CA2075490A1 - 6-halo-and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents - Google Patents

6-halo-and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents

Info

Publication number
CA2075490A1
CA2075490A1 CA002075490A CA2075490A CA2075490A1 CA 2075490 A1 CA2075490 A1 CA 2075490A1 CA 002075490 A CA002075490 A CA 002075490A CA 2075490 A CA2075490 A CA 2075490A CA 2075490 A1 CA2075490 A1 CA 2075490A1
Authority
CA
Canada
Prior art keywords
compound
purine
dideoxy
beta
glycero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002075490A
Other languages
English (en)
French (fr)
Inventor
Hiroaki Mitsuya
Takuma Shirasaka
Samuel Broder
Kunichika Murakami
Hidetoshi Yoshioka
Eiji Kojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanyo Kokusaku Pulp Co Ltd
US Department of Commerce
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2075490A1 publication Critical patent/CA2075490A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002075490A 1990-02-09 1991-02-08 6-halo-and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents Abandoned CA2075490A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47740690A 1990-02-09 1990-02-09
US477,406 1990-02-09
PCT/US1991/000886 WO1991012260A1 (en) 1990-02-09 1991-02-08 6-halo- and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents

Publications (1)

Publication Number Publication Date
CA2075490A1 true CA2075490A1 (en) 1991-08-10

Family

ID=23895790

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002075490A Abandoned CA2075490A1 (en) 1990-02-09 1991-02-08 6-halo-and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents

Country Status (4)

Country Link
EP (1) EP0544668A1 (ja)
JP (1) JPH05506211A (ja)
CA (1) CA2075490A1 (ja)
WO (1) WO1991012260A1 (ja)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
WO1990006671A2 (en) * 1988-12-12 1990-06-28 Palese Peter M Methods and compositions for the prophylaxis and treatment of hepatitis b virus infections
JP2619710B2 (ja) * 1989-02-27 1997-06-11 日本製紙 株式会社 ２′，３′−ジデオキシプリンヌクレオシド類の製造方法

Also Published As

Publication number Publication date
WO1991012260A1 (en) 1991-08-22
JPH05506211A (ja) 1993-09-16
EP0544668A4 (en) 1993-03-03
EP0544668A1 (en) 1993-06-09

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead