CA2146319A1 - Polyamine derivatives as anti-cytomegaloviral agents - Google Patents

Polyamine derivatives as anti-cytomegaloviral agents

Info

Publication number
CA2146319A1
CA2146319A1 CA002146319A CA2146319A CA2146319A1 CA 2146319 A1 CA2146319 A1 CA 2146319A1 CA 002146319 A CA002146319 A CA 002146319A CA 2146319 A CA2146319 A CA 2146319A CA 2146319 A1 CA2146319 A1 CA 2146319A1
Authority
CA
Canada
Prior art keywords
bis
compound
formula
propyl
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002146319A
Other languages
English (en)
French (fr)
Inventor
A. Stanley Tyms
Ronald D. Snyder
Terry L. Bowlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2146319A1 publication Critical patent/CA2146319A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
CA002146319A 1992-10-05 1993-09-10 Polyamine derivatives as anti-cytomegaloviral agents Abandoned CA2146319A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929220921A GB9220921D0 (en) 1992-10-05 1992-10-05 Polyamine derivatives as anticytomegaloviral agents
GB9220921.2 1992-10-05

Publications (1)

Publication Number Publication Date
CA2146319A1 true CA2146319A1 (en) 1994-04-14

Family

ID=10722983

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002146319A Abandoned CA2146319A1 (en) 1992-10-05 1993-09-10 Polyamine derivatives as anti-cytomegaloviral agents

Country Status (9)

Country Link
EP (1) EP0662829A1 (ja)
JP (1) JPH08512279A (ja)
KR (1) KR950703335A (ja)
AU (1) AU4854793A (ja)
CA (1) CA2146319A1 (ja)
GB (1) GB9220921D0 (ja)
HU (1) HUT72663A (ja)
NZ (1) NZ256254A (ja)
WO (1) WO1994007480A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831001A (en) * 1990-10-24 1998-11-03 Allelix Biopharmaceuticals Inc. Treatment of herpesvirus infection
WO1995009832A1 (en) * 1993-10-07 1995-04-13 Merrell Dow Pharmaceuticals Inc. Novel process for preparing polyamine derivatives and intermediates thereof
FR2749845B1 (fr) * 1996-06-18 1998-08-21 Oreal Nouveaux derives benzyl substitue(s) de polyalkylene-polyamines et leur utilisation dans des compositions cosmetiques et pharmaceutiques
WO2003013245A1 (en) 2001-08-07 2003-02-20 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
JP2005506354A (ja) 2001-10-16 2005-03-03 スリル バイオメディカル コーポレイション 癌治療のためのオリゴアミン化合物およびその誘導体
CA3089388A1 (en) * 2018-01-30 2019-08-08 Sun Biopharma, Inc. Methods for producing (6s,15s)-3,8,13,18-tetraazaicosane-6,15-diol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA903804B (en) * 1989-05-23 1991-03-27 Merrell Dow Pharma A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Also Published As

Publication number Publication date
KR950703335A (ko) 1995-09-20
AU4854793A (en) 1994-04-26
HU9500982D0 (en) 1995-06-28
JPH08512279A (ja) 1996-12-24
HUT72663A (en) 1996-05-28
NZ256254A (en) 1997-04-24
EP0662829A1 (en) 1995-07-19
WO1994007480A1 (en) 1994-04-14
GB9220921D0 (en) 1992-11-18

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 19980910