CA2128242A1 - Moulded Bodies, in Particular Pellets, Containing One or More Plant Extracts, and the Pharmaceutical or Cosmetic Use of Such Pellets - Google Patents

Moulded Bodies, in Particular Pellets, Containing One or More Plant Extracts, and the Pharmaceutical or Cosmetic Use of Such Pellets

Info

Publication number
CA2128242A1
CA2128242A1 CA 2128242 CA2128242A CA2128242A1 CA 2128242 A1 CA2128242 A1 CA 2128242A1 CA 2128242 CA2128242 CA 2128242 CA 2128242 A CA2128242 A CA 2128242A CA 2128242 A1 CA2128242 A1 CA 2128242A1
Authority
CA
Canada
Prior art keywords
pellets
plant extract
plant
gelatin
skeleton builder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2128242
Other languages
French (fr)
Other versions
CA2128242C (en
Inventor
Jens-Christian Wunderlich
Ursula Schick
Jurgen Werry
Jurgen Freidenreich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfatec Pharma GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4201172A external-priority patent/DE4201172C1/en
Priority claimed from DE4201179A external-priority patent/DE4201179A1/en
Application filed by Individual filed Critical Individual
Publication of CA2128242A1 publication Critical patent/CA2128242A1/en
Application granted granted Critical
Publication of CA2128242C publication Critical patent/CA2128242C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A61K8/0225—Granulated powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706—Algae
    • A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Shaped articles containing plant extract(s), in particular pellets, are formed by dispersing the plant extract(s) in a matrix predominantly composed of a skeleton builder, i.e. collagen, gelatin, fractionated gelatin, a collagen hydrolysate, a gelatin derivative, plant protein or plant protein hydrolysate. They are storage-stable, and their pharmacological and cosmetic characteristics are essentially unaltered in comparison with the native extract. They are prepared by a simple process in which liquid plant extract(s) is(are) mixed or emulsified in a solution of the skeleton builder, or solid extracts are dissolved or suspended in a solution of the skeleton builder, the dispersion of skeleton builder and plant extract(s) is added dropwise to an intensely cold, inert, liquefied gas, preferably liquid nitrogen, thus shaping the pellets, and the shaped pellets are dried. The plant extract employed is preferably Aloe vera juice.
CA002128242A 1992-01-17 1993-01-18 Moulded bodies, in particular pellets, containing one or more plant extracts, and the pharmaceutical or cosmetic use of such pellets Expired - Fee Related CA2128242C (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE4201172A DE4201172C1 (en) 1992-01-17 1992-01-17 Pellets contg. Aloe vera extract - useful, e.g. as antiinflammatory of antibiotic agents, or for treating gastric ulcers
DEP4201179.5 1992-01-17
DEP4201172.8 1992-01-17
DE4201179A DE4201179A1 (en) 1992-01-17 1992-01-17 Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc.
US07/876,866 US5401502A (en) 1992-01-17 1992-04-30 Pellets containing plant extracts, process of making same and their pharmaceutical peroral or cosmetic use
US07/876,876 US5387415A (en) 1992-01-17 1992-04-30 Aloe vera juice containing pellets process for production thereof and the use thereof as pharmaceutical, cosmetic and peroral agents
US07/876,876 1992-04-30
US07/876,866 1992-04-30

Publications (2)

Publication Number Publication Date
CA2128242A1 true CA2128242A1 (en) 1993-07-22
CA2128242C CA2128242C (en) 1998-09-22

Family

ID=27435368

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002128242A Expired - Fee Related CA2128242C (en) 1992-01-17 1993-01-18 Moulded bodies, in particular pellets, containing one or more plant extracts, and the pharmaceutical or cosmetic use of such pellets

Country Status (10)

Country Link
EP (1) EP0620727B1 (en)
JP (1) JPH07502735A (en)
AT (1) ATE151631T1 (en)
AU (1) AU679905B2 (en)
CA (1) CA2128242C (en)
DE (1) DE59306197D1 (en)
DK (1) DK0620727T3 (en)
ES (1) ES2102637T3 (en)
GR (1) GR3024062T3 (en)
WO (1) WO1993013754A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2133633T3 (en) 1992-01-17 1999-09-16 Alfatec Pharma Gmbh PROCEDURE FOR THE PRODUCTION OF POWDERS, GRANULATES OR PELETS CONTAINING AN ACTIVE SUBSTANCE, WITH A STRUCTURE BASED ON HYDROPHILIC MACROMOLECULES, AND THEIR USE.
DE19603019C2 (en) * 1996-01-17 1998-10-15 Lancaster Group Gmbh Cosmetic skin cleanser based on natural ingredients
IL131317A (en) * 1999-08-09 2006-08-01 Cts Chemical Ind Ltd Binder for pharmaceutical compositions
JP2003160440A (en) * 2001-11-26 2003-06-03 Mikimoto Pharmaceut Co Ltd Nacreous layer powder
EP1551373B1 (en) * 2002-10-16 2014-11-12 MedSkin Solutions Dr. Suwelack AG Use of molded bodies for external application
EP1613171B1 (en) 2003-04-11 2015-09-09 Cargill, Incorporated Pellet systems for preparing beverages
US20110293813A1 (en) * 2008-07-18 2011-12-01 Cargill, Incorporated Frozen pellets made with juice
EP4230187A1 (en) * 2022-02-21 2023-08-23 Biofactoria Naturae Et Salus Sa Single-dose cosmetic product and process of manufacturing thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE454386C (en) * 1924-05-27 1928-01-06 Chemische Produkte Vormals H S Process for the production of pharmaceutical and dietetic preparations in spherical form
GB242323A (en) * 1924-07-04 1925-11-04 Firm Knoll & Co Chem Fab An improved method of manufacturing medicinal jujubes
GB887901A (en) * 1960-04-13 1900-01-01
FR1397583A (en) * 1964-05-04 1965-04-30 Hoffmann La Roche Process for the preparation of compositions containing substances sensitive to oxidation
BE770604A (en) * 1971-07-28 1971-12-01 Hoffmann La Roche High potency vitamin e powders
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution

Also Published As

Publication number Publication date
AU3343193A (en) 1993-08-03
WO1993013754A1 (en) 1993-07-22
ES2102637T3 (en) 1997-08-01
JPH07502735A (en) 1995-03-23
DK0620727T3 (en) 1997-05-26
EP0620727B1 (en) 1997-04-16
DE59306197D1 (en) 1997-05-22
EP0620727A1 (en) 1994-10-26
ATE151631T1 (en) 1997-05-15
AU679905B2 (en) 1997-07-17
CA2128242C (en) 1998-09-22
GR3024062T3 (en) 1997-10-31

Similar Documents

Publication Publication Date Title
Bassi Electron microscopy of rat liver after carbon tetrachloride poisoning
CA2159353C (en) Microcapsules with walls made of cross-linked plant polyphenols, and compositions containing same
Baggiolini et al. The polymorphonuclear leukocyte
CA2128242A1 (en) Moulded Bodies, in Particular Pellets, Containing One or More Plant Extracts, and the Pharmaceutical or Cosmetic Use of Such Pellets
MX9206952A (en) REDISPERSIBLE DISPERSION POWDER FROM A N-VINYLPYROLIDONE VINYL ACETATE COPOLYMERIZED ITS PREPARATION AND USE
CA2190882A1 (en) The production of active substance compositions in the form of a solid solution of the active substance in a polymer matrix, and active substance compositions produced by this process
GR3026367T3 (en) Small particle drug compositions
HUT61031A (en) Process for producing chemically modified, stable haemoglobin substituting for non-immunogehic red blood cell, and pharmaceutical compositions comprising same as active ingredient
KR910018406A (en) Polypeptides
MY112231A (en) Pharmaceutical and other dosage forms
CA2016824A1 (en) Water-soluble copolymers, a process for their preparation and their use as fluidizers in suspensions of solid matters
NO874203D0 (en) SOFTWARE PRODUCT AND PROCEDURE IN ITS MANUFACTURING.
AU7448394A (en) Preparation of diagnostic agents
WO1990003123A3 (en) Hydrophobic protein microparticles and preparation thereof
CA2026915A1 (en) Stem cell factor
JPS6463505A (en) Cosmetics
DE58907102D1 (en) Process for the production of finely divided, gel-like, water-swellable copolymers.
CA2152386A1 (en) Fatty ingredient
FI20075338A (en) No looping changes to gb350 / 220
Jeng et al. Purification and characterization of reversible sperm motility inhibitors from porcine seminal plasma
CA2034639A1 (en) Encapsulated products
ES8607984A1 (en) Pharmaceutical composition
CA2032253A1 (en) 5-lipoxygenase activating protein
Landemore et al. Kurloff cell proteoglycans: evidence for de novo synthesis of chondroitin sulphate proteoglycans by purified Kurloff cells
EP1001744B1 (en) MICROPARTICLES BASED ON HYBRID POLYMERIC MATERIALS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE MOLECULES, A PROCESS FOR PREPARING THE SAME AND THEIR USES FOR $i(IN VIVO) AND $i(IN VITRO) THERAPY, PROPHYLAXIS AND DIAGNOSTICS

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed