CA2086972A1 - Process for .beta.-galactosidase-catalyzed transglycosidation with unphysiological glycosyl donors - Google Patents

Process for .beta.-galactosidase-catalyzed transglycosidation with unphysiological glycosyl donors

Info

Publication number
CA2086972A1
CA2086972A1 CA002086972A CA2086972A CA2086972A1 CA 2086972 A1 CA2086972 A1 CA 2086972A1 CA 002086972 A CA002086972 A CA 002086972A CA 2086972 A CA2086972 A CA 2086972A CA 2086972 A1 CA2086972 A1 CA 2086972A1
Authority
CA
Canada
Prior art keywords
carbon atoms
beta
employed
group
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002086972A
Other languages
English (en)
French (fr)
Inventor
Wolfgang Holla
Gunther Becker
Wilhelm Stahl
Manfred Schudok
Joachim Thiem
Bernd Sauerbrei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2086972A1 publication Critical patent/CA2086972A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
CA002086972A 1992-01-09 1993-01-08 Process for .beta.-galactosidase-catalyzed transglycosidation with unphysiological glycosyl donors Abandoned CA2086972A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4200345.8 1992-01-09
DE4200345 1992-01-09

Publications (1)

Publication Number Publication Date
CA2086972A1 true CA2086972A1 (en) 1993-07-10

Family

ID=6449250

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002086972A Abandoned CA2086972A1 (en) 1992-01-09 1993-01-08 Process for .beta.-galactosidase-catalyzed transglycosidation with unphysiological glycosyl donors

Country Status (4)

Country Link
EP (1) EP0551107A2 (enExample)
JP (1) JPH0638785A (enExample)
AU (1) AU3109993A (enExample)
CA (1) CA2086972A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0084949A3 (en) * 1982-01-21 1986-02-19 British United Shoe Machinery Limited Method of determining an operating path of a tool
SE9304316D0 (sv) * 1993-12-24 1993-12-24 Kurt Nilsson Aminosyra-konjugat
AU3264195A (en) * 1994-09-06 1996-03-27 Bioflexin Ab Amino acid conjugate
US5876981A (en) * 1996-10-17 1999-03-02 The Scripps Research Institute Transglycosylation reactions employing β-galactosidase
DE19802748A1 (de) * 1998-01-26 1999-07-29 Chemtec Leuna Ges Fuer Chemie Verfahren zur enzymatischen Synthese von Glycoaminosäurederivaten
JP4434635B2 (ja) 2003-06-12 2010-03-17 本田技研工業株式会社 自動二輪車におけるキーシリンダの配置構造

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE451849B (sv) * 1985-12-11 1987-11-02 Svenska Sockerfabriks Ab Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter
FR2640997A1 (en) * 1988-12-22 1990-06-29 Ajinomoto Kk Process for the manufacture of a galactose transfer product.
DE4013077A1 (de) * 1990-04-25 1991-10-31 Hoechst Ag Verfahren zur glycosidasekatalysierten synthese von glycokonjugaten

Also Published As

Publication number Publication date
EP0551107A2 (de) 1993-07-14
EP0551107A3 (enExample) 1994-08-31
AU3109993A (en) 1993-07-15
JPH0638785A (ja) 1994-02-15

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Legal Events

Date Code Title Description
FZDE Dead