420338B1 (en) * | 1997-06-13 | 2002-07-16 | New York University Medical Center | Inhibition of the Src kinase family pathway as a method of treating HBV infection and hepatocellular carcinoma |
EP1156826B1 (en) | 1999-02-25 | 2009-05-27 | National Jewish Center For Immunology And Respiratory Medicine | Product and method for treatment of conditions associated with receptor-desensitization |
WO2003006060A1 (fr) * | 2001-07-09 | 2003-01-23 | Kyowa Hakko Kogyo Co., Ltd. | Inhibiteurs de la liaison au domaine sh3 |
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AU667803B2 (en) * | 1991-01-18 | 1996-04-18 | New York University | A receptor tyrosine kinase target protein cDNA cloning method and hGRB proteins |
CA2054602C (en) * | 1991-10-31 | 2003-04-22 | Anthony Pawson | Method for assaying for a substance that affects an sh2-phosphorylated ligand regulatory system |
US5770396A (en) * | 1992-04-16 | 1998-06-23 | The United States Of America As Represented By The Department Of Health And Human Services | Isolation characterization, and use of the human beta subunit of the high affinity receptor for immunoglobulin E |
IL101769A (en) * | 1992-05-03 | 2007-02-11 | Yeda Res & Dev | Modulation of TNF receptor action |
WO1994017095A1 (en) * | 1993-01-29 | 1994-08-04 | Ariad Pharmaceuticals, Inc. | Analogs of receptor tyrosine activation motifs and therapeutic uses thereof |
WO1994018832A1 (en) * | 1993-02-26 | 1994-09-01 | Dana-Farber Cancer Institute, Inc. | Cd4 mediated modulation of lipid kinases |
CN1056153C (zh) * | 1993-06-30 | 2000-09-06 | 法玛西雅厄普约翰公司 | 有丝分裂发生和运动发生的肽抑制物 |
DE69534920T2 (de) * | 1994-07-22 | 2007-04-05 | University Of North Carolina | Src SH3 BINDENDE PEPTIDE UND VERFAHREN ZU IHRER ISOLIERUNG UND VERWENDUNG |
AU5296796A (en) * | 1995-02-28 | 1996-09-18 | National Jewish Center For Immunology And Respiratory Function | Peptidyl compounds comprising an itim motif which regulate hematopoietic function and their use |
US7815749B2 (en) * | 2006-06-29 | 2010-10-19 | Hitachi Metals, Ltd. | Method for manufacturing semi-hard magnetic material and semi-hard magnetic material |
-
1995
- 1995-03-17 EP EP95914756A patent/EP0804218A1/en not_active Withdrawn
- 1995-03-17 JP JP7524210A patent/JPH09512704A/ja active Pending
- 1995-03-17 CA CA002184631A patent/CA2184631A1/en not_active Abandoned
- 1995-03-17 WO PCT/US1995/003438 patent/WO1995024915A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH09512704A (ja) | 1997-12-22 |
AU699662B2 (en) | 1998-12-10 |
WO1995024915A1 (en) | 1995-09-21 |
EP0804218A4 (cs) | 1997-11-12 |
AU2187495A (en) | 1995-10-03 |
EP0804218A1 (en) | 1997-11-05 |
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