GB887901A - - Google Patents

Info

Publication number
GB887901A
GB887901A GB887901DA GB887901A GB 887901 A GB887901 A GB 887901A GB 887901D A GB887901D A GB 887901DA GB 887901 A GB887901 A GB 887901A
Authority
GB
United Kingdom
Prior art keywords
vitamin
gelatine
droplets
solutions
products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of GB887901A publication Critical patent/GB887901A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A23L29/281—Proteins, e.g. gelatin or collagen
    • A23L29/284—Gelatin; Collagen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0091—Preparation of aerogels, e.g. xerogels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

887,901. Vitamin compositions. HOFFMANN-LA ROCHE & CO. A.G., F. April 11, 1960 [April 17, 1959], No. 12781/60. Class 81 (1). [Also in Groups III, IV (a) and IV (b)] Dry particulate products are obtained from gellable colloidal aqueous solutions, e.g. solutions of pectin, agar, tragacanth, alginates and gelatine, which may, if desired, contain additional materials such as vitamins, flavouring agents, colouring compositions and growth stimulants, by subdividing the solutions into fine droplets in a gaseous medium having a temperature at least 10‹ C. below the melting-point of the resulting gel, keeping the droplets separated for a time sufficient for gelling to begin and then drying the particles, which have gelled sufficiently and lost enough water to avoid agglomeration, to cause them to set permanently in gel form. Sub-division may be effected by spraying, atomizing, releasing through fine openings or by releasing a thin layer on a rotating plate, and the droplets may be gelled by falling through a still gas or through gas flowing in countercurrent to the falling droplets. Preferred duration of fall is at least 15 seconds over distances not less than 4 metres. The aqueous colloidal solutions may include a minor proportion, e.g. 10-30%, of an organic solvent, such as a lower aliphatic alcohol, e.g. ethanol, and may also include plasticizers, anti-oxidants, emulsifiers and preservatives, a number of each of which are specified. Air, nitrogen and carbon dioxide are specified gaseous media, the gas temperature being held at 10-20 C. below the melting-point of the resulting gel. Relative humidity in the gas should not exceed 30%. The drying of the gelled particles is effected preferably between 10‹ and 50‹ C., and the resistance of particles to water may be improved by treatment with a hardening agent, e.g. formaldehyde. Examples are given of the manufacture of particulate products from aqueous solutions containing: (1) gelatine, Vitamin A acetate, disodium ethylenediamine tetracetate, sugar, and butylated hydroxytoluene, with or without polyoxyethylene sorbitan mono-oleate; (2) gelatine, Vitamin A palmitate, invert sugar, butylated hydroxyanisole, propyl gallate, propyl phydroxybenzoate and #-phenoxyethyldimethyldodecyl ammonium bromide; and (3) gelatine, DL-α-tocopherol acetate, invert sugar, and #- phenoxyethyldimethyldodecyl ammonium bromide. Reference is made also to the preparation of carotenoid-containing products, e.g. products containing carotene, #-apo-8<SP>1</SP>-carotenal (C30), canthaxanthin, zeaxanthin, and lycopene, and products containing Vitamin B 1 , Vitamin C or panthenol.
GB887901D 1960-04-13 Expired GB887901A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR824210A FR1259081A (en) 1960-04-13 1960-04-13 Process for the preparation of a product with dry particles, in particular from a colloidal solution

Publications (1)

Publication Number Publication Date
GB887901A true GB887901A (en) 1900-01-01

Family

ID=8729217

Family Applications (1)

Application Number Title Priority Date Filing Date
GB887901D Expired GB887901A (en) 1960-04-13

Country Status (3)

Country Link
FR (1) FR1259081A (en)
GB (1) GB887901A (en)
MY (1) MY6200070A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5662840A (en) * 1994-06-10 1997-09-02 Fmc Corporation Process for making gel microbeads
US5876754A (en) * 1992-01-17 1999-03-02 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
EP1172083A3 (en) * 2000-06-30 2002-09-11 Kao Corporation Hydrogel matrix particles comprising a dispersed lipophilic component, process of preparation and skin cosmetic composition containing hydrogel particles
WO2003091315A1 (en) * 2002-04-25 2003-11-06 Amersham Biosciences Ab Manufacture of polysaccharide beads

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0266909A1 (en) * 1986-10-06 1988-05-11 Midwest Research Institute Method of micro-encapsulating chemicals
EP0615445B1 (en) * 1991-12-05 1996-05-15 ALFATEC-PHARMA GmbH Pharmaceutically applicable nanosol and process for preparing the same
US5578307A (en) * 1992-01-17 1996-11-26 Alfatec-Pharma Gmbh Shaped articles containing plant extract(s), in particular pellets, and their pharmaceutical or cosmetic use
EP0621775B1 (en) * 1992-01-17 1997-08-06 ALFATEC-PHARMA GmbH Pellets containing peptide drugs, their manufacture and use
WO1993013754A1 (en) * 1992-01-17 1993-07-22 Alfatec-Pharma Gmbh Moulded bodies, in particular pellets, containing one or more plant extracts, and the pharmaceutical or cosmetic use of such pellets
EP0621777B1 (en) * 1992-01-17 1996-09-11 ALFATEC-PHARMA GmbH Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
DE4221880A1 (en) * 1992-07-03 1994-01-05 Alfatec Pharma Gmbh Solid and liquid solutions of poorly water-soluble drugs

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876754A (en) * 1992-01-17 1999-03-02 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
US6103269A (en) * 1992-01-17 2000-08-15 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
US5662840A (en) * 1994-06-10 1997-09-02 Fmc Corporation Process for making gel microbeads
EP1172083A3 (en) * 2000-06-30 2002-09-11 Kao Corporation Hydrogel matrix particles comprising a dispersed lipophilic component, process of preparation and skin cosmetic composition containing hydrogel particles
US8017046B2 (en) 2000-06-30 2011-09-13 Kao Corporation Skin cosmetic composition
WO2003091315A1 (en) * 2002-04-25 2003-11-06 Amersham Biosciences Ab Manufacture of polysaccharide beads
US7341682B2 (en) 2002-04-25 2008-03-11 Ge Healthcare Bio-Sciences Ab Manufacture of polysaccharide beads

Also Published As

Publication number Publication date
MY6200070A (en) 1962-12-31
FR1259081A (en) 1961-04-21

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