CA2117889A1 - Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline - Google Patents
Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myelineInfo
- Publication number
- CA2117889A1 CA2117889A1 CA002117889A CA2117889A CA2117889A1 CA 2117889 A1 CA2117889 A1 CA 2117889A1 CA 002117889 A CA002117889 A CA 002117889A CA 2117889 A CA2117889 A CA 2117889A CA 2117889 A1 CA2117889 A1 CA 2117889A1
- Authority
- CA
- Canada
- Prior art keywords
- neurotrophin
- neurite growth
- antibody
- myelin
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1635493A | 1993-02-11 | 1993-02-11 | |
US08/016,354 | 1993-02-11 | ||
PCT/IB1994/000011 WO1994017831A1 (fr) | 1993-02-11 | 1994-02-08 | Association de la neurotrophine et d'un anticorps contre la proteine inhibitrice de la croissance de neurites associee a la myeline stimulant la regeneration du systeme nerveux central |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2117889A1 true CA2117889A1 (fr) | 1994-08-18 |
Family
ID=21776697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002117889A Abandoned CA2117889A1 (fr) | 1993-02-11 | 1994-02-08 | Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0634939A1 (fr) |
JP (1) | JPH07509002A (fr) |
AU (1) | AU5891394A (fr) |
CA (1) | CA2117889A1 (fr) |
IL (1) | IL108600A0 (fr) |
WO (1) | WO1994017831A1 (fr) |
ZA (1) | ZA94887B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6576441B1 (en) | 1995-12-06 | 2003-06-10 | Sumitomo Pharmaceuticals Company, Limited | Semaphorin Z and gene encoding the same |
WO1998011216A1 (fr) | 1996-09-11 | 1998-03-19 | Sumitomo Pharmaceuticals Company, Limited | Nouveau gene de semaphorine: semaphorine y |
US6902730B1 (en) | 1996-10-09 | 2005-06-07 | Sumitomo Pharmaceuticals Company, Limited | Semaphorin gene: Semaphorin W |
CA2190418A1 (fr) * | 1996-11-15 | 1998-05-15 | Zhi-Cheng Xiao | Systeme regulateur pour la croissance des neurones et des tumeurs neuronales; anticorps utilises a cette fin et applications |
AU4964097A (en) | 1996-11-15 | 1998-06-10 | Sumitomo Pharmaceuticals Company, Limited | Novel semaphorin genes (i) |
EP0878480A1 (fr) * | 1997-05-14 | 1998-11-18 | H.W. Prof. Dr. Müller | Procédé pour ameliorer la régénération nerveuse |
SE9901428D0 (sv) * | 1999-04-21 | 1999-04-21 | Karolinska Innovations Ab | Amphibodies |
AU784349C (en) | 2000-01-12 | 2006-09-28 | Yale University | Nogo receptor-mediated blockade of axonal growth |
NZ525422A (en) | 2000-10-06 | 2006-09-29 | Biogen Idec Inc | Isolated polynucleotides comprising a nucleic acid which encodes a polypeptide which modulates axonal growth in CNS neurons |
CA2549000A1 (fr) * | 2003-12-16 | 2005-06-30 | Children's Medical Center Corporation | Procede de traitement de troubles neurologiques |
US8912144B2 (en) | 2003-12-16 | 2014-12-16 | Children's Medical Center Corporation | Method for treating stroke via administration of NEP1-40 and inosine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100196540B1 (ko) * | 1988-11-04 | 1999-06-15 | 마틴 이. 샤브 | 축색성장 조절인자 |
GR1000980B (el) * | 1989-08-30 | 1993-03-31 | Max Planck Gesellschaft | Νευροτροφινη-3,ενας νεος neυροτροφικος παραγοντας που σχετιζεται με τον παραγοντα αναπτυξης νευρων και τον νευροτροφικο παραγοντα που προερχεται απο τον εγκεφαλο. |
WO1993000427A2 (fr) * | 1991-06-24 | 1993-01-07 | Erziehungsdirektion Of The Canton Zurich | Facteurs regulateurs de la croissance des neurites |
