CA2117889A1 - Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline - Google Patents

Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline

Info

Publication number
CA2117889A1
CA2117889A1 CA002117889A CA2117889A CA2117889A1 CA 2117889 A1 CA2117889 A1 CA 2117889A1 CA 002117889 A CA002117889 A CA 002117889A CA 2117889 A CA2117889 A CA 2117889A CA 2117889 A1 CA2117889 A1 CA 2117889A1
Authority
CA
Canada
Prior art keywords
neurotrophin
neurite growth
antibody
myelin
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002117889A
Other languages
English (en)
Inventor
Martin E. Schwab
Lisa Schnell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zurich Canton of Erziehungsdirektion
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2117889A1 publication Critical patent/CA2117889A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002117889A 1993-02-11 1994-02-08 Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline Abandoned CA2117889A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1635493A 1993-02-11 1993-02-11
US08/016,354 1993-02-11
PCT/IB1994/000011 WO1994017831A1 (fr) 1993-02-11 1994-02-08 Association de la neurotrophine et d'un anticorps contre la proteine inhibitrice de la croissance de neurites associee a la myeline stimulant la regeneration du systeme nerveux central

Publications (1)

Publication Number Publication Date
CA2117889A1 true CA2117889A1 (fr) 1994-08-18

Family

ID=21776697

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002117889A Abandoned CA2117889A1 (fr) 1993-02-11 1994-02-08 Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline

Country Status (7)

Country Link
EP (1) EP0634939A1 (fr)
JP (1) JPH07509002A (fr)
AU (1) AU5891394A (fr)
CA (1) CA2117889A1 (fr)
IL (1) IL108600A0 (fr)
WO (1) WO1994017831A1 (fr)
ZA (1) ZA94887B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6576441B1 (en) 1995-12-06 2003-06-10 Sumitomo Pharmaceuticals Company, Limited Semaphorin Z and gene encoding the same
WO1998011216A1 (fr) 1996-09-11 1998-03-19 Sumitomo Pharmaceuticals Company, Limited Nouveau gene de semaphorine: semaphorine y
US6902730B1 (en) 1996-10-09 2005-06-07 Sumitomo Pharmaceuticals Company, Limited Semaphorin gene: Semaphorin W
CA2190418A1 (fr) * 1996-11-15 1998-05-15 Zhi-Cheng Xiao Systeme regulateur pour la croissance des neurones et des tumeurs neuronales; anticorps utilises a cette fin et applications
AU4964097A (en) 1996-11-15 1998-06-10 Sumitomo Pharmaceuticals Company, Limited Novel semaphorin genes (i)
EP0878480A1 (fr) * 1997-05-14 1998-11-18 H.W. Prof. Dr. Müller Procédé pour ameliorer la régénération nerveuse
SE9901428D0 (sv) * 1999-04-21 1999-04-21 Karolinska Innovations Ab Amphibodies
AU784349C (en) 2000-01-12 2006-09-28 Yale University Nogo receptor-mediated blockade of axonal growth
NZ525422A (en) 2000-10-06 2006-09-29 Biogen Idec Inc Isolated polynucleotides comprising a nucleic acid which encodes a polypeptide which modulates axonal growth in CNS neurons
CA2549000A1 (fr) * 2003-12-16 2005-06-30 Children's Medical Center Corporation Procede de traitement de troubles neurologiques
US8912144B2 (en) 2003-12-16 2014-12-16 Children's Medical Center Corporation Method for treating stroke via administration of NEP1-40 and inosine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100196540B1 (ko) * 1988-11-04 1999-06-15 마틴 이. 샤브 축색성장 조절인자
GR1000980B (el) * 1989-08-30 1993-03-31 Max Planck Gesellschaft Νευροτροφινη-3,ενας νεος neυροτροφικος παραγοντας που σχετιζεται με τον παραγοντα αναπτυξης νευρων και τον νευροτροφικο παραγοντα που προερχεται απο τον εγκεφαλο.
WO1993000427A2 (fr) * 1991-06-24 1993-01-07 Erziehungsdirektion Of The Canton Zurich Facteurs regulateurs de la croissance des neurites
JP2008027291A (ja) * 2006-07-24 2008-02-07 Hitachi Ltd ストレージ装置及びデータ保護方法

Also Published As

Publication number Publication date
ZA94887B (en) 1994-08-23
JPH07509002A (ja) 1995-10-05
IL108600A0 (en) 1994-05-30
EP0634939A1 (fr) 1995-01-25
WO1994017831A1 (fr) 1994-08-18
AU5891394A (en) 1994-08-29

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 19980209