CA2069318A1 - (n-phthalimidoalkyl)piperidines - Google Patents
(n-phthalimidoalkyl)piperidinesInfo
- Publication number
- CA2069318A1 CA2069318A1 CA002069318A CA2069318A CA2069318A1 CA 2069318 A1 CA2069318 A1 CA 2069318A1 CA 002069318 A CA002069318 A CA 002069318A CA 2069318 A CA2069318 A CA 2069318A CA 2069318 A1 CA2069318 A1 CA 2069318A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- composition
- alkyl
- phenyl
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42809789A | 1989-10-23 | 1989-10-23 | |
| US07/428,097 | 1989-10-27 | ||
| PCT/US1990/006102 WO1991006297A1 (fr) | 1989-10-27 | 1990-10-29 | (n-phthalimidoalkyle)piperidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2069318A1 true CA2069318A1 (fr) | 1991-04-28 |
Family
ID=23697544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002069318A Abandoned CA2069318A1 (fr) | 1989-10-27 | 1990-10-29 | (n-phthalimidoalkyl)piperidines |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0497843A4 (fr) |
| KR (1) | KR927002347A (fr) |
| CA (1) | CA2069318A1 (fr) |
| WO (1) | WO1991006297A1 (fr) |
| ZA (1) | ZA908641B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5356906A (en) * | 1989-10-27 | 1994-10-18 | The Du Pont Merck Pharmaceutical Company | (N-phthalimidoalkyl) piperidines useful as treatments for psychosis |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| US5180729A (en) * | 1991-02-22 | 1993-01-19 | Du Pont Merck Pharmaceutical Company | Use of sigma receptor antagonists for treatment of cocaine abuse |
| US5162341A (en) * | 1991-02-22 | 1992-11-10 | Du Pont Merck Pharmaceutical Company | Use of sigma receptor antagonists for treatment of amphetamine abuse |
| CA2134077C (fr) * | 1992-04-23 | 2002-05-21 | Thaddeus R. Nieduzak | 4-imidomethyl-1-[2'phenyl-2'oxoethyl-]piperidines servant de 5ht2-antagonistes de la serotonine, leur mode d'obtention et leur usage therapeutique |
| US5849760A (en) * | 1993-12-09 | 1998-12-15 | Institut De Recherche Jouveinal | 2-(arylalkenyl)azacycloalkane derivatives as ligands for sigma receptors |
| GB9416571D0 (en) * | 1994-08-16 | 1994-10-12 | Battelle Memorial Institute | Novel alkylamino derivatives as sigma 2 selective ligands |
| ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610736B (en) | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| HUP0004900A3 (en) * | 1997-10-24 | 2002-03-28 | Warner Lambert Co | Pharmaceutical compositions for treating disease-related or drug-induced dyskinesias containing piperidine derivatives as nmda receptor antagonist as active ingredient |
| CA2401711C (fr) * | 2000-02-29 | 2008-06-03 | Mitsubishi Pharma Corporation | Derives amide cycliques |
| EP1854798A3 (fr) * | 2000-09-19 | 2007-11-28 | Bristol-Myers Squibb Company | Composés de succinimide hétérocyclique fondu et leurs analogies, modulateurs de la fonction de récepteur d'hormone nucléaire |
| WO2002046156A2 (fr) * | 2000-12-06 | 2002-06-13 | Sepracor, Inc. | Piperidines 4,4-disubstituees leurs procedes d'utilisation |
| TWI263640B (en) * | 2001-12-19 | 2006-10-11 | Bristol Myers Squibb Co | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
| EP2377530A3 (fr) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation de neurogénèse par inhibition PDE |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2382975A3 (fr) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogénèse par modulation d'angiotensine |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2010099217A1 (fr) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine |
| EP3335731A1 (fr) * | 2010-07-20 | 2018-06-20 | Minerva Neurosciences, Inc. | Utilisation de dérivés d'amide cyclique pour traiter des troubles du sommeil |
| PT2595485T (pt) * | 2010-07-20 | 2022-05-30 | Minerva Neurosciences Inc | Métodos de utilização de derivados amida cíclica para tratar distúrbios mediados pelo recetor sigma |
| CA2968977A1 (fr) | 2014-12-02 | 2016-06-09 | Minerva Neurosciences, Inc. | Compositions contenant de la 2-((1-(2(4-fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one pour traiter la schizophrenie |
| AU2018290287B2 (en) | 2017-06-21 | 2024-06-13 | Minerva Neurosciences, Inc. | Gastro-resistant controlled release oral dosage forms |
| AU2019326525A1 (en) | 2018-08-21 | 2021-03-04 | Minerva Neurosciences, Inc. | Use of roluperidone to treat negative symptoms and disorders, increase neuroplasticity, and promote neuroprotection |
| US11919860B1 (en) | 2023-10-06 | 2024-03-05 | King Faisal University | 1-2(-(substituted phenyl)-2-oxoethyl)-4-(isopropoxycarbonyl)pyridin-1-ium bromides as anti-tubercular agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1425578A (en) * | 1972-10-21 | 1976-02-18 | Wyeth John & Brother Ltd | Piperidine derivatives |
| SE7907121L (sv) * | 1979-08-27 | 1981-02-28 | Astra Laekemedel Ab | Ftalimidinderivat |
| US4495194A (en) * | 1982-11-12 | 1985-01-22 | Mead Johnson & Company | Antihypertensive isoindole derivatives |
| NZ216720A (en) * | 1985-07-08 | 1990-09-26 | Bristol Myers Co | Diazinylpiperidine derivatives and pharmaceutical compositions |
| DE3717561A1 (de) * | 1987-05-25 | 1988-12-08 | Thomae Gmbh Dr K | Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
| AU593194B2 (en) * | 1986-09-26 | 1990-02-01 | Sumitomo Pharmaceuticals Company, Limited | Imide derivatives ,and their production and use |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
-
1990
- 1990-10-29 KR KR1019920700969A patent/KR927002347A/ko not_active Application Discontinuation
- 1990-10-29 CA CA002069318A patent/CA2069318A1/fr not_active Abandoned
- 1990-10-29 EP EP19900916143 patent/EP0497843A4/en not_active Withdrawn
- 1990-10-29 WO PCT/US1990/006102 patent/WO1991006297A1/fr not_active Application Discontinuation
- 1990-10-29 ZA ZA908641A patent/ZA908641B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991006297A1 (fr) | 1991-05-16 |
| EP0497843A1 (fr) | 1992-08-12 |
| KR927002347A (ko) | 1992-09-03 |
| EP0497843A4 (en) | 1992-09-23 |
| ZA908641B (en) | 1992-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |