CA2137755C - Attenuation des troubles a cellules falciformes par le phenyluree, le benzyluree ou le phenylethyluree ou par un homologue a substituant methoxyl, methyl ou hydroxyl sur le noyau - Google Patents

Attenuation des troubles a cellules falciformes par le phenyluree, le benzyluree ou le phenylethyluree ou par un homologue a substituant methoxyl, methyl ou hydroxyl sur le noyau Download PDF

Info

Publication number
CA2137755C
CA2137755C CA 2137755 CA2137755A CA2137755C CA 2137755 C CA2137755 C CA 2137755C CA 2137755 CA2137755 CA 2137755 CA 2137755 A CA2137755 A CA 2137755A CA 2137755 C CA2137755 C CA 2137755C
Authority
CA
Canada
Prior art keywords
urea
para
sickle cell
benzylurea
phenylurea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA 2137755
Other languages
English (en)
Other versions
CA2137755A1 (fr
Inventor
William H. Waugh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2137755A1 publication Critical patent/CA2137755A1/fr
Application granted granted Critical
Publication of CA2137755C publication Critical patent/CA2137755C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA 2137755 1994-06-07 1994-12-09 Attenuation des troubles a cellules falciformes par le phenyluree, le benzyluree ou le phenylethyluree ou par un homologue a substituant methoxyl, methyl ou hydroxyl sur le noyau Expired - Fee Related CA2137755C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25575594A 1994-06-07 1994-06-07
US08/255,755 1994-06-07

Publications (2)

Publication Number Publication Date
CA2137755A1 CA2137755A1 (fr) 1995-12-08
CA2137755C true CA2137755C (fr) 2002-07-02

Family

ID=22969714

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2137755 Expired - Fee Related CA2137755C (fr) 1994-06-07 1994-12-09 Attenuation des troubles a cellules falciformes par le phenyluree, le benzyluree ou le phenylethyluree ou par un homologue a substituant methoxyl, methyl ou hydroxyl sur le noyau

Country Status (2)

Country Link
CA (1) CA2137755C (fr)
GB (1) GB2290235B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696475B2 (en) 1997-04-22 2004-02-24 Neurosearch A/S Substituted phenyl derivatives, their preparation and use
AP2001002103A0 (en) * 1998-10-22 2001-03-31 Neurosearch As Substituted phenyl derivatives, their preparation and use.
DE102012007558A1 (de) 2012-04-14 2013-10-17 Alf Hammes Gabe substituierter bis-aryl-harnstoffderivate zur behandlung von anämien

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56131516A (en) * 1980-03-18 1981-10-15 Koutaku Hayashi Immunochemotherapy, prevention of resistance to drug, and carcinostatic agent

Also Published As

Publication number Publication date
GB9500442D0 (en) 1995-03-01
GB2290235B (en) 1998-03-25
GB2290235A (en) 1995-12-20
CA2137755A1 (fr) 1995-12-08

Similar Documents

Publication Publication Date Title
CA2096036C (fr) Methode de stimulation de la synthese intracellulaire du glutathion a l&#39;aide d&#39;esters de l-2-oxothiazolidine-4-carboxylate
RU2573990C2 (ru) Препарат, содержащий аминокислоты и растения, и его активность при алкогольной детоксикации
Crippen The role of sedation in the ICU patient with pain and agitation
KR20120092152A (ko) 타액선 기능장애의 치료
EP3124023A1 (fr) Préparation durable sous forme de produit injectable de mélatonine stable à long terme
US20080234361A1 (en) Pharmaceutical Compositions, Methods of Formulation Thereof and Methods of Use Thereof
JPS61151123A (ja) 安定化された３―オキシゲルミルプロピオン酸ポリマーを有効成分とする免疫調整剤
EP2147671A1 (fr) Composition comprenant de la l-carnitine ou ses dérivés et son utilisation
US3069321A (en) Choline salicylate composition and methods of use
CA2137755C (fr) Attenuation des troubles a cellules falciformes par le phenyluree, le benzyluree ou le phenylethyluree ou par un homologue a substituant methoxyl, methyl ou hydroxyl sur le noyau
US5512573A (en) Use of phthaloylhydrazide derivatives as anti-hypoxic and defensive agents
KR950002884B1 (ko) 아세트알데히드의 독성을 감소시키는 조성물
Machabert et al. Methaemoglobinaemia due to amyl nitrite inhalation: a case report
JP3429507B2 (ja) 脳水腫の治療のためのトラセミドの使用
RU2760324C1 (ru) Новое применение полоксамера в качестве фармакологически активного вещества
CA2083825A1 (fr) Nouvelle composition pharmaceutique a base de taurine pour l&#39;administration par inhalation
JP3253878B2 (ja) 鉄キレート化用製剤、その製剤の製法及び地中海貧血症の治療法
WO1998013036A1 (fr) Compositions pharmaceutiques renfermant des derives de s-alkylisothiouronium
CN111939158A (zh) 光千金藤碱及其衍生物在制备治疗神经退行性疾病的药物中的应用
JPS58192821A (ja) 脳神経細胞の酸素欠乏性疾患の治療剤
KR101213600B1 (ko) 데커신 및/또는 데커시놀 안젤레이트, 또는 데커신및/또는 데커시놀 안젤레이트를 유효성분으로 하는당귀추출물을 포함하는 신기능 치료제 조성물
CN109718199B (zh) 一种用于缺血缺氧性脑损伤的经胃肠道给药药物及其用途
EP4205734A1 (fr) Application de l&#39;?-asarone dans la préparation de médicaments pour la prévention ou le traitement d&#39;un accident vasculaire cérébral hémorragique
CN109364067B (zh) 一种化合物在制备提高血脑屏障通透性药物中的用途
JPH0129168B2 (fr)

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed