CA2087298C - Bile acid sulfurated derivatives - Google Patents

Bile acid sulfurated derivatives Download PDF

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Publication number
CA2087298C
CA2087298C CA002087298A CA2087298A CA2087298C CA 2087298 C CA2087298 C CA 2087298C CA 002087298 A CA002087298 A CA 002087298A CA 2087298 A CA2087298 A CA 2087298A CA 2087298 C CA2087298 C CA 2087298C
Authority
CA
Canada
Prior art keywords
beta
mercapto
alpha
oic acid
cholan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002087298A
Other languages
English (en)
French (fr)
Other versions
CA2087298A1 (en
Inventor
Giangermano Giuliani
Giuliano Frigerio
Roberto Pellicciari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Giuliani SpA
Original Assignee
Giuliani SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani SpA filed Critical Giuliani SpA
Publication of CA2087298A1 publication Critical patent/CA2087298A1/en
Application granted granted Critical
Publication of CA2087298C publication Critical patent/CA2087298C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002087298A 1992-01-17 1993-01-14 Bile acid sulfurated derivatives Expired - Fee Related CA2087298C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI92A000082 1992-01-17
ITMI920082A IT1258788B (it) 1992-01-17 1992-01-17 Derivati solforati di acidi biliari

Publications (2)

Publication Number Publication Date
CA2087298A1 CA2087298A1 (en) 1993-07-18
CA2087298C true CA2087298C (en) 2003-09-09

Family

ID=11361585

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002087298A Expired - Fee Related CA2087298C (en) 1992-01-17 1993-01-14 Bile acid sulfurated derivatives

Country Status (10)

Country Link
US (1) US5321019A (esLanguage)
EP (1) EP0551844B1 (esLanguage)
JP (1) JP3490470B2 (esLanguage)
AT (1) ATE167869T1 (esLanguage)
CA (1) CA2087298C (esLanguage)
DE (2) DE69319356T2 (esLanguage)
DK (1) DK0551844T3 (esLanguage)
ES (1) ES2049703T3 (esLanguage)
GR (1) GR930300124T1 (esLanguage)
IT (1) IT1258788B (esLanguage)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN186119B (esLanguage) * 1996-07-25 2001-06-23 Lg Chemical Ltd
US20040045056A1 (en) * 1998-02-26 2004-03-04 Zhizheng Chen Transformation of Brassica
US20060260005A1 (en) * 1998-02-26 2006-11-16 Zhizhen Chen Transformation of Brassica
US7960439B1 (en) 2006-06-12 2011-06-14 Iowa State University Research Foundation, Inc. Environmentally sensitive foldable oligomers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206367B (en) * 1988-04-30 1992-10-28 Sandoz Ag Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts
GB8910364D0 (en) * 1989-05-05 1989-06-21 Nat Res Dev Anti-fungal compounds
FI106800B (fi) * 1990-12-06 2001-04-12 Hoechst Ag Menetelmä uusien terapeuttisesti käyttökelpoisten dimeeristen sappihappojohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
US5321019A (en) 1994-06-14
JP3490470B2 (ja) 2004-01-26
ITMI920082A1 (it) 1993-07-17
GR930300124T1 (en) 1993-12-30
HK1012007A1 (en) 1999-07-23
DE69319356T2 (de) 1998-11-12
DE551844T1 (de) 1993-11-25
ITMI920082A0 (it) 1992-01-17
ES2049703T1 (es) 1994-05-01
EP0551844A2 (en) 1993-07-21
IT1258788B (it) 1996-02-29
EP0551844B1 (en) 1998-07-01
DE69319356D1 (de) 1998-08-06
CA2087298A1 (en) 1993-07-18
EP0551844A3 (esLanguage) 1996-05-22
ES2049703T3 (es) 1998-09-16
ATE167869T1 (de) 1998-07-15
DK0551844T3 (da) 1999-04-12
JPH0656880A (ja) 1994-03-01

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