CA2085364A1 - Metal-radionuclide complex comprising isonitrile ligands - Google Patents

Metal-radionuclide complex comprising isonitrile ligands

Info

Publication number
CA2085364A1
CA2085364A1 CA002085364A CA2085364A CA2085364A1 CA 2085364 A1 CA2085364 A1 CA 2085364A1 CA 002085364 A CA002085364 A CA 002085364A CA 2085364 A CA2085364 A CA 2085364A CA 2085364 A1 CA2085364 A1 CA 2085364A1
Authority
CA
Canada
Prior art keywords
metal
complex
radionuclide
kit
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002085364A
Other languages
English (en)
French (fr)
Inventor
Alfons M. Verbruggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2085364A1 publication Critical patent/CA2085364A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002085364A 1990-06-18 1991-06-14 Metal-radionuclide complex comprising isonitrile ligands Abandoned CA2085364A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL90201569.2 1990-06-18
EP90201569 1990-06-18

Publications (1)

Publication Number Publication Date
CA2085364A1 true CA2085364A1 (en) 1991-12-19

Family

ID=8205034

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002085364A Abandoned CA2085364A1 (en) 1990-06-18 1991-06-14 Metal-radionuclide complex comprising isonitrile ligands

Country Status (5)

Country Link
EP (1) EP0548245A1 (OSRAM)
JP (1) JPH05508162A (OSRAM)
AU (1) AU8542591A (OSRAM)
CA (1) CA2085364A1 (OSRAM)
WO (1) WO1991019516A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
DK1286704T3 (da) * 2000-06-02 2014-09-22 Univ Texas Ethylendicystein (EC)-glucose analoge konjugater
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1305160C (en) * 1985-12-23 1992-07-14 Paul Louis Bergstein Ether isonitriles and radiolabeled complexes thereof
US4885100A (en) * 1987-09-11 1989-12-05 E. I. Du Pont De Nemours And Company Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes

Also Published As

Publication number Publication date
EP0548245A1 (en) 1993-06-30
WO1991019516A1 (en) 1991-12-26
EP0548245A4 (OSRAM) 1994-01-26
JPH05508162A (ja) 1993-11-18
AU8542591A (en) 1992-01-07

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 19941214