CA2122138A1 - Methode d'enrichissement de cellules foetales du sang maternel - Google Patents

Methode d'enrichissement de cellules foetales du sang maternel

Info

Publication number
CA2122138A1
CA2122138A1 CA 2122138 CA2122138A CA2122138A1 CA 2122138 A1 CA2122138 A1 CA 2122138A1 CA 2122138 CA2122138 CA 2122138 CA 2122138 A CA2122138 A CA 2122138A CA 2122138 A1 CA2122138 A1 CA 2122138A1
Authority
CA
Canada
Prior art keywords
cells
blood
fetal
ligand
maternal blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2122138
Other languages
English (en)
Inventor
Sheryl Williams
Ronald J. Berenson
Shelly Heimfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CellPro Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2122138A1 publication Critical patent/CA2122138A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0641—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/14—Erythropoietin [EPO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA 2122138 1991-10-23 1992-10-22 Methode d'enrichissement de cellules foetales du sang maternel Abandoned CA2122138A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78214891A 1991-10-23 1991-10-23
US782,148 1991-10-23

Publications (1)

Publication Number Publication Date
CA2122138A1 true CA2122138A1 (fr) 1993-04-29

Family

ID=25125136

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2122138 Abandoned CA2122138A1 (fr) 1991-10-23 1992-10-22 Methode d'enrichissement de cellules foetales du sang maternel

Country Status (4)

Country Link
EP (1) EP0610359A1 (fr)
JP (1) JPH07500499A (fr)
CA (1) CA2122138A1 (fr)
WO (1) WO1993008269A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994025873A1 (fr) * 1993-04-23 1994-11-10 Cellpro, Incorporated Procedes d'enrichissement de cellules souches f×tales provenant du sang maternel
US5580724A (en) * 1994-03-25 1996-12-03 Board Of Regents, The University Of Texas System Differential expansion of fetal stem cells in maternal circulation for use in prenatal genetic analysis
WO1995026417A1 (fr) * 1994-03-29 1995-10-05 Genzyme Corporation Culture et isolation de cellules f×tales a partir de sang peripherique maternel
US5648223A (en) * 1994-08-31 1997-07-15 Activated Cell Therapy, Inc. Methods for enriching breast tumor cells
US5840502A (en) * 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US5646004A (en) * 1994-08-31 1997-07-08 Activated Cell Therapy, Inc. Methods for enriching fetal cells from maternal body fluids
US5663051A (en) * 1994-08-31 1997-09-02 Activated Cell Therapy, Inc. Separation apparatus and method
GB0009179D0 (en) * 2000-04-13 2000-05-31 Imp College Innovations Ltd Non-invasive prenatal diagnosis
JP2010029178A (ja) * 2008-07-01 2010-02-12 Osaka Univ 細胞ピッキングシステム、スクリーニング方法および哺乳類細胞を取得する方法
CN106119189B (zh) * 2016-07-11 2020-04-10 山东亚大药业有限公司 胎儿有核红细胞的分离纯化方法及试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3044015C2 (de) * 1980-11-22 1984-03-29 Uwe Dr.med. 5223 Harscheid Claussen Verfahren und Einrichtung zur Präparation von in Teilung vorliegenden Zellen für die Chromosomenanalyse
WO1990006509A1 (fr) * 1988-12-06 1990-06-14 Flinders Technologies Pty. Ltd. Procede servant a isoler des cellules f×tales du sang maternel en vue d'un diagnostic prenatal
DE69032112T2 (de) * 1989-08-03 1998-07-09 Univ California Verfahren zur Isolierung von fetalen Zytotrophoblastzellen
JPH05501612A (ja) * 1989-11-13 1993-03-25 チルドレンズ・メデイカル・センター・コーポレーシヨン 胎児ｄｎａ単離および検出のための非侵入性方法

Also Published As

Publication number Publication date
WO1993008269A1 (fr) 1993-04-29
EP0610359A1 (fr) 1994-08-17
JPH07500499A (ja) 1995-01-19

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead