CA2089569A1 - 3-aryl- ou 3-hetaryl-.beta.-carbolines; preparation et utilisation dans des agents pharmaceutiques - Google Patents

3-aryl- ou 3-hetaryl-.beta.-carbolines; preparation et utilisation dans des agents pharmaceutiques

Info

Publication number
CA2089569A1
CA2089569A1 CA002089569A CA2089569A CA2089569A1 CA 2089569 A1 CA2089569 A1 CA 2089569A1 CA 002089569 A CA002089569 A CA 002089569A CA 2089569 A CA2089569 A CA 2089569A CA 2089569 A1 CA2089569 A1 CA 2089569A1
Authority
CA
Canada
Prior art keywords
carboline
methoxymethyl
benzyloxy
alkyl
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002089569A
Other languages
English (en)
Inventor
Andreas Huth
Dieter Seidelmann
Ralph Schmiechen
Herbert Schneider
Lechoslaw Turski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2089569A1 publication Critical patent/CA2089569A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA002089569A 1991-06-15 1992-06-12 3-aryl- ou 3-hetaryl-.beta.-carbolines; preparation et utilisation dans des agents pharmaceutiques Abandoned CA2089569A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4120109A DE4120109A1 (de) 1991-06-15 1991-06-15 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DEP4120109.4 1991-06-15

Publications (1)

Publication Number Publication Date
CA2089569A1 true CA2089569A1 (fr) 1992-12-16

Family

ID=6434220

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002089569A Abandoned CA2089569A1 (fr) 1991-06-15 1992-06-12 3-aryl- ou 3-hetaryl-.beta.-carbolines; preparation et utilisation dans des agents pharmaceutiques

Country Status (6)

Country Link
EP (1) EP0543968A1 (fr)
JP (1) JPH06501956A (fr)
CA (1) CA2089569A1 (fr)
DE (1) DE4120109A1 (fr)
PT (1) PT100593A (fr)
WO (1) WO1992022549A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330175A1 (de) * 1993-08-31 1995-03-02 Schering Ag Alkoxy-substituierte beta-Carboline
EP1134221A1 (fr) * 2000-03-15 2001-09-19 Aventis Pharma Deutschland GmbH Bêta-carbolines substituées comme inhibiteurs de lkB kinase

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives
DE3540654A1 (de) * 1985-11-13 1987-05-14 Schering Ag Phenoxy-substituierte ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
IL87563A (en) * 1987-08-28 1993-08-18 Schering Ag Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE3903753A1 (de) * 1989-02-06 1990-08-23 Schering Ag Verfahren zur herstellung waessriger mischmicelloesungen
DE3943225A1 (de) * 1989-12-23 1991-06-27 Schering Ag Neue ss-carboline, verfahren zu deren herstellung und deren verwendung in arzneimitteln

Also Published As

Publication number Publication date
PT100593A (pt) 1993-08-31
DE4120109A1 (de) 1992-12-17
WO1992022549A1 (fr) 1992-12-23
EP0543968A1 (fr) 1993-06-02
JPH06501956A (ja) 1994-03-03

Similar Documents

Publication Publication Date Title
SK94096A3 (en) Tetracyclic derivatives, process of preparation, their use and pharmaceutical compositions containing them
US5254563A (en) Beta-carbolines, process for their production and their use in pharmaceutical agents
WO1991009598A1 (fr) Derives de l'azaoxindole
DK169131B1 (da) Heteroaryloxy-beta-carbolinderivater, fremgangsmåde og fremstillling heraf samt deres anvendelse til fremstilling af et lægemiddel
CA1332836C (fr) Derives 3-oxadiazole et acide .beta.-carboline-3-carboxylique, leur pro duction et leur utilisation comme medicaments
HU194242B (en) Process for production of derivatives of pirrolobenzimidasole and containing thereof medical preparatives
US5604240A (en) Pyrrolo-pyridine derivatives
CA2096138A1 (fr) Derives de .beta.-carboline, leur production et leur utilisation dans des agents pharmaceutiques
FI88160C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara isoxazolyl- -karboliner
US5348958A (en) Hetaryloxy-β-carbolines, and use as pharmaceutical agents for treating epilepsy and anxiety
CA2089569A1 (fr) 3-aryl- ou 3-hetaryl-.beta.-carbolines; preparation et utilisation dans des agents pharmaceutiques
CS248739B2 (en) Production method of the new 2-substituted derivatives of ergoline
US5543519A (en) 3-aryl or 3-hetaryl-β-carbolines, their production and use in pharmaceutical agents
US4831032A (en) Cardiotonic benzimidazoles
US3293243A (en) 8-aryl-2, 3, 6, 7-tetrahydro-1, 4-diazocin-5(4h)-ones and related compounds
CA1049017A (fr) Pyrrolo (3,4-b) pyridines et leurs methodes de preparation
US6127368A (en) Anellated β-carbolines

Legal Events

Date Code Title Description
FZDE Dead