JP2008027291A (ja) * | 2006-07-24 | 2008-02-07 | Hitachi Ltd | ストレージ装置及びデータ保護方法 |
-
1994
- 1994-02-08 AU AU58913/94A patent/AU5891394A/en not_active Abandoned
- 1994-02-08 EP EP94905206A patent/EP0634939A1/fr not_active Withdrawn
- 1994-02-08 CA CA002117889A patent/CA2117889A1/fr not_active Abandoned
- 1994-02-08 WO PCT/IB1994/000011 patent/WO1994017831A1/fr not_active Application Discontinuation
- 1994-02-08 JP JP6517851A patent/JPH07509002A/ja active Pending
- 1994-02-09 IL IL10860094A patent/IL108600A0/xx unknown
- 1994-02-09 ZA ZA94887A patent/ZA94887B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA94887B (en) | 1994-08-23 |
JPH07509002A (ja) | 1995-10-05 |
IL108600A0 (en) | 1994-05-30 |
EP0634939A1 (fr) | 1995-01-25 |
WO1994017831A1 (fr) | 1994-08-18 |
AU5891394A (en) | 1994-08-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR0175657B1 (ko) | 에리트로포이에틴 펩타이드 및 이에 대한 항체 | |
RU2128226C1 (ru) | Выделенный фрагмент днк, способ получения рекомбинантного белка с нейротропной активностью, белок nt-3 и фармацевтическая композиция | |
US6291247B1 (en) | Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity | |
AU667996B2 (en) | Modified ciliary neurotrophic factors | |
CA2040437C (fr) | Neurotrophine-3, nouveau facteur neurotrophique lie au facteur de croissance du tissu nerveux et au facteur neurotrophique derive du cerveau | |
EP0527806B1 (fr) | Epithelines: de nouvelles proteines modulatrices de la croissance riches en cysteine | |
EP0396719B1 (fr) | Facteurs de regulation de la croissance des neurites | |
SK1499A3 (en) | Analogs of cationic proteins | |
JP2006087434A (ja) | 新規な神経栄養因子 | |
CA2129423A1 (fr) | Recepteur de facteur de croissance hepatique | |
US20140179614A1 (en) | Metallothionein-Derived Peptide Fragments | |
JPH10501138A (ja) | 汎親和性神経栄養因子 | |
US5767240A (en) | Activity-dependent neurotrophic factor | |
WO1998022499A9 (fr) | Systeme de regulation de la croissance tumorale neuronale et neurale, anticorps destines a cet effet et utilisations de ceux-ci | |
WO1998022499A2 (fr) | Systeme de regulation de la croissance tumorale neuronale et neurale, anticorps destines a cet effet et utilisations de ceux-ci | |
CA2117889A1 (fr) | Methode favorisant la regeneration du systeme nerveux central qui combine une neurotrophine et un anticorps dirige contre une proteine inhibant la croissance des neurites et associee a la myeline | |
JPH07506488A (ja) | neuレセプターの組換え刺激因子 | |
BRPI0614419A2 (pt) | peptìdeos derivados de gdnf | |
EP0966533B1 (fr) | Facteur neurotrophique iii dependant de l'activite (adnf iii) | |
WO1994017831A9 (fr) | Association de la neurotrophine et d'un anticorps contre la proteine inhibitrice de la croissance de neurites associee a la myeline stimulant la regeneration du systeme nerveux central | |
EP0377855B1 (fr) | Facteur de croissance des cellules endothéliales | |
JPH08500246A (ja) | 細胞増殖の阻害剤,その調製および用途 | |
US5504197A (en) | DNA encoding neurotrophic growth factors | |
Sottile et al. | Assembly of fibronectin molecules with mutations or deletions of the carboxyl-terminal type I modules | |
EP2121740A2 (fr) | Peptides derives de la famille des proteines s-100 favorisant la survie neuritogene et neuronale |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 19980209 |