CA2183329A1 - Procede de traitement et d'inhibition des ulceres gastriques et duodenaux - Google Patents
Procede de traitement et d'inhibition des ulceres gastriques et duodenauxInfo
- Publication number
- CA2183329A1 CA2183329A1 CA002183329A CA2183329A CA2183329A1 CA 2183329 A1 CA2183329 A1 CA 2183329A1 CA 002183329 A CA002183329 A CA 002183329A CA 2183329 A CA2183329 A CA 2183329A CA 2183329 A1 CA2183329 A1 CA 2183329A1
- Authority
- CA
- Canada
- Prior art keywords
- galactose
- oligosaccharide
- group
- stomach
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne un procédé traitant et/ou inhibant les ulcères gastriques ou duodénaux par administration d'une composition pharmaceutique comprenant un oligosaccharide de la formule (I): NeuAc-.alpha.(2-3)-pGal-.beta.(1)-(-X-)¿m?-(-Y-)¿n?-)¿p?-Z. Dans cette formule générale (I), X représente une liaison chimique ou un groupe pouvant lier le p galactose soit au groupe de liaison Y, soit au support multivalent Z; où l'oxygène glycosidique C¿1? du galactose est remplaçable par N, S ou C; Y représente un groupe de liaison; Z représente un support multivalent; m est un entier valant 0 ou 1; n est un entier valant 0 ou 1; et p est un entier valant de 2 à 1000. L'invention concerne en outre un procédé traitant et/ou inhibant les ulcères gastriques et duodénaux par administration d'une composition pharmaceutique comprenant un oligosaccharide, de la formule (II): NeuAc-.alpha.(2-3)-pGal-.beta.(1)-A. Dans cette formule (II), A représente un groupe pouvant se lier au p galactose; l'oxygène glycosidique C¿1? du galactose étant remplaçable par N, S ou C.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20451594A | 1994-03-02 | 1994-03-02 | |
US204,515 | 1994-03-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2183329A1 true CA2183329A1 (fr) | 1995-09-08 |
Family
ID=22758224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002183329A Abandoned CA2183329A1 (fr) | 1994-03-02 | 1995-03-02 | Procede de traitement et d'inhibition des ulceres gastriques et duodenaux |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0749314A4 (fr) |
JP (1) | JP3179108B2 (fr) |
AU (1) | AU709149B2 (fr) |
CA (1) | CA2183329A1 (fr) |
WO (1) | WO1995023605A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5736533A (en) * | 1995-06-07 | 1998-04-07 | Neose Technologies, Inc. | Bacterial inhibition with an oligosaccharide compound |
KR20000010732A (ko) * | 1996-05-03 | 2000-02-25 | 스티븐 로쓰 | 시알릴올리고당의 비스무트염 및 이를 사용한위궤양 및 십이지장궤양 치료 및 억제 방법 |
EP1165097B1 (fr) * | 1999-02-01 | 2007-05-02 | Dermal Research Laboratories, Inc. | Composition pharmaceutique d'hydrates de carbone complexes l'utilisation de celle-ci |
SE9901007D0 (sv) * | 1999-03-19 | 1999-03-19 | Thomas Boren | Use of fucosylated sialylated N-acetyl lactosamin carbohydrate structures for inhibition of bacterial adherence |
US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
FI20021989A0 (fi) * | 2002-11-06 | 2002-11-06 | Halina Miller-Podraza | Korkean affiniteetin Helicobacter pylori-reseptorit ja niiden käyttö |
NL2007931C2 (en) * | 2011-12-07 | 2013-06-10 | Friesland Brands Bv | Methods for providing sialylated oligosaccharides and products obtainable thereby. |
WO2020060260A1 (fr) * | 2018-09-20 | 2020-03-26 | 가톨릭대학교 산학협력단 | Composite polymère pour la reconnaissance de l'helicobacter pylori et composition pour la thérapie photodynamique la comprenant |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE464687B (sv) * | 1987-11-10 | 1991-06-03 | Biocarb Ab | Foerfarande foer framstaellning av en gelprodukt |
US5089479A (en) * | 1988-11-28 | 1992-02-18 | Krivan Howard C | Adhesion of mycoplasma pneumoniae and mycoplasma hominus to sulfatide |
US5260280A (en) * | 1989-02-07 | 1993-11-09 | Snow Brand Milk Products Co., Ltd. | Bacterial toxin neutralizer |
JPH0436294A (ja) * | 1990-06-01 | 1992-02-06 | Snow Brand Milk Prod Co Ltd | 牛乳由来の新規なガングリオシド及びその製造法 |
US5211937A (en) * | 1990-07-30 | 1993-05-18 | Glycomed Incorporated | Method of determining a site of inflammation utilizing elam-1 ligands |
US5164374A (en) * | 1990-12-17 | 1992-11-17 | Monsanto Company | Use of oligosaccharides for treatment of arthritis |
US5254676A (en) * | 1991-11-22 | 1993-10-19 | E. I. Du Pont De Nemours And Company | Oligosaccharide inhibitors for influenza virus |
EP0630251A1 (fr) * | 1992-03-19 | 1994-12-28 | University Of British Columbia | Procede et composition permettant de supprimer les effets secondaires de medicaments anti-inflammatoires |
AU4055993A (en) * | 1992-05-15 | 1993-12-13 | University Of British Columbia, The | N-acetyl glucosamine as gastroprotective agent |
AU4993893A (en) * | 1992-07-31 | 1994-03-03 | Neose Pharmaceuticals, Inc. | Compositions for treating and inhibiting gastric and duodenal ulcers |
-
1995
- 1995-03-02 WO PCT/US1995/002388 patent/WO1995023605A1/fr not_active Application Discontinuation
- 1995-03-02 JP JP52295595A patent/JP3179108B2/ja not_active Expired - Fee Related
- 1995-03-02 CA CA002183329A patent/CA2183329A1/fr not_active Abandoned
- 1995-03-02 AU AU19323/95A patent/AU709149B2/en not_active Ceased
- 1995-03-02 EP EP95911945A patent/EP0749314A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0749314A4 (fr) | 2002-09-18 |
AU1932395A (en) | 1995-09-18 |
AU709149B2 (en) | 1999-08-19 |
JP3179108B2 (ja) | 2001-06-25 |
EP0749314A1 (fr) | 1996-12-27 |
WO1995023605A1 (fr) | 1995-09-08 |
JPH09509931A (ja) | 1997-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |