CA2069106A1 - Proteines chimeriques - Google Patents

Proteines chimeriques

Info

Publication number
CA2069106A1
CA2069106A1 CA002069106A CA2069106A CA2069106A1 CA 2069106 A1 CA2069106 A1 CA 2069106A1 CA 002069106 A CA002069106 A CA 002069106A CA 2069106 A CA2069106 A CA 2069106A CA 2069106 A1 CA2069106 A1 CA 2069106A1
Authority
CA
Canada
Prior art keywords
peptide
protein
subunit
epitope region
ctb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002069106A
Other languages
English (en)
Inventor
Mark T. Dertzbaugh
Francis L. Macrina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Center for Innovative Technology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2069106A1 publication Critical patent/CA2069106A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA002069106A 1989-11-29 1990-11-28 Proteines chimeriques Abandoned CA2069106A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44278389A 1989-11-29 1989-11-29
US442,783 1989-11-29

Publications (1)

Publication Number Publication Date
CA2069106A1 true CA2069106A1 (fr) 1991-05-30

Family

ID=23758123

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002069106A Abandoned CA2069106A1 (fr) 1989-11-29 1990-11-28 Proteines chimeriques

Country Status (5)

Country Link
EP (1) EP0502099A4 (fr)
JP (1) JPH05503420A (fr)
CA (1) CA2069106A1 (fr)
IL (1) IL96475A0 (fr)
WO (1) WO1991007979A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043057A (en) * 1988-09-16 2000-03-28 Vitec Aktiebolag Recombinant systems for expression of the cholera B-sub-unit with the aid of foreign promoters and/or leader peptides
EP1266662A3 (fr) * 1992-05-01 2003-05-28 Forsyth Dental Infirmary For Children Vaccins de peptides de synthése pour prevenir les caries dentaires
US5681571A (en) * 1993-10-08 1997-10-28 Duotol Ab Immunological tolerance-inducing agent
GB9409387D0 (en) * 1994-05-11 1994-06-29 Unilever Plc Glucan-binding domains (gbp's) and hybird proteins containing gbd's as novel active systems targeted to dental plaque
MX9703676A (es) * 1994-11-17 1998-03-31 Maxim Pharm Inc Inmunogenos para estimular la inmunidad de las mucosas.
US5876727A (en) * 1995-03-31 1999-03-02 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
US6287566B1 (en) * 1995-05-19 2001-09-11 The United States Of America As Represented By The Secretary Of The Army Protective peptides neurotoxin of C. botulinum
EP0840796A2 (fr) * 1995-07-26 1998-05-13 Maxim Pharmaceuticals Apport de polynucleotides dans les muqueuses
US6036953A (en) * 1996-11-29 2000-03-14 The General Hospital Corporation Heterologous antigens in live cell V. cholerae strains
AU3291099A (en) * 1998-02-11 1999-08-30 Maxygen, Inc. Genetic vaccine vector engineering
ATE364395T1 (de) 1998-04-10 2007-07-15 Andrew Lees Konjugat-impfstoffe zur vorbeugung der zahnkaries
DE102011111688A1 (de) * 2011-08-24 2013-02-28 Bioserv Analytik Und Medizinprodukte Gmbh Verfahren zur schnellen Isolation bzw. Aufreinigung von rekombinanten Proteinen mit einer (nicht toxischen) Choleratoxin-Domäne

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56169215A (en) * 1980-05-28 1981-12-25 Tdk Corp Magnetic erasing head and its manufacture
FR2604021B1 (fr) * 1986-09-17 1988-10-28 Commissariat Energie Atomique Procede de realisation de tetes magnetiques en couches minces et a structure planaire et tete obtenue par ce procede
FR2636842B1 (fr) * 1988-09-27 1994-06-10 Liege Universite Etat Proteine de fusion d'une sequence derivee de la sous-unite b de la toxine cholerique et d'un antigene heterologue doue de proprietes immunogenes, compositions de vaccins les contenant et acides nucleiques recombinants contenant une sequence de nucleotides codant pour ladite proteine de fusion

Also Published As

Publication number Publication date
EP0502099A4 (en) 1993-02-17
WO1991007979A1 (fr) 1991-06-13
IL96475A0 (en) 1991-08-16
EP0502099A1 (fr) 1992-09-09
JPH05503420A (ja) 1993-06-10

Similar Documents

Publication Publication Date Title
EA007409B1 (ru) Антигенные полипептиды стрептококков, способы их получения и применения
JPH09501933A (ja) 植物、動物、およびヒトのワクチンとして並びに免疫療法に有用な抗体の免疫優性エピトープの弱化
CA2069106A1 (fr) Proteines chimeriques
CA2288234C (fr) Produits de synthese peptidiques permettant le diagnostic et le traitement de la desmodontite associee a la porphyromonas gingivalis
JP3023089B2 (ja) インフルエンザ菌用ワクチンおよび診断法
KR100527070B1 (ko) 치주염의진단및치료용포르피로모나스긴기발리스항원
JP2003520765A (ja) ポルフィロモナス・ジンジヴァリスによる歯周炎の治療及び予防のための保護エピトープを含有する合成ペプチド
CA2407603C (fr) Troncatures et proteines recombinees de porphyromonas gingivalis
KR0170752B1 (ko) 혈호균속 인플루엔자용 백신과 진단검사법
AU704882B2 (en) Vaccine for nontypable haemophilus influenzae strain
Jinshu et al. The immunogenicity of recombinant and dimeric gonadotrophin-releasing hormone vaccines incorporating a T-helper epitope and GnRH or repeated GnRH units
US5536497A (en) Fimbrial polypeptides useful in the prevention of periodontitis
JPH06511154A (ja) 組換えＢｏｒｒｅｌｉａタンパクの製造法
JP3135060B2 (ja) ヘモフィルスインフルエンザｂ型菌の外皮膜タンパク質Ｐ２の部分断片を用いた接合体
EP1090994A2 (fr) Immunogènes à séquences peptidiques répétitives
PT1616007E (pt) Proteínas inibidoras de uma protease e uso das mesmas
CA2202322A1 (fr) Epitopes de metalloprotease conserves
AU2001252042B2 (en) Porphyromonas gingivalis recombinant proteins and truncations
FR2699538A1 (fr) Sous-unité d'une capsule protéique CS31A modifiée par au moins un peptide hétérologue, capsule protéique CS31A et microorganismes portant ces sous-unités; procédés d'obtention et utilisation de ceux-ci.
CN115724940A (zh) 靶向STAT3蛋白Tyr705磷酸化的肽及其应用
JPH0347088A (ja) マラリア寄生虫分裂小体小器官抗原およびそれらの誘導体類
JPH03503359A (ja) 外来シグナルペプチド及び任意のトランスメンブレンアンカー配列を包含する遺伝子発現系（特にロタウイルスｖｐ７タンパク質）

Legal Events

Date Code Title Description
FZDE Discontinued