CA2096575C - Compositions pharmaceutiques contenant de la dimethicone - Google Patents

Compositions pharmaceutiques contenant de la dimethicone Download PDF

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Publication number
CA2096575C
CA2096575C CA002096575A CA2096575A CA2096575C CA 2096575 C CA2096575 C CA 2096575C CA 002096575 A CA002096575 A CA 002096575A CA 2096575 A CA2096575 A CA 2096575A CA 2096575 C CA2096575 C CA 2096575C
Authority
CA
Canada
Prior art keywords
loperamide
simethicone
pharmaceutical
dosage form
oral dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002096575A
Other languages
English (en)
Other versions
CA2096575A1 (fr
Inventor
Charles A. Stevens
Michael R. Hoy
Edward J. Roche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26715151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2096575(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Publication of CA2096575A1 publication Critical patent/CA2096575A1/fr
Application granted granted Critical
Publication of CA2096575C publication Critical patent/CA2096575C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002096575A 1992-05-21 1993-05-19 Compositions pharmaceutiques contenant de la dimethicone Expired - Lifetime CA2096575C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88720792A 1992-05-21 1992-05-21
US07/887,207 1992-05-21
US3839793A 1993-03-29 1993-03-29
US08/38397 1993-03-29

Publications (2)

Publication Number Publication Date
CA2096575A1 CA2096575A1 (fr) 1993-11-22
CA2096575C true CA2096575C (fr) 2003-05-13

Family

ID=26715151

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002096575A Expired - Lifetime CA2096575C (fr) 1992-05-21 1993-05-19 Compositions pharmaceutiques contenant de la dimethicone

Country Status (7)

Country Link
US (4) US5679376A (fr)
EP (1) EP0571217B1 (fr)
BR (1) BR1100507A (fr)
CA (1) CA2096575C (fr)
DE (1) DE69315257T2 (fr)
ES (1) ES2112387T3 (fr)
GR (1) GR1002332B (fr)

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WO1996004128A1 (fr) * 1994-08-03 1996-02-15 Voss Gunter M Procede de fabrication de comprimes enrobes
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
US5919481A (en) * 1996-06-28 1999-07-06 Ncneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form
US6537525B1 (en) * 1997-01-29 2003-03-25 Douglas H. West Medicated chewing-gum
US6103260A (en) * 1997-07-17 2000-08-15 Mcneil-Ppc, Inc. Simethicone/anhydrous calcium phosphate compositions
US6800329B2 (en) * 1999-02-12 2004-10-05 Lts Lohmann Therapie-Systeme Ag Method for producing film-type dosage
US6270807B1 (en) 1999-03-02 2001-08-07 L. Perrigo Company Taste-masked pharmaceutical composition
US6100245A (en) * 1999-09-07 2000-08-08 Mcneil-Ppc, Inc. Use of simethicone to treat ulcerative colitis
CN1288730A (zh) * 1999-09-07 2001-03-28 麦克内尔-Ppc股份有限公司 轻泻组合物
EP1242057A2 (fr) * 1999-11-02 2002-09-25 DepoMed, Inc. Declenchement pharmacologique du mode par ingestion pour une administration amelioree de medicaments dans l'estomac
DK1294372T3 (da) * 2000-06-23 2005-09-19 Bioprojet Soc Civ Törpulverformulering der omdanner racecadotril
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US6669271B2 (en) * 2001-06-22 2003-12-30 East Manufacturing Corporation Smooth side body structure and method
BR0212950A (pt) 2001-09-28 2004-10-26 Mcneil Ppc Inc Formas de dosagens compósitas tendo uma porção inserida
US7101573B2 (en) * 2001-09-28 2006-09-05 Mcneil-Pcc, Inc. Simethicone solid oral dosage form
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US7341742B2 (en) * 2002-09-30 2008-03-11 L. Perrigo Company Simethicone containing tablet composition and method
US7378081B2 (en) * 2003-01-29 2008-05-27 Vincon Research Enterprises, Llc Composition and method for direct visualization of the human appendix
US20050180920A1 (en) * 2003-01-29 2005-08-18 Vincenzo Giuliano Oral contrast media composition for computerized axial tomographic examinations and method
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7096533B2 (en) * 2004-06-12 2006-08-29 Kruegar International, Inc. Locking roller for an article of furniture
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
EP1992345A4 (fr) * 2006-03-09 2010-07-28 Espinoza Abdala Leopoldo De Je Combinaison synergique d'inhibiteurs des récepteurs h2, de silicone inerte et d'un complexe d'aluminate d'hydroxymagnésium
US7976872B2 (en) * 2006-07-24 2011-07-12 L. Perrigo Company Method for distributing a pharmaceutically active compound in an excipient
US7754041B2 (en) * 2006-07-31 2010-07-13 3M Innovative Properties Company Pleated filter with bimodal monolayer monocomponent media
US7662373B2 (en) * 2006-09-18 2010-02-16 Thompson Ronald J Method and composition of a medicament to decrease the adverse events of Olistat, an oral lipase inhibitor
WO2008056200A1 (fr) * 2006-11-10 2008-05-15 Ranbaxy Laboratories Limited Compositions pharmaceutiques orales de siméthicone
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
CA2860231A1 (fr) 2011-12-28 2013-07-04 Pozen Inc. Compositions et procedes d'administration d'omeprazole plus acide acetylsalicylique ameliores
MA41620A (fr) 2015-05-14 2018-01-09 Abdi Ibrahim Ilac Sanayi Ve Ticaret A S Composition pharmaceutique comprenant de la siméthicone et de l'otilonium
WO2016200345A1 (fr) 2015-06-12 2016-12-15 Santa Farma İlaç Sanayi̇ A. Ş. Composition pharmaceutique orale comprenant du bromure d'otilonium et de la siméthicone présentant une certaine densité en vrac et des caractéristiques de dissolution améliorées
CN108712900A (zh) 2015-12-19 2018-10-26 第时间美国泛型药物有限公司 软咀嚼片剂药物制剂
US20190022013A1 (en) 2015-12-19 2019-01-24 First Time Us Generics Llc Soft-chew tablet pharmaceutical formulations
US10722472B2 (en) 2017-09-29 2020-07-28 Johnson & Johnson Consumer Inc. Solid simethicone particles and dosage form thereof
CN111867567A (zh) * 2018-02-26 2020-10-30 R·P·舍勒科技有限责任公司 二甲硅油和洛哌丁胺的乳剂的药物剂型
GR1009632B (el) * 2018-07-09 2019-10-25 Ιουλια Κλεωνος Τσετη Διατροφικο συμπληρωμα για την απο του στοματος χορηγηση συνδυασμου λακτοφερινης, ξυλογλυκανης, προανθοκυανιδινων και σιμεθικονης, χρησιμων για την προληψη λοιμωξεων του γαστρεντερικου και ουροποιητικου συστηματος
KR20240095472A (ko) * 2021-11-16 2024-06-25 존슨 앤드 존슨 컨수머 인코포레이티드 시메티콘을 함유하는 맞춤화 가능한 투여 형태
WO2023187225A1 (fr) * 2022-04-01 2023-10-05 Amplicon Ab Produits intra-buccaux alcalins

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3048526A (en) * 1958-08-04 1962-08-07 Wander Company Medicinal tablet
GB971486A (en) * 1960-04-01 1964-09-30 Rech S Pharma Et Scient Therapeutic compositions comprising aspirin and polysiloxanes
US3767794A (en) * 1969-11-21 1973-10-23 Richardson Merrell Inc Antifoam preparations and method of preparing same
NL7504704A (nl) * 1974-05-16 1975-11-18 Hoffmann La Roche Geneesmiddel.
US4127650A (en) * 1975-03-31 1978-11-28 William H. Rorer, Inc. Medicinal simethicone containing composition and its method of production
CA1139221A (fr) * 1978-10-10 1983-01-11 Vijay B. Surpuriya Anti-acide
US4198390A (en) * 1979-01-31 1980-04-15 Rider Joseph A Simethicone antacid tablet
US4316888A (en) * 1980-04-15 1982-02-23 Nelson Research & Development Co. Method and composition of reducing pain
US4428927A (en) * 1981-05-11 1984-01-31 R. P. Scherer Corporation Masticatory soft elastic gelatin capsules and method for the manufacture thereof
US4396604A (en) * 1982-05-17 1983-08-02 Norcliff Thayer, Inc. Simethicone antacid lozenge
US4639368A (en) * 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
US4857324A (en) * 1985-10-08 1989-08-15 American Home Products Corporation (Del.) Exogenously acidified antacid compositions having cytoprotective properties
EP0294933B1 (fr) * 1987-05-08 1992-03-11 Smith Kline & French Laboratories Limited Compositions pharmaceutiques
GB8710965D0 (en) * 1987-05-08 1987-06-10 Smith Kline French Lab Pharmaceutical compositions
US5275819A (en) * 1989-02-06 1994-01-04 Amer Particle Technologies Inc. Drug loaded pollen grains with an outer coating for pulsed delivery
US5073384A (en) * 1989-10-19 1991-12-17 Valentine Enterprises, Inc. Maltodextrin/defoaming composition combinate
NZ235876A (en) * 1989-11-01 1992-06-25 Mcneil Ppc Inc Pharmaceutical compositions containing effective amount of antidiarrheal composition and antiflatulent effective amount of simethicone
US5204118A (en) * 1989-11-02 1993-04-20 Mcneil-Ppc, Inc. Pharmaceutical compositions and methods for treating the symptoms of overindulgence
US5198227A (en) * 1990-01-22 1993-03-30 Mcneil-Ppc, Inc. Dual subcoated simulated capsule medicament
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5116847A (en) * 1991-01-25 1992-05-26 The Procter & Gamble Company Use of loperamide and related compounds for treatment of respiratory disease symptoms
US5229137A (en) * 1992-05-06 1993-07-20 Brigham And Women's Hospital, Inc. Methods and pharmaceutical compositions for treating episodic heartburn
US5447918A (en) * 1992-07-27 1995-09-05 Mccullough; Ricky W. Gastrointestinal anti-irritant composition comprising sucralfate and methods of use
US5288507A (en) * 1992-07-29 1994-02-22 Merck & Co., Inc. Ibuprofen antacid combinations
CA2110313C (fr) * 1992-12-01 2004-10-26 Edward John Roche Compositions pharmaceutiques contenant un compose de guanidothiazole et antiacides

Also Published As

Publication number Publication date
DE69315257T2 (de) 1998-05-14
EP0571217A2 (fr) 1993-11-24
GR1002332B (el) 1996-05-16
EP0571217B1 (fr) 1997-11-19
US5679376A (en) 1997-10-21
ES2112387T3 (es) 1998-04-01
DE69315257D1 (de) 1998-01-02
EP0571217A3 (en) 1994-06-01
US5716641A (en) 1998-02-10
US5599577A (en) 1997-02-04
US5980944A (en) 1999-11-09
GR930100197A (el) 1994-01-31
BR1100507A (pt) 2002-04-02
CA2096575A1 (fr) 1993-11-22

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Legal Events

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