CA2153071A1 - Derives de calcitonines - Google Patents
Derives de calcitoninesInfo
- Publication number
- CA2153071A1 CA2153071A1 CA2153071A CA2153071A CA2153071A1 CA 2153071 A1 CA2153071 A1 CA 2153071A1 CA 2153071 A CA2153071 A CA 2153071A CA 2153071 A CA2153071 A CA 2153071A CA 2153071 A1 CA2153071 A1 CA 2153071A1
- Authority
- CA
- Canada
- Prior art keywords
- derivatized
- molecules
- calcitonins
- calcitonin
- disclosed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000055006 Calcitonin Human genes 0.000 abstract 2
- 108060001064 Calcitonin Proteins 0.000 abstract 2
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 2
- 229960004015 calcitonin Drugs 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57527—Calcitonin gene related peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99974992A | 1992-12-31 | 1992-12-31 | |
| US07/999,749 | 1992-12-31 | ||
| PCT/US1993/012692 WO1994015962A2 (fr) | 1992-12-31 | 1993-12-30 | Derives calcitonines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2153071A1 true CA2153071A1 (fr) | 1994-07-21 |
| CA2153071C CA2153071C (fr) | 2000-05-30 |
Family
ID=25546645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002153071A Expired - Fee Related CA2153071C (fr) | 1992-12-31 | 1993-12-30 | Derives de calcitonines |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0677062A1 (fr) |
| JP (1) | JPH08505393A (fr) |
| KR (1) | KR100310280B1 (fr) |
| AU (1) | AU673237B2 (fr) |
| CA (1) | CA2153071C (fr) |
| FI (1) | FI953255A (fr) |
| NO (1) | NO952608L (fr) |
| NZ (1) | NZ261052A (fr) |
| WO (1) | WO1994015962A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962270A (en) | 1996-02-06 | 1999-10-05 | Bionebraska, Inc. | Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1806135A1 (de) * | 1967-11-09 | 1969-07-17 | Ciba Geigy | Neue hypocalcaemische Peptide und Verfahren zu ihrer Herstellung |
| US3956260A (en) * | 1967-11-09 | 1976-05-11 | Ciba-Geigy Corporation | Hypocalcaemic peptides and processes for their manufacture |
| CH523868A (de) * | 1969-10-22 | 1972-06-15 | Ciba Geigy Ag | Verfahren zur Herstellung neuer Dotriacontapeptidamide und ihrer Derivate |
| NL8602950A (nl) * | 1985-12-04 | 1987-07-01 | Sandoz Ag | Calcitonine-derivaten en werkwijzen voor het bereiden van deze derivaten en van farmaceutische preparaten die ze bevatten. |
| EP0297159A1 (fr) * | 1987-07-01 | 1989-01-04 | Armour Pharmaceutical Company | [N-Acyl, 1,7-Di-alanine]calcitonines, leur méthode de préparation, leurs compositions pharmaceutiques et emploi |
| DE3876022T2 (de) * | 1987-07-08 | 1993-04-22 | Mitsubishi Petrochemical Co | Calcitonin-derivate und deren salze. |
-
1993
- 1993-12-30 KR KR1019950702713A patent/KR100310280B1/ko not_active IP Right Cessation
- 1993-12-30 AU AU59629/94A patent/AU673237B2/en not_active Ceased
- 1993-12-30 NZ NZ261052A patent/NZ261052A/en unknown
- 1993-12-30 WO PCT/US1993/012692 patent/WO1994015962A2/fr not_active Application Discontinuation
- 1993-12-30 EP EP94905569A patent/EP0677062A1/fr not_active Ceased
- 1993-12-30 JP JP6516111A patent/JPH08505393A/ja active Pending
- 1993-12-30 CA CA002153071A patent/CA2153071C/fr not_active Expired - Fee Related
-
1995
- 1995-06-29 NO NO952608A patent/NO952608L/no not_active Application Discontinuation
- 1995-06-30 FI FI953255A patent/FI953255A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08505393A (ja) | 1996-06-11 |
| AU673237B2 (en) | 1996-10-31 |
| NO952608L (no) | 1995-08-30 |
| KR960700273A (ko) | 1996-01-19 |
| EP0677062A1 (fr) | 1995-10-18 |
| WO1994015962A2 (fr) | 1994-07-21 |
| NZ261052A (en) | 1997-10-24 |
| NO952608D0 (no) | 1995-06-29 |
| KR100310280B1 (ko) | 2002-02-28 |
| WO1994015962A3 (fr) | 1994-09-29 |
| FI953255A0 (fi) | 1995-06-30 |
| CA2153071C (fr) | 2000-05-30 |
| FI953255A (fi) | 1995-06-30 |
| AU5962994A (en) | 1994-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |